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Application of a Conceptual Nanomedical Platform to Facilitate the Mapping of the Human Brain: Survey of Cognitive Functions and Implications

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The Physics of the Mind and Brain Disorders

Part of the book series: Springer Series in Cognitive and Neural Systems ((SSCNS,volume 11))

Abstract

This chapter will explore the application of a conceptual nanomedical entity called the Vascular Cartographic Scanning Nanodevice (VCSN) to facilitate the ultrahigh resolution mapping of the human brain. The VCSN would comprise a highly sophisticated and completely autonomous ∼1 μm in diameter nanomedical device, whose purpose would be to safely ingress, scan and image the entire human vasculature (down to the level of the smallest ∼Ø3 μm lumen capillaries), followed by egress. In operation, likely thousands to tens of thousands of VCSN units would work in parallel to transmit cumulatively scanned spatial data to “outbody” computers, which would render the entire vasculature of a patient in high resolution three dimensional format. This capability would enable physicians and surgeons to “fly-through” all imaged areas via a joystick and computer display, generate full body holographic renderings, or inspect the entire vasculature in intimate detail through virtual reality. The human brain contains close to 100 billion capillaries within the neocortex, which serve to deliver a dedicated blood supply to each of the ∼23.9 × 109 individual neurons that support approximately 164 trillion synapses. Hence, it is plausible that the spatial coordinates of every neuron within the neocortex might be inferred from VCSN scanning data, to create an ultrahigh density map of the brain. This map might have significant utility and implications for the diagnosis, and treatment of various cognitive disorders, and potentially, toward the development of future cognitive augmentations, including the capacity for enhanced learning.

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Authors and Affiliations

  1. Angelika Domschke Consulting, LLC, Duluth, GA, USA

    Angelika Domschke

  2. NanoApps Medical, Inc., Vancouver, Canada

    Frank Josef Boehm

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  1. Angelika Domschke
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  2. Frank Josef Boehm
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Correspondence to Frank Josef Boehm .

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Editors and Affiliations

  1. Miami Project to Cure Paralysis, Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA

    Ioan Opris

  2. Greenville Health System, University of South Carolina, School of Medicine Greenville, Greenville, SC, USA

    Manuel F. Casanova

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Domschke, A., Boehm, F.J. (2017). Application of a Conceptual Nanomedical Platform to Facilitate the Mapping of the Human Brain: Survey of Cognitive Functions and Implications. In: Opris, I., Casanova, M.F. (eds) The Physics of the Mind and Brain Disorders. Springer Series in Cognitive and Neural Systems, vol 11. Springer, Cham. https://doi.org/10.1007/978-3-319-29674-6_33

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