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Slow Oscillation in Prefrontal Cortex Underlying Local Computations and Large-Scale Interactions

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The Physics of the Mind and Brain Disorders

Part of the book series: Springer Series in Cognitive and Neural Systems ((SSCNS,volume 11))

Abstract

Slow oscillation (4–8 Hz) in the prefrontal cortex is widely observed across species during various cognitive processes such as working memory. In humans and primates, the slow oscillation observed in the frontal area is termed ‘midline-frontal theta’ (FM-theta) oscillation. In rodents, the slow oscillation in the prefrontal cortex is termed ‘4-Hz’ oscillation. Although the generation mechanisms of FM-theta and 4-Hz oscillations have not been revealed yet, it is hypothesized that FM-theta in humans and 4-Hz in rodents have similar physiological properties and functions. Here, the roles of FM–theta and 4-Hz oscillations on cognitive functions and neuronal computations within local circuits and across large-scale brain networks are described.

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Authors and Affiliations

  1. RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan

    Shigeyoshi Fujisawa

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  1. Shigeyoshi Fujisawa
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Correspondence to Shigeyoshi Fujisawa .

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Editors and Affiliations

  1. Miami Project to Cure Paralysis, Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA

    Ioan Opris

  2. Greenville Health System, University of South Carolina, School of Medicine Greenville, Greenville, SC, USA

    Manuel F. Casanova

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Fujisawa, S. (2017). Slow Oscillation in Prefrontal Cortex Underlying Local Computations and Large-Scale Interactions. In: Opris, I., Casanova, M.F. (eds) The Physics of the Mind and Brain Disorders. Springer Series in Cognitive and Neural Systems, vol 11. Springer, Cham. https://doi.org/10.1007/978-3-319-29674-6_11

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