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Nanosystem in Ocular Bioenvironment

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Abstract

Delivering drugs at effective therapeutic concentrations to the ocular tissue with minimal side effects is a challenging task. Various physiological and anatomical barriers impede effective ocular delivery. Numerous approaches have been adapted to increase the bioavailability and the duration of drug action, but the effectiveness of drugs still have their limitations. Recently, nanotechnology-based drug delivery approaches have emerged as promising strategies for the delivery of water-soluble/water-insoluble drugs due to improved targeting capability, solubility, efficacy, and safety in administration. Here in this chapter, we have presented an overview of different biological barriers of ocular drug delivery and have reported how different nanocarriers are effective in ocular therapy with improved patient compliance.

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Authors and Affiliations

  1. Laboratory for Nanomedicine, Institute of Life Sciences, Nalco Square, Chandrasekharpur, Bhubaneswar, Orissa, India

    Fahima Dilnawaz & Sanjeeb Kumar Sahoo

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  1. Fahima Dilnawaz
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  2. Sanjeeb Kumar Sahoo
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Correspondence to Sanjeeb Kumar Sahoo .

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Editors and Affiliations

  1. College of Pharmacy, University of South Florida Health, Tampa, Florida, USA

    Yashwant Pathak

  2. College of Pharmacy, University of South Florida Health, Tampa, Florida, USA

    Vijaykumar Sutariya

  3. College of Pharmacy, University of South Florida, Tampa, Florida, USA

    Anjali A. Hirani

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Dilnawaz, F., Sahoo, S.K. (2016). Nanosystem in Ocular Bioenvironment. In: Pathak, Y., Sutariya, V., Hirani, A. (eds) Nano-Biomaterials For Ophthalmic Drug Delivery. Springer, Cham. https://doi.org/10.1007/978-3-319-29346-2_23

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