Abstract
Cardiovascular disease (CVD) is the leading cause of death in the United States. Across different manifestations of CVD, depression and anxiety disorders are common, under-recognized, and persistent. Furthermore, there is increasingly clear evidence that these psychiatric conditions are independent predictors of adverse cardiac events and mortality. Practitioners of behavioral medicine can play a vital role in managing patients with CVD by identifying common coping challenges and assessing patients at risk for mood and anxiety disorders. Though selective serotonin reuptake inhibitors (SSRIs) are safe and effective for treating anxiety disorders and depression among cardiac patients, there are several effective, well-tolerated, and evidence-based psychotherapeutic approaches. Cognitive behavioral therapy (CBT) and problem-solving therapy (PST) are the best-studied interventions and may be useful as stand-alone interventions or in the context of a collaborative medical-mental health care team approach. Several emerging therapies may also be useful, including mindfulness-based treatments and acceptance and commitment therapy (ACT). In addition, technological intervention delivery and telehealth programs can play important roles in reaching medically ill populations. Patients with comorbid CVD and anxiety or depression can experience relief from psychological symptoms with skillful application of evidence-based therapies and a team approach to care management.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Abbreviations
- ACS:
-
Acute coronary syndrome
- ACT:
-
Acceptance and commitment therapy
- CABG:
-
Coronary artery bypass graft
- CAD:
-
Coronary artery disease
- CBT:
-
Cognitive behavioral therapy
- CVD:
-
Cardiovascular disease
- GAD:
-
Generalized anxiety disorder
- HF:
-
Heart failure
- MBSR:
-
Mindfulness-based stress reduction
- MDD:
-
Major depressive disorder
- MI:
-
Myocardial infarction
- PD:
-
Panic disorder
- PP:
-
Positive psychology
- PST:
-
Problem-solving therapy
- PTSD:
-
Post-traumatic stress disorder
- QoL:
-
Quality of life
- SSRI:
-
Selective serotonin reuptake inhibitor
References
Roger V, Go A, Lloyd-Jones D, Adams R, Berry J, Brown T, et al. Heart disease and stroke statistics—2011 update: a report from the American Heart Association. Circulation. 2011;123(4):e18–209.
Thrall G, Lane D, Carroll D, Lip GY. Quality of life in patients with atrial fibrillation: a systematic review. Am J Med. 2006;119(5):448.e1–19.
Davidson KW, Kupfer DJ, Bigger JT, Califf RM, Carney RM, Coyne JC, et al. Assessment and treatment of depression in patients with cardiovascular disease: National Heart, Lung, and Blood Institute Working Group Report. Psychosom Med. 2006;68(5):645–50.
Celano CM, Huffman JC. Depression and cardiac disease: a review. Cardiol Rev. 2011;19(3):130–42.
Meijer A, Conradi HJ, Bos EH, Thombs BD, van Melle JP, de Jonge P. Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis of 25 years of research. Gen Hosp Psychiatry. 2011;33(3):203–16.
Huffman JC, Celano CM, Beach SR, Motiwala SR, Januzzi JL. Depression and cardiac disease: epidemiology, mechanisms, and diagnosis. Cardiovasc Psychiatry Neurol. 2013;2013:695925.
Ziegelstein RC, Kim SY, Kao D, Fauerbach JA, Thombs BD, McCann U, et al. Can doctors and nurses recognize depression in patients hospitalized with an acute myocardial infarction in the absence of formal screening? Psychosom Med. 2005;67(3):393–7.
Huffman JC, Celano CM, Januzzi JL. The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes. Neuropsychiatr Dis Treat. 2010;6:123–36.
Bankier B, Januzzi JL, Littman AB. The high prevalence of multiple psychiatric disorders in stable outpatients with coronary heart disease. Psychosom Med. 2004;66(5):645–50.
Huffman JC, Pollack MH, Stern TA. Panic disorder and chest pain: mechanisms, morbidity, and management. Prim Care Companion J Clin Psychiatry. 2002;4(2):54–62.
Roest AM, Zuidersma M, de Jonge P. Myocardial infarction and generalised anxiety disorder: 10-year follow-up. Br J Psychiatry. 2012;200(4):324–9.
Tulloch H, Greenman PS, Tasse V. Post-traumatic stress disorder among cardiac patients: prevalence, risk factors, and considerations for assessment and treatment. Behav Sci. 2014;5(1):27–40.
Watkins LL, Koch GG, Sherwood A, Blumenthal JA, Davidson JR, O’Connor C, et al. Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease. J Am Heart Assoc. 2013;2(2):e000068.
Lett HS, Blumenthal JA, Babyak MA, Sherwood A, Strauman T, Robins C, et al. Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment. Psychosom Med. 2004;66(3):305–15.
Bondy B, Baghai TC, Zill P, Bottlender R, Jaeger M, Minov C, et al. Combined action of the ACE D- and the G-protein beta3 T-allele in major depression: a possible link to cardiovascular disease? Mol Psychiatry. 2002;7(10):1120–6.
Rozanski A, Blumenthal JA, Davidson KW, Saab PG, Kubzansky L. The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology. J Am Coll Cardiol. 2005;45(5):637–51.
Linden W, Phillips MJ, Leclerc J. Psychological treatment of cardiac patients: a meta-analysis. Eur Heart J. 2007;28(24):2972–84.
Freedland KE, Skala JA, Carney RM, Rubin EH, Lustman PJ, Davila-Roman VG, et al. Treatment of depression after coronary artery bypass surgery: a randomized controlled trial. Arch Gen Psychiatry. 2009;66(4):387–96.
Berkman LF, Blumenthal J, Burg M, Carney RM, Catellier D, Cowan MJ, et al. Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. JAMA. 2003;289(23):3106–16.
Davidson KW, Rieckmann N, Clemow L, Schwartz JE, Shimbo D, Medina V, et al. Enhanced depression care for patients with acute coronary syndrome and persistent depressive symptoms: coronary psychosocial evaluation studies randomized controlled trial. Arch Intern Med. 2010;170(7):600–8.
Davidson KW, Bigger JT, Burg MM, Carney RM, Chaplin WF, Czajkowski S, et al. Centralized, stepped, patient preference-based treatment for patients with post-acute coronary syndrome depression: CODIACS vanguard randomized controlled trial. JAMA Intern Med. 2013;173(11):997–1004.
Glassman AH, O’Connor CM, Califf RM, Swedberg K, Schwartz P, Bigger Jr JT, et al. Sertraline treatment of major depression in patients with acute MI or unstable angina. JAMA. 2002;288(6):701–9.
Huffman JC, Mastromauro CA, Beach SR, Celano CM, Dubois CM, Healy BC, et al. Collaborative care for depression and anxiety disorders in patients with recent cardiac events: the Management of Sadness and Anxiety in Cardiology (MOSAIC) randomized clinical trial. JAMA Intern Med. 2014;174(6):927–35.
Irvine J, Firestone J, Ong L, Cribbie R, Dorian P, Harris L, et al. A randomized controlled trial of cognitive behavior therapy tailored to psychological adaptation to an implantable cardioverter defibrillator. Psychosom Med. 2011;73(3):226–33.
Berman MI, Buckey Jr JC, Hull JG, Linardatos E, Song SL, McLellan RK, et al. Feasibility study of an interactive multimedia electronic problem solving treatment program for depression: a preliminary uncontrolled trial. Behav Ther. 2014;45(3):358–75.
Choi NG, Hegel MT, Marinucci ML, Sirrianni L, Bruce ML. Association between participant-identified problems and depression severity in problem-solving therapy for low-income homebound older adults. Int J Geriatr Psychiatry. 2012;27(5):491–9.
Ziegelstein RC, Fauerbach JA, Stevens SS, Romanelli J, Richter DP, Bush DE. Patients with depression are less likely to follow recommendations to reduce cardiac risk during recovery from a myocardial infarction. Arch Intern Med. 2000;160(12):1818–23.
Bauer LK, Caro MA, Beach SR, Mastromauro CA, Lenihan E, Januzzi JL, et al. Effects of depression and anxiety improvement on adherence to medication and health behaviors in recently hospitalized cardiac patients. Am J Cardiol. 2012;109(9):1266–71.
Hibbard JH, Mahoney ER, Stock R, Tusler M. Do increases in patient activation result in improved self-management behaviors? Health Serv Res. 2007;42(4):1443–63.
Sears SF, Woodrow L, Cutitta K, Ford J, Shea JB, Cahill J. A patient’s guide to living confidently with chronic heart failure. Circulation. 2013;127(13):e525–8.
Burns DD. The feeling good handbook. New York: Plume; 1999.
Burg MM, Abrams D. Depression in chronic medical illness: the case of coronary heart disease. J Clin Psychol. 2001;57(11):1323–37.
Unützer J, Katon W, Callahan CM, Williams Jr JW, Hunkeler E, Harpole L, et al. Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial. JAMA. 2002;288(22):2836–45.
Arean P, Hegel M, Vannoy S, Fan M-Y, Unuzter J. Effectiveness of problem-solving therapy for older, primary care patients with depression: results from the IMPACT project. Gerontologist. 2008;48(3):311–23.
Gallegos AM, Hoerger M, Talbot NL, Krasner MS, Knight JM, Moynihan JA, et al. Toward identifying the effects of the specific components of mindfulness-based stress reduction on biologic and emotional outcomes among older adults. J Altern Complement Med. 2013;19(10):787–92.
Kabat-Zinn J. Mindfulness-based interventions in context: past, present, and future. Clin Psychol Sci Pract. 2003;10(2):144–56.
Addis M, Davis M. Meditation may reduce heart attack and stroke risk. Lancet. 2000;355.
Chang BH, Dusek JA, Benson H. Psychobiological changes from relaxation response elicitation: long-term practitioners vs. novices. Psychosomatics. 2011;52(6):550–9.
Chang BH, Hendricks A, Zhao Y, Rothendler JA, LoCastro JS, Slawsky MT. A relaxation response randomized trial on patients with chronic heart failure. J Cardiopulm Rehabil. 2005;25(3):149–57.
Herbert Benson M, Klipper MZ. The relaxation response. New York: Harper Collins; 1992.
Swartz HA, Frank E, Shear MK, Thase ME, Fleming MA, Scott J. A pilot study of brief interpersonal psychotherapy for depression among women. Psychiatr Serv. 2004;55(4):448–50.
Lespérance F, Frasure-Smith N, Koszycki D, Laliberté M-A, van Zyl LT, Baker B, et al. Effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease: the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial. JAMA. 2007;297(4):367–79.
Lett HS, Davidson J, Blumenthal JA. Nonpharmacologic treatments for depression in patients with coronary heart disease. Psychosom Med. 2005;67 Suppl 1:S58–62.
Goodwin CL, Forman EM, Herbert JD, Butryn ML, Ledley GS. A pilot study examining the initial effectiveness of a brief acceptance-based behavior therapy for modifying diet and physical activity among cardiac patients. Behav Modif. 2012;36(2):199–217.
Sin NL, Lyubomirsky S. Enhancing well-being and alleviating depressive symptoms with positive psychology interventions: a practice-friendly meta-analysis. J Clin Psychol. 2009;65(5):467–87.
Chida Y, Steptoe A. Positive psychological well-being and mortality: a quantitative review of prospective observational studies. Psychosom Med. 2008;70(7):741–56.
Scheier MF, Matthews KA, Owens JF, Schulz R, Bridges MW, Magovern GJ, et al. Optimism and rehospitalization after coronary artery bypass graft surgery. Arch Intern Med. 1999;159(8):829–35.
Huffman JC, Mastromauro CA, Boehm JK, Seabrook R, Fricchione GL, Denninger JW, et al. Development of a positive psychology intervention for patients with acute cardiovascular disease. Heart Int. 2011;6(2):e14.
Seligman ME, Steen TA, Park N, Peterson C. Positive psychology progress: empirical validation of interventions. Am Psychol. 2005;60(5):410–21.
Lyubomirsky S, Layous K. How do simple positive activities increase well-being? Curr Direct Psychol Sci. 2013;22(1):57–62.
Rollman BL, Belnap BH, LeMenager MS, Mazumdar S, Houck PR, Counihan PJ, et al. Telephone-delivered collaborative care for treating post-CABG depression: a randomized controlled trial. JAMA. 2009;302(19):2095–103.
Katon WJ, Lin EH, Von Korff M, Ciechanowski P, Ludman EJ, Young B, et al. Collaborative care for patients with depression and chronic illnesses. N Engl J Med. 2010;363(27):2611–20.
Spurgeon JA, Wright JH. Computer-assisted cognitive-behavioral therapy. Curr Psychiatry Rep. 2010;12(6):547–52.
Luxton DD, McCann RA, Bush NE, Mishkind MC, Reger GM. mHealth for mental health: integrating smartphone technology in behavioral healthcare. Prof Psychol Res Pract. 2011;42(6):505.
Donker T, Petrie K, Proudfoot J, Clarke J, Birch MR, Christensen H. Smartphones for smarter delivery of mental health programs: a systematic review. J Med Internet Res. 2013;15(11):e247.
Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–13.
Beck A, Steer R, Brown G. Manual for beck depression inventory-II (BDI-II). San Antonio: Psychology Corporation; 1996.
Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–70.
Ware Jr J, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34(3):220–33.
Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24(4):385–96.
Hlatky MA, Boineau RE, Higginbotham MB, Lee KL, Mark DB, Califf RM, et al. A brief self-administered questionnaire to determine functional capacity (the Duke Activity Status Index). Am J Cardiol. 1989;64(10):651–4.
Green CP, Porter CB, Bresnahan DR, Spertus JA. Development and evaluation of the Kansas City Cardiomyopathy Questionnaire: a new health status measure for heart failure. J Am Coll Cardiol. 2000;35(5):1245–55.
Spertus JA, Winder JA, Dewhurst TA, Deyo RA, Prodzinski J, McDonell M, et al. Development and evaluation of the Seattle Angina Questionnaire: a new functional status measure for coronary artery disease. J Am Coll Cardiol. 1995;25(2):333–41.
DiMatteo MR, Hays RD, Sherbourne CD. Adherence to cancer regimens: implications for treating the older patient. Oncology (Williston Park). 1992;6(2 Suppl):50–7.
Eifert GH, Thompson RN, Zvolensky MJ, Edwards K, Frazer NL, Haddad JW, et al. The cardiac anxiety questionnaire: development and preliminary validity. Behav Res Ther. 2000;38(10):1039–53.
Hare DL, Davis CR. Cardiac Depression Scale: validation of a new depression scale for cardiac patients. J Psychosom Res. 1996;40(4):379–86.
Resources
American Heart Association. Coping with feelings. http://www.heart.org/HEARTORG/Conditions/More/CardiacRehab/Coping-with-Feelings_UCM_307092_Article.jsp
American Heart Association. Stress and heart health. http://www.heart.org/HEARTORG/GettingHealthy/StressManagement/HowDoesStressAffectYou/Stress-and-Heart-Health_UCM_437370_Article.jsp
Anxiety and Depression Association of America. Managing stress for heart health. http://www.adaa.org/about-adaa/press-room/press-releases/managing-stress-for-heart-health
Oxford University Press. Treatments that work series. http://global.oup.com/us/companion.websites/umbrella/treatments/
Greenberger D, Padesky CA. Mind over mood. New York: Guilford; 1995.
University of Washington. Problem solving therapy materials. http://impact-uw.org/tools/pst_manual.html
Mindfulness-based stress reduction materials. http://www.mindfullivingprograms.com/index.php
The relaxation response materials. http://www.relaxationresponse.org
Benson H. The relaxation response. New York: Harper Torch; 1975/2000.
Web-based CBT. https://www.beatingthebluesus.com/
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer Science+Business Media New York
About this chapter
Cite this chapter
Millstein, R.A., Huffman, J.C. (2017). Psychosocial Management of Patients with Heart Disease. In: Vranceanu, AM., Greer, J., Safren, S. (eds) The Massachusetts General Hospital Handbook of Behavioral Medicine. Current Clinical Psychiatry. Humana Press, Cham. https://doi.org/10.1007/978-3-319-29294-6_10
Download citation
DOI: https://doi.org/10.1007/978-3-319-29294-6_10
Published:
Publisher Name: Humana Press, Cham
Print ISBN: 978-3-319-29292-2
Online ISBN: 978-3-319-29294-6
eBook Packages: MedicineMedicine (R0)