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Hypertension and Stroke pp 233–244Cite as

Blood Pressure Variability, Antihypertensive Therapy and Stroke Risk

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Part of the book series: Clinical Hypertension and Vascular Diseases ((CHVD))

Abstract

Raised blood pressure is an important predictor of stroke risk. Over time it has become apparent that stroke risk prediction may be enhanced by blood pressure measures other than usual office (mean) cuff blood pressure determinations. Blood pressure variability and circadian variations of blood pressure such as morning surge of blood pressure and nocturnal dipping status (e.g., non-dipping, exaggerated dipping) have proven to be useful indicators of stroke risk. Such features of blood pressure status may be captured by ambulatory blood pressure monitoring which is now considered a valuable technology for determination of blood pressure status. In this chapter we review circadian patterns and types of blood pressure variability and discuss blood pressure variability as a risk for stroke, the means to measure it, its long-term consequences, and how blood pressure variability is being incorporated into stroke prevention guidelines for diagnosis and treatment of hypertension.

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Authors and Affiliations

  1. Division of Stroke and Vascular Neurology, Mercy Health Hauenstein Neurosciences, 200 Jefferson Street SE, Grand Rapids, MI, 49503, USA

    Muhammad U. Farooq M.D., F.A.C.P., F.A.H.A. & Jiangyong Min M.D., Ph.D.

  2. Department of Medicine and Therapeutics, Faculty of Medicine, Prince of Wales Hospital, Chinese University of Hong Kong, 9/F., Lui Che Woo Clinical Science Building, Hong Kong, China

    Lawrence K. S. Wong M.D.

  3. Department of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, 220 Cherry Street SE Room H 3037, Grand Rapids, MI, 49503, USA

    Philip B. Gorelick M.D., M.P.H., F.A.C.P. (Professor, Medical Director)

  4. Mercy Health Hauenstein Neurosciences, 220 Cherry Street SE Room H 3037, Grand Rapids, MI, 49503, USA

    Philip B. Gorelick M.D., M.P.H., F.A.C.P. (Professor, Medical Director)

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  1. Muhammad U. Farooq M.D., F.A.C.P., F.A.H.A.
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  2. Jiangyong Min M.D., Ph.D.
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  3. Lawrence K. S. Wong M.D.
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  4. Philip B. Gorelick M.D., M.P.H., F.A.C.P.
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Correspondence to Muhammad U. Farooq M.D., F.A.C.P., F.A.H.A. .

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Editors and Affiliations

  1. Departments of Neurological Surgery and Neurology and Neurotherapeutics , University of Texas Southwestern Medical Center , Dallas, Texas, USA

    Venkatesh Aiyagari

  2. Michigan State University Department of Translational Science & Molecular Medicine, Mercy Health Hauenstein Neurosciences, Grand Rapids, Michigan, USA

    Philip B. Gorelick

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Farooq, M.U., Min, J., Wong, L.K.S., Gorelick, P.B. (2016). Blood Pressure Variability, Antihypertensive Therapy and Stroke Risk. In: Aiyagari, V., Gorelick, P. (eds) Hypertension and Stroke. Clinical Hypertension and Vascular Diseases. Humana Press, Cham. https://doi.org/10.1007/978-3-319-29152-9_13

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