Abstract
A significant correlation exists between malnutrition and the development of complications after orthopedic injuries. Impaired wound and bone healing, increased rate of wound infection, sepsis, progressive weakness, lethargy, delayed union/malunion, and delayed physical rehabilitation are all documented. The prevalence of patients malnourished or at risk for malnutrition among those hospitalized for orthopedic procedures goes up to 50 % in poor income countries, compared to 23–33 % in western countries. The post-trauma catabolic state is accentuated by the frequent period of food deprivation that commonly follows trauma. An optimal definition of malnutrition, especially in adults, is still lacking making sometimes difficult to recognize the subtle features of undernourishment. Currently, a simple clinical assessment of the patient’s status (subjective global assessment (SGA)) performed by an experienced physician may be considered reliable to sensibly estimate the nutritional state. Increasing the understanding of the role of nutrition in orthopedic trauma is therefore the first important step toward a successful outcome. Given the scarcity of resources, in the absence of oral supplementation with highly nutrient food, enteral nutrition is the alternative route of administration. This should be based on locally available food ingredients and not on sophisticated formulas or solutions imported from abroad. Micronutrients and immune-enhancing components, whose role is well acknowledged in western countries, are not widely available or used in austere and trauma settings.
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References
Smith TK. Prevention of complications in orthopedic surgery secondary to nutritional depletion. Clin Orthop Relat Res. 1987;222:91–7.
Smith TK. Nutrition: its relationship to orthopedic infections. Orthop Clin North Am. 1991;223:373–7.
Jensen JE, Jensen TG, Smith TK, et al. Nutrition in orthopaedic surgery. J Bone Joint Surg Am. 1982;64:1263–7.
Gumieiro DN, Rafacho BP, Gonçalves AF, et al. Mini nutritional assessment predicts gait status and mortality 6 months after hip fracture. Br J Nutr. 2012;28:1–5.
Symeonidis PD, Clark D. Assessment of malnutrition in hip fracture patients: effects on surgical delay, hospital stay and mortality. Acta Orthop Belg. 2006;72:420–7.
O'Daly BJ, Walsh JC, Quinlan JF, et al. Serum albumin and total lymphocyte count as predictors of outcome in hip fractures. Clin Nutr. 2010;29:89–93.
Salignon P, Cabrol JC, Liu J, et al. Health and war in Congo-Brazzaville. Lancet. 2000;356:1762.
Shretha BK, Rajbhandary T, Bijukachhe B, et al. Surgical interventions in chronic osteomyelitis. Kathmandu Univ Med J. 2005;3:50–4.
Baxter JP. Problems of the nutritional assessment in the acute setting. Proc Nutr Soc. 1999;58:39–46.
FAO. The state of food insecurity in the world. 2006. http://www.fao.org/docrep/009/a0750e/a0750e00.htm. Accessed 12 July 2013.
WHO. Management of severe malnutrition. A manual for physician s and other senior health workers. 1999. http://www.who.int/nutrition/publications/severemalnutrition/manage_severe_malnutrition_eng_cover.pdf. Accessed 4 June 2013.
Prentice AM, Moore SE, Fulford AJ. Growth faltering in low-income countries. World Rev Nutr Diet. 2013;106:90–9.
Corish CA, Kennedy NP. Protein energy undernutrition in hospital in-patients. Br J Nutr. 2000;83:575–91.
Middleton MH, Nazarenko G, Nivison-Smith I, et al. Prevalence of malnutrition and 12-month incidence of mortality in two Sydney teaching hospitals. Intern Med J. 2001;31:455–61.
Edington J, Boorman J, Durrant ER, et al. Prevalence of malnutrition on admission to four hospitals in England. The Malnutrition Prevalence Group. Clin Nutr. 2000;19:191–5.
Eneroth M, Apelqvist J, Larsson J, et al. Improved wound healing in transtibial amputees receiving supplementary nutrition. Int Orthop. 1997;21:104–8.
Dwyer AJ, John B, Mam MK, et al. Nutritional status and wound healing in open fractures of the lower limb. Int Orthop. 2005;29:251–4.
Dreblow DM, Anderson CF, Moxness K. Nutritional assessment of orthopedic patients. Mayo Clin Proc. 1981;56:51–4.
Foster MR, Heppenstall RB, Friedenberg ZB, et al. A prospective assessment of nutritional status and complications in patients with fractures of the hip. J Orthop Trauma. 1990;4:49–57.
Goiburu ME, Jure Goiburu MM, Bianco H, et al. The impact of malnutrition on morbidity, mortality and length of hospital stay in trauma patients. Nutr Hosp. 2006;21:604–10.
Patton CM, Powell AP, Patel AA. Vitamin D in orthopedics. J Am Acad Orthop Surg. 2012;20:123–9.
Bogunovic L, Kim AD, Beamer BS, et al. Hypovitaminosis D in patients scheduled to undergo orthopaedic surgery: a single-center analysis. J Bone Joint Surg Am. 2010;92:2300–4.
Nawabi DH, Chin KF, Keen RW, et al. Vitamin D deficiency in patients with osteoarthritis undergoing total hip replacement: a cause for concern? J Bone Joint Surg Br. 2010;92:496–9.
Parry J, Sullivan E, Scott AC. Vitamin D sufficiency screening in preoperative pediatric orthopaedic patients. J Pediatr Orthop. 2011;31:331–3.
Wahlqvist ML. Vitamin D status and food security in North-East Asia. Asia Pac J Clin Nutr. 2013;22:1–5.
Mithal A, Wahl DA, Bonjour JP, et al. Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int. 2009;2:1807–20.
Al-Mogbel ES. Vitamin D status among Adult Saudi Females visiting Primary Health Care Clinics. Int J Health Sci (Qassim). 2012;6:116–26.
Halicioglu O, Aksit S, Koc F, et al. Vitamin D deficiency in pregnant women and their neonates in spring time in western Turkey. Paediatr Perinat Epidemiol. 2012;26:53–60.
Szalay EA, Tryon EB, Pleacher MD, et al. Pediatric vitamin D deficiency in a southwestern luminous climate. J Pediatr Orthop. 2011;31:469–73.
Sadat-Ali M, AlElq A, Al-Turki H, et al. Vitamin D levels in healthy men in eastern Saudi Arabia. Ann Saudi Med. 2010;29:378–82.
Tanriover MD, Oz SG, Tanriover A, et al. Hip fractures in a developing country: osteoporosis frequency, predisposing factors and treatment costs. Arch Gerontol Geriatr. 2010;50:e13–8.
Avenell A, Gillespie WJ, Gillespie LD, et al. Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post- menopausal osteoporosis. Cochrane Database Syst Rev. 2009;(2):CD000227.
Sanders KM, Stuart AL, Williamson EJ, et al. Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial. JAMA. 2010;303:1815–22.
Birkhahn RH, Long CL, Fitkin D, et al. Effects of major skeletal trauma on whole body protein turnover in man measured by L-[1,14C]-leucine. Surgery. 1980;88:294–300.
Manious MR, Deitch EA. Nutrition and infection. Surg Clin North Am. 1994;74:659–76.
Hill N, Fallowfield J, Price S, et al. Military nutrition: maintaining health and rebuilding injured tissue. Philos Trans R Soc Lond B Biol Sci. 2011;366:231–40.
Plank LD, Hill GL. Sequential metabolic changes following induction of systemic inflammatory response in patients with severe sepsis or major blunt trauma. World J Surg. 2000;24:630–8.
Duff S, Price S, Gray J. The role of nutrition in injured military personnel at Role 4: current practice. J R Army Med Corps. 2008;154:284–91.
Schneider SM, Veyres P, Pivot X, et al. Malnutrition is an independent factor associated with nosocomial infections. Br J Nutr. 2004;92:105–11.
Windsor JA, Knight GS, Hill GL. Wound healing response in surgical patients: recent food intake is more important than nutritional status. Br J Surg. 1988;75:135–7.
Meijers JM, van Bokhorst-de van der Schueren MA, Schols JM, et al. Defining malnutrition: mission or mission impossible? Nutrition. 2010;26:432–40.
WHO. Turning the tide of malnutrition: responding to the challenge of 21st century. 2000. http://www.who.int/nut/documents/nhd_brochure.pdf. Accessed 14 July 2013.
Lazzerini M, Rubert L, Ronfani L, et al. Specially formulated foods for treating children with acute moderate malnutrition in low- and middle-income countries (Protocol). The Cochrane Library. 2012;(1):CD009584.
Caleo GM, Penda A, Balandine S, et al. Sentinel site community surveillance of mortality and nutritional status in southwestern Central African Republic, 2010. Popul Health Metr. 2012;10:18.
Detsky AS, Baker JP, Mendelson RA, et al. Evaluating the accuracy of nutritional assessment techniques applied to hospitalized patients: methodology and comparisons. JPEN J Parenter Enteral Nutr. 1984;8:153–9.
Vellas B, Villars H, Abellan G, et al. Overview of MNA® – its history and challenges. J Nut Health Aging. 2006;10:456–65.
Bauer JM, Kaiser MJ, Anthony P, et al. The Mini Nutritional Assessment: its history, today’s practice, and future perspectives. Nutr Clin Pract. 2008;23:388–96.
Elia M. The ‘MUST’ report. Nutritional screening for adults: a multidisciplinary responsibility. 2003. http://www.bapen.org.uk/pdfs/must/must_exec_sum.pdf. Accessed 14 July 2013.
Buzby GP, Knox LS, Crosby LO, et al. Study protocol: a randomized clinical trial of total parenteral nutrition in malnourished surgical patients. Am J Clin Nutr. 1988;47:366–81.
Kondrup J, Johansen N, Plum LM, et al. Incidence of nutritional risk and causes of inadequate nutritional care in hospitals. Clin Nutr. 2002;21:461–8.
Bouillanne O, Morineau G, Dupont C, et al. Geriatric Nutritional Risk Index: a new index for evaluating at-risk elderly medical patients. Am J Clin Nutr. 2005;82:777–83.
Falcao MC, Cardoso LEMB. Avaliação nutricional do recémnascido pré-termo. Rev Bras Nutr Clin. 2001;16:144–7.
McClave SA, Snider HL, Spain DA. Preoperative issues in clinical nutrition. Chest. 1999;115:64S–70.
Del Savio GC, Zelicof SB, Wexler LM, et al. Preoperative nutritional status and outcome of elective total hip replacement. Clin Orthop Relat Res. 1996;326:153–61.
Schwals WJ, Fernandez ME, Jamie AC, et al. Relationship of metabolic indices to postoperative mortality in surgical infants. J Pediatr Surg. 1993;28:819–22.
Fuhrman MP, Winkler M, Biesemeier C. The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Standards of Practice for nutrition support dietitians. J Am Diet Assoc. 2001;101:825–32.
Dickhaut SC, DeLee JC, Page CP. Nutritional status: importance in predicting wound-healing after amputation. J Bone Joint Surg Am. 1984;66:71–5.
Kay SP, Moreland JR, Schmitter E. Nutritional status and wound healing in lower extremity amputations. Clin Ortop. 1987;217:253–6.
Covinsky KE, Martin GE, Beyth RJ, et al. The relationship between clinical assessments of nutritional status and adverse outcomes in older hospitalized medical patients. J Am Geriatr Soc. 1999;47:532–8.
Windsor A, Braga M, Martindale R, et al. Fit for surgery: an expert panel review on optimising patients prior to surgery, with a particular focus on nutrition. Surgeon. 2004;2:315–9.
Jeejeebhoy KN, Detsky AS, Baker JP. Assessment of nutritional status. J Parenter Enteral Nutr. 1990;14:193S–6.
Woolf SH, Grol R, Hutchinson A, et al. Clinical guidelines: potential benefits, limitations, and harms of clinical guidelines. BMJ. 1999;318:527–30.
Arnold M, Barbul A. Nutrition and wound healing. Plast Reconstr Surg. 2006;117:42S–58.
Campos ACL, Groth AK, Branco A. Assessment and nutritional aspects of wound healing. Curr Opin Clin Nutr Metab Care. 2008;11:281–8.
Pratt WB, Veitch JM, McRoberts RL. Nutritional status of orthopedic patients with surgical complications. Clin Orthop Relat Res. 1981;155:81–4.
Greene KA, Wilde AH, Stulberg BN. Preoperative nutritional status of total joint patients. Relationship to postoperative wound complications. J Arthroplasty. 1991;6:321–5.
Koval KJ, Maurer SG, Su ET, et al. The effects of nutritional status on outcome after hip fracture. J Orthop Trauma. 1999;13:164–9.
Bonjour JP. Protein intake and bone health. Int J Vitam Nutr Res. 2011;81:134–42.
Bak B, Andreassen TT. Reduced energy absorption of healed fracture in the rat. Acta Orthop Scand. 1988;59:548–51.
Hughes MS, Kazmier P, Burd TA, et al. Enhanced fracture and soft-tissue healing by means of anabolic dietary supplementation. J Bone Joint Surg Am. 2006;88:2386–94.
Brinker MR. Nonunions: evaluation and treatment. In: Browner BD, Levine AM, Jupiter JB, et al., editors. Skeletal trauma: basic science, management, and reconstruction. Philadelphia: WB Saunders; 2003. p. 507–604.
Day SM, DeHeer DH. Reversal of the detrimental effects of chronic protein malnutrition on long bone fracture healing. J Orthop Trauma. 2001;15:47–53.
Schwarzkopf R, Russell TA, Shea M, et al. Correlation between nutritional status and staphylococcus colonization in hip and knee replacement patients. Bull NYU Hosp Jt Dis. 2011;9:308–11.
Avenell A, Handoll HH. Nutritional supplementation for hip fracture after care in older people. Cochrane Database Syst Rev. 2006;(4):CD001880.
Frizzi JD, Ray PD, Raff JB. Enteral nutrition by a Forward Surgical Team in Afghanistan. South Med J. 2005;98:273–8.
Awad S, Constantin-Teodosiu D, Macdonald IA, et al. Short-term starvation and mitochondrial dysfunction – a possible mechanism leading to post- operative insulin resistance. Clin Nutr. 2009;28:497–509.
Brady MC, Kinn S, Stuart P, et al. Preoperative fasting for adults to prevent perioperative complications (review). Cochrane Database Syst Rev. 2003. http://onlinelibrary.wiley.com/o/cochrane/clsysrev/articles/CD004423/frame.html. Accessed 11 July 2013.
Weimann A, Braga M, Harsanyic L, et al. ESPEN guidelines on enteral nutrition: surgery including organ transplantation. Clin Nutr. 2006;25:224–44.
American Society of Anesthesiologists. Guidelines for preoperative fasting and the use of pharmacologic agents to reduce the risk of pulmonary aspiration: application to healthy patients undergoing elective procedures an updated report by the American Society of Anesthesiologists Committee on Standards and Practice Parameters. Anesthesiology. 2011;114:495–511.
Kratzing C. Pre-operative nutrition and carbohydrate loading. Proc Nutr Soc. 2011;70:311–5.
Awad S, Varadhan KK, Ljungqvist O, et al. A meta-analysis of randomised controlled trials on preoperative oral carbohydrate treatment in elective surgery. Clin Nutr. 2013;32:34–44.
Soop M, Nygren J, Myrenfors P, et al. Preoperative oral carbohydrate treatment attenuates immediate postoperative insulin resistance. Am J Physiol Endocrinol Metab. 2001;280:E576–83.
Soop M, Nygren J, Thorell A, et al. Preoperative oral carbohydrate treatment attenuates endogenous glucose release 3 days after surgery. Clin Nutr. 2004;23:733–41.
Klein S, Kinney J, Jeejeebhoy K, et al. Nutrition support in clinical practice: review of published data and recommendations for future research directions. J Parenter Enteral Nutr. 1997;21:133–46.
Jacobs DG, Plaisier BR, Baries PS, et al. Practice management guidelines for nutritional support of the trauma patient. J Trauma. 2003;54:391–416.
Lawson RM, Doshi MK, Ingoe LE, et al. Compliance of orthopaedic patients with postoperative oral nutritional supplementation. Clin Nutr. 2000;19:171–5.
Sullivan DH, Nelson CL, Klimberg VS, et al. Nightly enteral nutrition support of elderly hip fracture patients: a pilot study. J Am Coll Nutr. 2004;23:683–91.
Kudsk KA. Gut mucosal nutritional support – enteral nutrition as primary therapy after multiple trauma. Gut. 1994;35:S52–541.
Deitch EA, Winterton J, Li M, et al. The gut as a portal of entry for bacteremia. Role of protein malnutrition. Ann Surg. 1987;205:681–92.
Henning J, Scott T, Price S. Nutrition of the critically ill patient in field hospitals on operations. J R Army Med Corps. 2008;154:279–81.
Critical Care Nutrition. Strategies to optimize delivery and minimize risks of EN: small bowel versus gastric feedings. 2009. http://www.criticalcarenutrition.com/docs/cpg/5.3Smallbowel_FINAL.pdf. Accessed 10 May 2013.
Cerra FB, Benitez MR, Blackburn GL, et al. Applied nutrition in ICU patients. A consensus statement of the American College of Chest Physicians. Chest. 1997;111:769–78.
Pardoe EM. Tube feeding syndrome revisited. Nutr Clin Pract. 2001;16:144–6.
Schloerb PR. Immune-enhancing diets: products, components, and their rationales. J Parenter Enteral Nutr. 2001;25:S3–7.
Stechmiller JK. Understanding the role of nutrition and wound healing. Nutr Clin Pract. 2010;25:61–8.
Cerantola Y, Hübner M, Grass F, et al. Immunonutrition in gastrointestinal surgery. Br J Surg. 2011;98:37–48.
Mechanik JA. Practical aspects of nutritional support for wound healing patients. Am J Surg. 2004;188:52S–6.
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Contini, S. (2016). Malnutrition and Orthopedic Injuries. In: Robinson, J. (eds) Orthopaedic Trauma in the Austere Environment. Springer, Cham. https://doi.org/10.1007/978-3-319-29122-2_11
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