Abstract
The definition of “aggressive” pituitary adenomas varies with the different specialties in charge of pituitary gland tumors. For the pathologist, for instance, “aggressivity” means that the dura of the sellar region is invaded, even if this is not recognized by the neurosurgeon, or if proliferation markers such as Ki-67 or P53 are detected. Radiologists may have their own definition.
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Further Reading
Chen X, Dai J, Ai L et al (2011) Clival invasion on multi-detector CT in 390 pituitary macroadenomas: correlation with sex, subtype and rates of operative complication. AJNR Am Neuroradiol 32(4):785–789
Potorac I, Petrossians P, Daly AF et al (2015) Pituitary MRI characteristics in 297 acromegaly patients based on T2-weighted sequences. Endocrinol Relat Cancer 22(2):169–177
Scheithauer BV, Kovacs KT, Laws ER Jr et al (1986) Pathology of invasive pituitary tumors with special reference to functional classification. J Neurosurg 65:733–744
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Bonneville, JF. (2016). Aggressive Pituitary Adenoma. In: MRI of the Pituitary Gland. Springer, Cham. https://doi.org/10.1007/978-3-319-29043-0_10
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DOI: https://doi.org/10.1007/978-3-319-29043-0_10
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