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Atlas and Anatomy of SPECT/CT

  • E. Edmund Kim
  • Hyung-Jun Im
  • Dong Soo Lee
  • Keon Wook Kang
Chapter

Abstract

The successful application of computer algorithms to radiographic imaging in computed tomography (CT) has led to their use to radionuclide technique and to the advent of single-photon emission computed tomography (SPECT), which offers many advantages over two-dimensional planar images. SPECT permits precise three-dimensional (3D) localization of radiopharmaceutical distribution with the possibility of quantification and also cinematic representation of the organ or pathology imaged. It shows improved image contrast and characterizes the pathologic lesion based on CT findings. The hybrid SPECT/CT is capable of performing anatomic and functional imaging sequentially and improves the accuracy of SPECT interpretation, quantifies radiation dosimetry, and leads to improved patient management. Anatomic CT maps facilitate precise localization of the SPECT findings, allow for exclusion of pathology in sites of physiologic tracer uptakes, and can be used for attenuation and scatter correction of the emission data. SPECT is relatively simple to perform, is widely available, allows multiple time-pointed imaging to better study biological processes, and is less expensive than positron emission tomography (PET). SPECT is also expected to have a better spatial contrast resolution using cadmium-zinc-telluride (CZT) multiple detectors.

Keywords

SPECT/CT Oncology Anatomy 

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • E. Edmund Kim
    • 1
  • Hyung-Jun Im
    • 2
  • Dong Soo Lee
    • 1
    • 3
  • Keon Wook Kang
    • 4
  1. 1.Department of Radiological SciencesSchool of Medicine, University of California at IrvineIrvineUSA
  2. 2.Department of Nuclear MedicineSeoul National UniversitySeoulRepublic of Korea
  3. 3.Department of Nuclear Medicine and Department of Molecular Medicine and Biopharmaceutical SciencesSeoul National UniversitySeoulRepublic of Korea
  4. 4.Department of Nuclear Medicine and Cancer Research InstituteSeoul National UniversitySeoulRepublic of Korea

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