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Sleep Disorders in Children pp 405–415Cite as

Childhood Sleep and Medical Disorders

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Abstract

Sleep is an important regulator of growth, metabolism, tissue repair, cell division, endocrine segregation, and immunologic functions. Therefore, many medical disorders are affected by sleep dysfunctions and impact upon sleep quality.

During the first two decades, sleep duration, sleep timing, and sleep characteristics are of utmost importance to an adequate children development being crucial for physical, mental, emotional, and behavioral equilibrium.

A number of medical conditions may give rise to sleep disturbances: asthma and allergies, hematologic diseases, metabolic disorders and obesity, gastrointestinal disorders, including colic and gastroesophageal reflux, chronic pain syndromes, cystic fibrosis, and other orphan genetic diseases.

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References

  1. Li L, Xu Z, Jin X, Yan C, Jiang F, Tong S, Shen X, Li S. Sleep-disordered breathing and asthma: evidence from a large multicentric epidemiological study in China. Respir Res. 2015;16:56.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. CDC report 2015. www.cdc.gov/asthma/asthmadata.htm.

  3. Hanifin JM, Reed ML, Eczema Prevalence and Impact Working Group. A population-based survey of eczema prevalence in the United States. Dermatitis. 2007;18(2):82–91.

    Article  PubMed  Google Scholar 

  4. Teng YK, Chiang LC, Lue KH, Chang SW, Wang L, Lee SP, Ting H, Lee SD. Poor sleep quality measured by polysomnography in non-obese asthmatic children with or without moderate to severe obstructive sleep apnea. Sleep Med. 2014;15(9):1062–7.

    Article  PubMed  Google Scholar 

  5. Brockmann PE, Bertrand P, Castro-Rodriguez JA. Influence of asthma on sleep disordered breathing in children: a systematic review. Sleep Med Rev. 2014;18(5):393–7.

    Article  PubMed  Google Scholar 

  6. Goldstein NA, Aronin C, Kantrowitz B, Hershcopf R, Fishkin S, Lee H, Weaver DE, Yip C, Liaw C, Saadia TA, Abramowitz J, Weedon J. The prevalence of sleep-disordered breathing in children with asthma and its behavioral effects. Pediatr Pulmonol. 2015;50(11):1128–36.

    Article  PubMed  Google Scholar 

  7. Amato JN, Tuon RA, Castelo PM, Gavião MB, Barbosa TS. Assessment of sleep bruxism, orthodontic treatment need, orofacial dysfunctions and salivary biomarkers in asthmatic children. Arch Oral Biol. 2015;60(5):698–705.

    Article  PubMed  Google Scholar 

  8. Shanley LA, Lin H, Flores G. Factors associated with length of stay for pediatric asthma hospitalizations. J Asthma. 2015;52(5):471–7.

    Article  PubMed  Google Scholar 

  9. Yoon HK, Kang SG, Lee HJ, Yoo Y, Choung JT, Seo WH, Kim L. Apnea-related sleep fragmentation and poor vigilance in children with well-controlled asthma. J Sleep Res. 2014;23:189–95.

    Article  Google Scholar 

  10. Koinis-Mitchell D, Kopel SJ, Boergers J, McQuaid EL, Esteban CA, Seifer R, Fritz GK, Beltran AJ, Klein RB, LeBourgeois M. Good sleep health in urban children with asthma: a risk and resilience approach. J Pediatr Psychol. 2015;40(9):888–903.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Evcimik MF, Dogru M, Cirik AA, Nepesov MI. Adenoid hypertrophy in children with allergic disease and influential factors. Int J Pediatr Otorhinolaryngol. 2015;79(5):694–7.

    Article  PubMed  Google Scholar 

  12. van der Mark LB, van Wonderen KE, Mohrs J, van Aalderen WM, ter Riet G, Bindels PJ. Predicting asthma in preschool children at high risk presenting in primary care: development of a clinical asthma prediction score. Prim Care Respir J. 2014;23(1):52–9.

    Article  PubMed  Google Scholar 

  13. Gupta MA, Gupta AK. Sleep-wake disorders and dermatology. Clin Dermatol. 2013;31(1):118–26.

    Article  PubMed  Google Scholar 

  14. Camfferman D, Kennedy JD, Gold M, Simpson C, Lushington K. Sleep and neurocognitive functioning in children with eczema. Int J Psychophysiol. 2013;89(2):265–72.

    Article  PubMed  Google Scholar 

  15. Yamaguchi H, Tada S, Nakanishi Y, Kawaminami S, Shin T, Tabata R, Yuasa S, Shimizu N, Kohno M, Tsuchiya A, Tani K. Association between mouth breathing and atopic dermatitis in Japanese children 2–6 years old: a population-based cross-sectional study. PLoS One. 2015;10(4):e0125916.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Teyhan A, Galobardes B, Henderson J. Child allergic symptoms and mental well-being: the role of maternal anxiety and depression. J Pediatr. 2014;165(3):592–9.e5.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Javaheri S, Storfer-Isser A, Rosen CL, Redline S. Association of short and long sleep durations with insulin sensitivity in adolescents. J Pediatr. 2011;158:617–23.

    Article  PubMed  Google Scholar 

  18. Terán-Pérez G, Arana-Lechuga Y, González-Robles RO, Mandujano M, Santana-Miranda R, Esqueda-Leon E, Calzada R, Ruiz ML, Altamirano N, Sánchez C, Velázquez-Moctezuma J. Polysomnographic features in infants with early diagnosis of congenital hypothyroidism. Brain Dev. 2010;32(4):332–7.

    Article  PubMed  Google Scholar 

  19. Verrillo E, Bizzarri C, Cappa M, Bruni O, Pavone M, Ferri R, Cutrera R. Sleep characteristics in children with growth hormone deficiency. Neuroendocrinology. 2011;94(1):66–74.

    Article  CAS  PubMed  Google Scholar 

  20. Hakim F, Kheirandish-Gozal L, Gozal D. Obesity and altered sleep: a pathway to metabolic derangements in children? Semin Pediatr Neurol. 2015;22(2):77–85.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Hjorth MF, Quist JS, Andersen R, Michaelsen KF, Tetens I, Astrup A, Chaput JP, Sjödin A. Change in sleep duration and proposed dietary risk factors for obesity in Danish school children. Pediatr Obes. 2014;9(6):e156–9.

    Article  CAS  PubMed  Google Scholar 

  22. Thivel D, Isacco L, Aucouturier J, Pereira B, Lazaar N, Ratel S, Doré E, Duché P. Bedtime and sleep timing but not sleep duration are associated with eating habits in primary school children. J Dev Behav Pediatr. 2015;36(3):158–65.

    Article  PubMed  Google Scholar 

  23. Miller AL, Lumeng JC, LeBourgeois MK. Sleep patterns and obesity in childhood. Curr Opin Endocrinol Diabetes Obes. 2015;22(1):41–7.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Katzmarzyk PT, Barreira TV, Broyles ST, Champagne CM, Chaput JP, Fogelholm M, Hu G, Johnson WD, Kuriyan R, Kurpad A, Lambert EV, Maher C, Maia J, Matsudo V, Olds T, Onywera V, Sarmiento OL, Standage M, Tremblay MS, Tudor-Locke C, Zhao P, Church TS, ISCOLE Research Group. Relationship between lifestyle behaviors and obesity in children ages 9–11: results from a 12-country study. Obesity (Silver Spring). 2015;23(8):1696–702.

    Article  Google Scholar 

  25. Kuriyan R, Bhat S, Thomas T, Vaz M, Kurpad AV. Television viewing and sleep are associated with overweight among urban and semi-urban South Indian children. Nutr J. 2007;6:25.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Padez C, Mourao I, Moreira P, Rosado V. Long sleep duration and childhood overweight/obesity and body fat. Am J Hum Biol. 2009;21(3):371–6.

    Article  PubMed  Google Scholar 

  27. Moore M, Kirchner HL, Drotar D, Johnson N, Rosen C, Redline S. Correlates of adolescent sleep time and variability in sleep time: the role of individual and health related characteristics. Sleep Med. 2011;12(3):239–45.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Mitchell JA, Pate RR, España-Romero V, O'Neill JR, Dowda M, Nader PR. Moderate-to-vigorous physical activity is associated with decreases in body mass index from ages 9 to 15 years. Obesity (Silver Spring). 2013;21(3):E280–93.

    Article  CAS  Google Scholar 

  29. Araújo J, Severo M, Ramos E. Sleep duration and adiposity during adolescence. Pediatrics. 2012;130(5):e1146–54.

    Article  PubMed  Google Scholar 

  30. Martinez SM, Tschann JM, Greenspan LC, Deardorff J, Penilla C, Flores E, Pasch LA, Gregorich SE, Butte NF. Is it time for bed? Short sleep duration increases risk of obesity in Mexican American children. Sleep Med. 2014;15(12):1484–9.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Taveras EM, Gillman MW, Peña MM, Redline S, Rifas-Shiman SL. Chronic sleep curtailment and adiposity. Pediatrics. 2014;133(6):1013–22.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Fatima Y, Doi SA, Mamun AA. Longitudinal impact of sleep on overweight and obesity in children and adolescents: a systematic review and bias-adjusted meta-analysis. Obes Rev. 2015;16(2):137–49.

    Article  CAS  PubMed  Google Scholar 

  33. Sijtsma A, Koller M, Sauer PJ, Corpeleijn E. Television, sleep, outdoor play and BMI in young children: the GECKO Drenthe cohort. Eur J Pediatr. 2015;174(5):631–9.

    Article  PubMed  Google Scholar 

  34. Chen G, Ratcliffe J, Olds T, Magarey A, Jones M, Leslie E. BMI, health behaviors, and quality of life in children and adolescents: a school-based study. Pediatrics. 2014;133(4):e868–74.

    Article  PubMed  Google Scholar 

  35. Scharf RJ, DeBoer MD. Sleep timing and longitudinal weight gain in 4- and 5-year-old children. Pediatr Obes. 2015;10(2):141–8.

    Article  CAS  PubMed  Google Scholar 

  36. Plancoulaine S, Lioret S, Regnault N, Heude B, Charles MA, Eden Mother-Child Cohort Study Group. Gender-specific factors associated with shorter sleep duration at age 3 years. J Sleep Res. 2015;24(6):610–20.

    Article  PubMed  Google Scholar 

  37. Berentzen NE, Smit HA, Bekkers MB, Brunekreef B, Koppelman GH, De Jongste JC, Kerkhof M, Van Rossem L, Wijga AH. Time in bed, sleep quality and associations with cardiometabolic markers in children: the Prevention and Incidence of Asthma and Mite Allergy birth cohort study. J Sleep Res. 2014;23(1):3–12.

    Article  PubMed  Google Scholar 

  38. Bonuck K, Chervin RD, Howe LD. Sleep-disordered breathing, sleep duration, and childhood overweight: a longitudinal cohort study. J Pediatr. 2015;166(3):632–9.

    Article  PubMed  Google Scholar 

  39. Kumar Y, Sarvananthan R. GORD in children. BMJ Clin Evid. 2008;2008:0310.

    Google Scholar 

  40. Nelson SP, Chen EH, Syniar GM, Christoffel KK. Prevalence of symptoms of gastroesophageal reflux during infancy. A pediatric practice-based survey. Pediatric Practice Research Group. Arch Pediatr Adolesc Med. 1997;151(6):569–72.

    Article  CAS  PubMed  Google Scholar 

  41. Ramgopal S, Kothare SV, Rana M, Singh K, Khatwa U. Obstructive sleep apnea in infancy: a 7-year experience at a pediatric sleep center. Pediatr Pulmonol. 2014;49(6):554–60.

    Article  PubMed  Google Scholar 

  42. McCormick ME, Sheyn A, Haupert M, Folbe AJ. Gastroesophageal reflux as a predictor of complications after adenotonsillectomy in young children. Int J Pediatr Otorhinolaryngol. 2013;77(9):1575–8.

    Article  PubMed  Google Scholar 

  43. Wasilewska J, Kaczmarski M, Debkowska K. Obstructive hypopnea and gastroesophageal reflux as factors associated with residual obstructive sleep apnea syndrome. Int J Pediatr Otorhinolaryngol. 2011;75(5):657–63.

    Article  PubMed  Google Scholar 

  44. http://www.who.int/mediacentre/factsheets/fs308/en/.

  45. http://www.nhlbi.nih.gov/health/health-topics/topics/sca.

  46. Daniel LC, Grant M, Kothare SV, Dampier C, Barakat LP. Sleep patterns in pediatric sickle cell disease. Pediatr Blood Cancer. 2010;55(3):501–7.

    Article  PubMed  Google Scholar 

  47. Goldstein NA, Keller R, Rey K, Rao S, Weedon J, Dastgir G, Mironov A, Miller ST. Sleep-disordered breathing and transcranial Dopplers in sickle cell disease. Arch Otolaryngol Head Neck Surg. 2011;137(12):1263–8.

    Article  PubMed  Google Scholar 

  48. Rogers VE, Marcus CL, Jawad AF, Smith-Whitley K, Ohene-Frempong K, Bowdre C, Allen J, Arens R, Mason TB. Periodic limb movements and disrupted sleep in children with sickle cell disease. Sleep. 2011;34(7):899–908. Erratum in: Sleep. 2012 Jun;35(6):725.

    Article  PubMed  PubMed Central  Google Scholar 

  49. Tarasiuk A, Abdul-Hai A, Moser A, Freidman B, Tal A, Kapelushnik J. Sleep disruption and objective sleepiness in children with beta-thalassemia and congenital dyserythropoietic anemia. Arch Pediatr Adolesc Med. 2003;157(5):463–8. Erratum in: Arch Pediatr Adolesc Med. 2004 Feb;158(2):110.

    Article  PubMed  Google Scholar 

  50. Sritippayawan S, Norasetthekul S, Nuchprayoon I, Deerojanawong J, Desudchit T, Prapphal N. Obstructive sleep apnea among children with severe beta-thalassemia. Southeast Asian J Trop Med Public Health. 2012;43(1):152–9.

    PubMed  Google Scholar 

  51. Valrie CR, Bromberg MH, Palermo T, Schanberg LE. A systematic review of sleep in pediatric pain populations. J Dev Behav Pediatr. 2013;34(2):120–8.

    Article  PubMed  PubMed Central  Google Scholar 

  52. Lewin DS, Dahl RE. Importance of sleep in the management of pediatric pain. J Dev Behav Pediatr. 1999;20(4):244–52.

    Article  CAS  PubMed  Google Scholar 

  53. Stanford EA, Chambers CT, Biesanz JC, Chen E. The frequency, trajectories and predictors of adolescent recurrent pain: a population-based approach. Pain. 2008;138(1):11–21.

    Article  PubMed  Google Scholar 

  54. Dosi C, Figura M, Ferri R, Bruni O. Sleep and headache. Semin Pediatr Neurol. 2015;22(2):105–12.

    Article  PubMed  Google Scholar 

  55. Braz M, Barros Filho AA, Barros MB. Adolescent health: a population-based study in Campinas, São Paulo State, Brazil. Cad Saude Publica. 2013;29(9):1877–88. Portuguese.

    Article  PubMed  Google Scholar 

  56. Zwart JA, Dyb G, Holmen TL, Stovner LJ, Sand T. The prevalence of migraine and tension-type headaches among adolescents in Norway. The Nord-Trøndelag Health Study (Head-HUNT-Youth), a large population-based epidemiological study. Cephalalgia. 2004;24(5):373–9.

    Article  PubMed  Google Scholar 

  57. Perquin CW, Hazebroek-Kampschreur AA, Hunfeld JA, Bohnen AM, van Suijlekom-Smit LW, Passchier J, van der Wouden JC. Pain in children and adolescents: a common experience. Pain. 2000;87(1):51–8.

    Article  CAS  PubMed  Google Scholar 

  58. Dooley JM, Gordon KE, Wood EP. Self-reported headache frequency in Canadian adolescents: validation and follow-up. Headache. 2005;45(2):127–31.

    Article  PubMed  Google Scholar 

  59. Bellini B, Arruda M, Cescut A, Saulle C, Persico A, Carotenuto M, Gatta M, Nacinovich R, Piazza FP, Termine C, Tozzi E, Lucchese F, Guidetti V. Headache and comorbidity in children and adolescents. J Headache Pain. 2013;14:79.

    Article  PubMed  PubMed Central  Google Scholar 

  60. Paiva T, Gaspar T, Matos MG. Sleep deprivation in adolescents: correlations with health complaints and health-related quality of life. Sleep Med. 2015;16(4):521–7.

    Article  PubMed  Google Scholar 

  61. Sillanpää M, Aro H. Headache in teenagers: comorbidity and prognosis. Funct Neurol. 2000;15 Suppl 3:116–21.

    PubMed  Google Scholar 

  62. Bruni O, Novelli L, Guidetti V, Ferri R. Sleep and headaches during adolescence. Adolesc Med State Art Rev. 2010;21(3):446–56.

    PubMed  Google Scholar 

  63. Paiva T. Sleep and headache. Handb Clin Neurol. 2011;99:1073–86.

    Article  PubMed  Google Scholar 

  64. Esposito M, Parisi P, Miano S, Carotenuto M. Migraine and periodic limb movement disorders in sleep in children: a preliminary case-control study. J Headache Pain. 2013;14:57.

    Article  PubMed  PubMed Central  Google Scholar 

  65. Chang SJ, Chae KY. Obstructive sleep apnea syndrome in children: epidemiology, pathophysiology, diagnosis and sequelae. Korean J Pediatr. 2010;53(10):863–71.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Masuko AH, Villa TR, Pradella-Hallinan M, Moszczynski AJ, Carvalho Dde D, Tufik S, do Prado GF, Coelho FM. Prevalence of bruxism in children with episodic migraine – a case-control study with polysomnography. BMC Res Notes. 2014;7:298.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Shan Z, Deng G, Li J, Li Y, Zhang Y, Zhao Q. How schooling and lifestyle factors effect neck and shoulder pain?: a cross-sectional survey of adolescents in China. Spine (Phila Pa 1976). 2013;222C:34–41.

    Google Scholar 

  68. Haraldstad K, Sørum R, Eide H, Natvig GK, Helseth S. Pain in children and adolescents: prevalence, impact on daily life, and parents’ perception, a school survey. Scand J Caring Sci. 2011;25(1):27–36.

    Article  PubMed  Google Scholar 

  69. Siu YF, Chan S, Wong KM, Wong WS. The comorbidity of chronic pain and sleep disturbances in a community adolescent sample: prevalence and association with sociodemographic and psychosocial factors. Pain Med. 2012;13(10):1292–303.

    Article  PubMed  Google Scholar 

  70. Palermo TM, Fonareva I, Janosy NR. Sleep quality and efficiency in adolescents with chronic pain: relationship with activity limitations and health-related quality of life. Behav Sleep Med. 2008;6(4):234–50.

    Article  PubMed  PubMed Central  Google Scholar 

  71. Tham SW, Holley AL, Zhou C, Clarke GN, Palermo TM. Longitudinal course and risk factors for fatigue in adolescents: the mediating role of sleep disturbances. J Pediatr Psychol. 2013;38(10):1070–80.

    Article  PubMed  PubMed Central  Google Scholar 

  72. Holmberg LI, Hellberg D. Behavioral and other characteristics of relevance for health in adolescents with self-perceived sleeping problems. Int J Adolesc Med Health. 2008;20(3):353–65.

    Article  PubMed  Google Scholar 

  73. Bakker RJ, Sinnema G, Kuis W, van de Putte EM. Exercise in social context contributes to a favourable outcome in fatigued children and adolescents. Arch Dis Child. 2009;94(12):999–1000.

    Article  CAS  PubMed  Google Scholar 

  74. Palermo TM, Kiska R. Subjective sleep disturbances in adolescents with chronic pain: relationship to daily functioning and quality of life. J Pain. 2005;6(3):201–7.

    Article  PubMed  Google Scholar 

  75. Davies S, Crawley E. Chronic fatigue syndrome in children aged 11 years old and younger. Arch Dis Child. 2008;93(5):419–21.

    Article  CAS  PubMed  Google Scholar 

  76. Ablin JN, Buskila D. Predicting fibromyalgia, a narrative review: are we better than fools and children? Eur J Pain. 2014;18(8):1060–6.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. CENC, Sleep Medicine Center, Lisbon, Portugal

    Teresa Paiva MD, PhD

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  1. Teresa Paiva MD, PhD
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Correspondence to Teresa Paiva MD, PhD .

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Editors and Affiliations

  1. Department of Neurology, Charles University and General Teaching Hospital, Prague, Czech Republic

    Soňa Nevšímalová

  2. Sapienza University, S. Andrea Hospital, Department of Developmental and Social Psychology, Rome, Roma, Italy

    Oliviero Bruni

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Paiva, T. (2017). Childhood Sleep and Medical Disorders. In: Nevšímalová, S., Bruni, O. (eds) Sleep Disorders in Children. Springer, Cham. https://doi.org/10.1007/978-3-319-28640-2_18

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  • DOI: https://doi.org/10.1007/978-3-319-28640-2_18

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