Abstract
Sleep and epilepsy are common bedfellows. Sleep influences seizures and epilepsy in terms of frequency and occurrence of interictal spikes and occurrence, timing, and threshold of seizure. On the other hand, epilepsy can worsen sleep architecture and severity of sleep disorders. Thus a vicious cycle is set. Additionally, antiepileptic drugs also influence sleep. So sleep complaints/disorder also should be considered when selecting appropriate antiepileptic drugs. Moreover, sudden unexpected death in epilepsy (SUDEP) occurs in sleep and is most likely associated with cardiorespiratory changes in sleep, occurring ictally or postictally. Furthermore, poor sleep is associated with worsened quality of life, neurocognitive and behavioral functioning, and memory deficits on top of preexisting worsening due to epilepsy itself. Improving sleep and treatment of sleep disorders improve seizure frequency and overall well-being in patients with epilepsy. Hence, sleep evaluation and management are important in patient with epilepsy. In this chapter, we have discussed these interactions.
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Jain, S.V., Kothare, S.V. (2017). Sleep and Epilepsy. In: NevÅ¡Ãmalová, S., Bruni, O. (eds) Sleep Disorders in Children. Springer, Cham. https://doi.org/10.1007/978-3-319-28640-2_15
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