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VNS Therapy for the Treatment of Epilepsy

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Abstract

Vagus nerve stimulation (VNS Therapy) for the treatment of drug resistant epilepsy was CE marked in 1994 and approved in the US in 1997. This chapter will review the history of the treatment, mechanisms of action, and the technology involved, including programming. Efficacy, selection of candidates, initiation of therapy, and maintenance therapy will also be covered. Finally, complications and adverse events, strengths and limitations, and other vagus nerve stimulation devices will be discussed.

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Authors and Affiliations

  1. Cyberonics, Inc., 100 Cyberonics Blvd, Houston, TX, 77058, USA

    Clinton W. Wright PharmD, BCPP

  2. Department of Clinical and Medical Affairs, Cyberonics, Inc., Houston, TX, USA

    Lu Bu BS, MBA

  3. Cyberonics, New Products and Clinical Engineering, Houston, TX, USA

    April Jones BS

  4. Department of Global Medical Affairs, Cyberonics, Houston, TX, USA

    Natasha Calder Green MA, ELS

Authors
  1. Clinton W. Wright PharmD, BCPP
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  2. Lu Bu BS, MBA
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  3. April Jones BS
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  4. Natasha Calder Green MA, ELS
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Corresponding author

Correspondence to Clinton W. Wright PharmD, BCPP .

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Editors and Affiliations

  1. Sheffield Institute for Translational Neuroscience, Department of Neuroscience, Faculty of Medicine, Dentistry & Health, University of Sheffield, Sheffield, South Yorkshire, United Kingdom

    Arshad Majid

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Wright, C.W., Bu, L., Jones, A., Calder Green, N. (2017). VNS Therapy for the Treatment of Epilepsy. In: Majid, A. (eds) Electroceuticals. Springer, Cham. https://doi.org/10.1007/978-3-319-28612-9_8

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