Stem Cells for the Prevention of Bronchopulmonary Dysplasia

  • Won Soon ParkEmail author
Part of the Respiratory Medicine book series (RM)


Bronchopulmonary dysplasia (BPD), a chronic lung disease that occurs in very premature infants, is a major cause of mortality and long-term morbidities in premature infants. Several studies have indicated that stem cell therapy is a promising novel therapeutic modality in preventing and/or treating BPD. This review summarizes recent advances in stem cell research for treating BPD, with a particular focus on preclinical data, covering important issues for clinical translation such as optimal cell type, route, dose, and timing of stem cell therapy and summarizing the results of successful phase I clinical trials of stem cell therapies for BPD.


Bronchopulmonary dysplasia Mesenchymal stem cells Cell transplantation Infant Premature 


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of PediatricsSungkyunkwan University School of Medicine, Samsung Medical CenterKangnam Gu, SeoulSouth Korea

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