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Modulatory Effects of Dietary Amino Acids on Neurodegenerative Diseases

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The Benefits of Natural Products for Neurodegenerative Diseases

Part of the book series: Advances in Neurobiology ((NEUROBIOL,volume 12))

Abstract

Proteins are playing a vital role in maintaining the cellular integrity and function, as well as for brain cells. Protein intake and supplementation of individual amino acids can affect the brain functioning and mental health, and many of the neurotransmitters in the brain are made from amino acids. The amino acid supplementation has been found to reduce symptoms, as they are converted into neurotransmitters which in turn extenuate the mental disorders. The biosynthesis of amino acids in the brain is regulated by the concentration of amino acids in plasma. The brain diseases such as depression, bipolar disorder, schizophrenia, obsessive-compulsive disorder (OCD), and Alzheimer’s (AD), Parkinson’s (PD), and Huntington’s diseases (HD) are the most common mental disorders that are currently widespread in numerous countries. The intricate biochemical and molecular machinery contributing to the neurological disorders is still unknown, and in this chapter, we revealed the involvement of dietary amino acids on neurological diseases.

An erratum to this chapter can be found at http://dx.doi.org/10.1007/978-3-319-28383-8_24

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Authors and Affiliations

  1. Department of Zoology, Nizam College, Hyderabad, India

    Senthilkumar Rajagopal Ph.D., Supraj Raja Sangam, Shubham Singh & Venkateswara Rao Joginapally

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  1. Senthilkumar Rajagopal Ph.D.
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  2. Supraj Raja Sangam
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  3. Shubham Singh
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  4. Venkateswara Rao Joginapally
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Correspondence to Senthilkumar Rajagopal Ph.D. .

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Editors and Affiliations

  1. Food Science and Nutrition College of Agricultural and Marine Sciences, Sultan Qaboos University, Muscat, Oman

    M. Mohamed Essa

  2. National Institutes of Health, National Institute on Alcohol Abuse, Rockville, Maryland, USA

    Mohammed Akbar

  3. Australian School of Advanced Medicine, Macquarie University, Sydney, New South Wales, Australia

    Gilles Guillemin

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Rajagopal, S., Sangam, S.R., Singh, S., Joginapally, V.R. (2016). Modulatory Effects of Dietary Amino Acids on Neurodegenerative Diseases. In: Essa, M., Akbar, M., Guillemin, G. (eds) The Benefits of Natural Products for Neurodegenerative Diseases. Advances in Neurobiology, vol 12. Springer, Cham. https://doi.org/10.1007/978-3-319-28383-8_22

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