Mathematical Modelling of Radiobiological Parameters

  • Piernicola Pedicini
  • Lidia StrigariEmail author
  • Luigi Spiazzi
  • Alba Fiorentino
  • Paolo Tini
  • Luigi Pirtoli
Part of the Current Clinical Pathology book series (CCPATH)


All treatment strategies are studied at the preclinical and clinical level, and the related endpoints are used to extract radiobiological parameters in mathematical models. This chapter aims to provide an overview of these approaches based on clinical and cellular data.


Glioma Cell Radiation Response Biological Effective Dose Clonogenic Cell Tumour Control Probability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Piernicola Pedicini
    • 1
  • Lidia Strigari
    • 2
    Email author
  • Luigi Spiazzi
    • 3
  • Alba Fiorentino
    • 4
  • Paolo Tini
    • 5
    • 6
  • Luigi Pirtoli
    • 5
    • 7
  1. 1.I.R.C.C.S. Regional Cancer Hospital C.R.O.B.Rionero-in-VulturePZItaly
  2. 2.Laboratory of medical physics and expert systemsRegina Elena National Cancer InstituteRomeItaly
  3. 3.Physics DepartmentSpedali Civili HospitalBresciaItaly
  4. 4.Sacro Cuore Don Calabria HospitalNegrar-VeronaItaly
  5. 5.Tuscany Tumor InstituteFlorenceItaly
  6. 6.Unit of Radiation OncologyUniversity Hospital of Siena (Azienda Ospedaliera-Universitaria Senese)SienaItaly
  7. 7.Unit of Radiation Oncology, Department of Medicine, Surgery and NeurosciencesUniversity of SienaSienaItaly

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