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NanoMaterials Technology for Research Radiobiology

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Radiobiology of Glioblastoma

Part of the book series: Current Clinical Pathology ((CCPATH))

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Abstract

Advances in nanoscience and nanotechnology have notably improved the field of oncology in terms of cancer diagnosis and therapy. Recently, there is a great interest in developing multifunctional systems for theranostic approaches within a single formulation, which is able to combine detection, treatment, monitoring, and image-guided interventions, allowing a real-time monitoring drug delivery, release, and efficacy. NanoMaterials (NMs), such as liposomes, dendrimers, quantum dots, iron oxide-, metallic-, and magnetic-nanoparticles (NPs), perfluorocarbon and carbon nanotubes, delivering anticancer radioisotopes, are a suitable radionanomedicine theranostic system. This chapter provides an overview on NMs exploitable in cancer radio-therapy and imaging, highlighting the emerging possibilities of theranostic nanomedicines in cancer cure. The current NMs platforms for future clinical application with regard to imaging and treatment of glioblastoma, one of the most deadly diseases characterized by high resistance to chemotherapy and radiotherapy, will be discussed.

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Author information

Authors and Affiliations

  1. Department of Biological and Environmental Science and Technology (Di.S.Te.B.A.), University of Salento, Prov. le Lecce-Monteroni, Lecce, 73100, Italy

    Elisa Panzarini & Luciana Dini

Authors
  1. Elisa Panzarini
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  2. Luciana Dini
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Correspondence to Luciana Dini .

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Editors and Affiliations

  1. University of Siena, Sec. of Radiation Oncology,Dept. of Med., Siena, Italy

    Luigi Pirtoli

  2. Dept. of Applied Clinical & Biotech Sci., University of L’Aquila, L’Aquila, Italy

    Giovanni Luca Gravina

  3. Department of Biology, Temple University, Philadelphia, Pennsylvania, USA

    Antonio Giordano

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Panzarini, E., Dini, L. (2016). NanoMaterials Technology for Research Radiobiology. In: Pirtoli, L., Gravina, G., Giordano, A. (eds) Radiobiology of Glioblastoma. Current Clinical Pathology. Humana Press, Cham. https://doi.org/10.1007/978-3-319-28305-0_15

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  • DOI: https://doi.org/10.1007/978-3-319-28305-0_15

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  • Publisher Name: Humana Press, Cham

  • Print ISBN: 978-3-319-28303-6

  • Online ISBN: 978-3-319-28305-0

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