Abstract
Brain vascular malformations (excluding dural arteriovenous fistulas) are mostly congenital lesions that are less common than cerebral aneurysms but also cause serious disabilities or death in a significant proportion of affected patients.
The group of lesions called “brain vascular malformations” is a heterogeneous one, clinically, histologically, and in terms of imaging. High-flow lesions such as arteriovenous malformations and slow-flow lesions such as cavernous malformations are included in this group.
Clinical manifestations range from headaches, seizures, to focal deficits due to intracranial hemorrhages. CT and CTA are commonly the first diagnostic modalities used in these patients, and MRI and MRA help in the diagnosis of smaller lesions and are helpful in surgical planning. Digital subtraction angiography is the gold standard for evaluation of arterial and venous malformations, allowing higher spatial and temporal resolution and also detailed evaluation before endovascular or surgical treatments.
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References
McCormick WF. The pathology of vascular (“arteriovenous”) malformations. J Neurosurg. 1966;24(4):807–16.
Moussa R, Wong J, Awad I. Pathology and genetic factors. In Stieg P, Batjer HH, Samson D. Intracranial arteriovenous malformations. 1st ed, New York: Informa Healthcare USA, Inc; 2007. p. 21–6.
Berenstein AL, Pierre, Brugge K. Cerebral vascular malformations: incidence, classification, angioarchitecture and symptomatology of brain arteriovenous and venous malformations. In: Surgical neuroangiography. Springer-Verlag Berlin Heilderberg NewYork; 2004. p. 609–94.
Lowe LH, Marchant TC, Rivard DC, Scherbel AJ. Vascular malformations: classification and terminology the radiologist needs to know. Semin Roentgenol. 2012;47(2):106–17.
Osborn AG. Osborn’s brain: imaging, pathology, and anatomy. 1st ed. Salt Lake City: Amirsys; 2013. xi, 1272 p.
Zimmer A, Hagen T, Ahlhelm F, Viera J, Reith W, Schulte-Altedorneburg G. Developmental venous anomaly (DVA). Radiologe. 2007;47(10):868. 70–4.
Hsu F, Rigamonti D, Huhn SL. Chapter 2 - Epidemiology of cavernous malformations. In Awad IA, Barrow DL. Cavernous malformations. Park Ridge - Illinois, USA: AANS Publications Comittee; 1993. p. 13–4.
Carpenter JS, Rosen CL, Bailes JE, Gailloud P. Sinus pericranii: clinical and imaging findings in two cases of spontaneous partial thrombosis. AJNR Am J Neuroradiol. 2004;25(1):121–5.
Mohr JP, Parides MK, Stapf C, Moquete E, Moy CS, Overbey JR, et al. Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial. Lancet. 2014;383(9917):614–21.
Geibprasert S, Pongpech S, Jiarakongmun P, Shroff MM, Armstrong DC, Krings T. Radiologic assessment of brain arteriovenous malformations: what clinicians need to know. Radiographics: Rev Publ Radiol Soc N Am Inc. 2010;30(2):483–501.
Albright L, Pollack I, Adelson D. Principles and practice of pediatric neurosurgery. 3rd ed. Stuttgart: Georg Thieme Verlag; 2015.
Kortman HG, Smit EJ, Oei MT, Manniesing R, Prokop M, Meijer FJ. 4D-CTA in neurovascular disease: a review. AJNR Am J Neuroradiol. 2015;36(6):1026–33.
Taschner CA, Gieseke J, Le Thuc V, Rachdi H, Reyns N, Gauvrit JY, et al. Intracranial arteriovenous malformation: time-resolved contrast-enhanced MR angiography with combination of parallel imaging, keyhole acquisition, and k-space sampling techniques at 1.5 T. Radiology. 2008;246(3):871–9.
Spetzler RF, Martin NA. A proposed grading system for arteriovenous malformations. J Neurosurg. 1986;65(4):476–83.
Yun TJ, Na DG, Kwon BJ, Rho HG, Park SH, Suh YL, et al. A T1 hyperintense perilesional signal aids in the differentiation of a cavernous angioma from other hemorrhagic masses. AJNR Am J Neuroradiol. 2008;29(3):494–500.
Greenberg M. Handbook of neurosurgery. 7th ed. New York: Thieme. Greenberg Graphics, Inc.Tampa Florida; 2010. 1352 p.
Atlas SW. Magnetic resonance imaging of the brain and spine. 4th ed. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2009.
Spetzler RF, Kondziolka D, Higashida RT, Kalani Y. Comprehensive management of arteriovenous malformations of the brain and spine. Available from: http://libproxy.lib.unc.edu/login?url=http://dx.doi.org/10.1017/CBO9781139523943.
International Radiosurgery Association. Stereoatactic radiosurgery for patients with intracranial arteriovenous malformations. Radiosurgery practice guideline report. 2009.
Blauwblomme T, Naggara O, Brunelle F, Grevent D, Puget S, Di Rocco F, et al. Arterial spin labeling magnetic resonance imaging: toward noninvasive diagnosis and follow-up of pediatric brain arteriovenous malformations. J Neurosurg Pediatr. 2015;15(4):451–8.
Gross BA, Lin N, Du R, Day AL. The natural history of intracranial cavernous malformations. Neurosurg Focus. 2011;30(6):E24.
Iv M, Fischbein NJ, Zaharchuk G. Association of developmental venous anomalies with perfusion abnormalities on arterial spin labeling and bolus perfusion-weighted imaging. J Neuroimaging: Off J Am Soc Neuroimaging. 2015;25(2):243–50.
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Jacinto, J.M., Fragata, I.R. (2016). Brain Vascular Malformations. In: Hoffmann Nunes, R., Abello, A., Castillo, M. (eds) Critical Findings in Neuroradiology. Springer, Cham. https://doi.org/10.1007/978-3-319-27987-9_9
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DOI: https://doi.org/10.1007/978-3-319-27987-9_9
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