Abstract
In this paper, we present a multi-atlas segmentation method based on the level set formulation for performing label fusion that takes into account the image information and regularity of the region of interest (ROI). In the presented method, multiple atlases are first registered to a target image by deformable registration via attribute matching and mutual saliency weighting (DRAMMS) and advanced neuroimaging tools (ANTs) to get the warped labels. Then, an optimal labeling is sought by label fusion for segmentation of target image. Label fusion is achieved by seeking an optimal level set function which minimizes an energy functional in regards to three terms: label fusion term, image based term, and regularization term. In this work, we discussed the impact of subset on the accuracy of segment results. Results show that segmentation results will be much more accurate if an appropriate subset of atlases are selected for each target image than those given by non-selective combination of random atlas subsets.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Isgum, I., Staring, M., Rutten, A., Prokop, M., Viergever, M.A., van Ginneken, B.: Multi-atlas-based segmentation with local decision fusion-application to cardiac and aortic segmentation in CT scans. IEEE Trans. Imag. Proc. 28(7), 1000–1010 (2009)
Lötjönen, J.M.P., Wolz, R., Koikkalainen, J.R., et al.: Fast and robust multi-atlas segmentation of brain magnetic resonance images. Neuroimage 49(3), 2352–2365 (2010)
Van Rikxoort, E.M., et al.: Adaptive local multi-atlas segmentation: application to the heart and the caudate nucleus. Med. Image Anal. 14(1), 39–49 (2010)
Wang, H., et al.: Regression-based label fusion for multi-atlas segmentation. In: 2011 IEEE Conference on Computer Vision and Pattern Recognition (CVPR). IEEE (2011)
Gholipour, A., Akhondi-Asl, A., et al.: Multi-atlas multi-shape segmentation of fetal brain MRI for volumetric and morphometric analysis of ventriculomegaly. Neuroimage 60(3), 1819–1831 (2012)
Aljabar, P., Heckemann, R.A., Hammers, A., Hajnal, J.V., Rueckert, D.: Multi-atlas based segmentation of brain images: atlas selection and its effect on accuracy. Neuroimage 46(3), 726–738 (2009)
Asman, A.J., Landman, B.A.: Non-local statistical label fusion for multi-atlas segmentation. Med. Image Anal. 17(2), 194–208 (2013)
Artaechevarria, X., Arrate, M.B., Ortiz-de-Solórzano, C.: Combination strategies in multi-atlas image segmentation: application to brain MR data. IEEE Trans. Med. Imaging 28(8), 1266–1277 (2009)
Warfield, S.K., Zou, K.H., Wells, W.M.: Simultaneous truth and performance level estimation (STAPLE): an algorithm for the validation of image segmentation. IEEE Trans. Med. Imaging 23(7), 903–921 (2004)
Ou, Y., et al.: DRAMMS: deformable registration via attribute matching and mutual-saliency weighting. Med. Image Anal. 15(4), 622–639 (2011)
Avants, B.B., Tustison, N.J., Song, G., Cook, P.A., Klein, A., Gee, J.C.: A reproducible evaluation of ants similarity metric performance in brain image registration. Neuroimage 54(3), 2033–2044 (2011)
Li, C., Kao, C., Gore, J.C., et al.: Minimization of region-scalable fitting energy for image segmentation. IEEE Trans. Image Process. 17(10), 1940–1949 (2008)
Feng, C., Li, C., Zhao, D., Davatzikos, C., Litt, H.: Segmentation of the left ventricle using distance regularized two-layer level set approach. In: Mori, K., Sakuma, I., Sato, Y., Barillot, C., Navab, N. (eds.) MICCAI 2013, Part I. LNCS, vol. 8149, pp. 477–484. Springer, Heidelberg (2013)
Acknowledgment
This research was partly supported by National Natural Science Foundation of China (NSFC) under Grant No. 61302012 and No. 61172002, the Fundamental Research Funds for the Central Universities under Grant N130418002, N120518001, N140403006 and N140402003. The National Key Technology support Program 2014BAI17B02, and Liaoning Natural Science Foundation under Grant No. 2013020021.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this paper
Cite this paper
Song, Y., Gong, Z., Zhao, D., Feng, C., Li, C. (2015). Impact of the Number of Atlases in a Level Set Formulation of Multi-atlas Segmentation. In: Bebis, G., et al. Advances in Visual Computing. ISVC 2015. Lecture Notes in Computer Science(), vol 9474. Springer, Cham. https://doi.org/10.1007/978-3-319-27857-5_48
Download citation
DOI: https://doi.org/10.1007/978-3-319-27857-5_48
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-27856-8
Online ISBN: 978-3-319-27857-5
eBook Packages: Computer ScienceComputer Science (R0)