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Abstract

Tumor microenvironment plays an important role in the initiation and progression of tumors. Studies on neoplastic transformation have focused on events that occur within tumor cells, and have addressed the microenvironment of tumor cells documenting its importance in supporting tumor progression. Before metastatic dissemination, primary tumors secrete factors that contribute to the development of a pre-metastatic niche, rendering the microenvironment more receptive to tumor growth.

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Ribatti, D. (2016). Tumor Microenvironment. In: The Role of Microenvironment in the Control of Tumor Angiogenesis. Springer, Cham. https://doi.org/10.1007/978-3-319-27820-9_1

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