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Encapsulation by Hydrogen-Bonded and Other Supramolecular Capsules

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The Encapsulation Phenomenon

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Abstract

Most of the supramolecular capsules are neutral compounds that are self-assembled by hydrogen bonding between complementary organic ligand syntones to form unimolecular, dimeric, tetrameric, or hexameric hydrogen-bonded cage frameworks. In several cases, electrostatic (Coulombic) and stacking interactions have been used for self-assembly of the corresponding supramolecular capsules. The template effect of encapsulated species (mostly of neutral guests or co-guests) has been observed in many systems. Moreover, co-encapsulation of various guests caused the specific types of stereoisomerism (so-called social isomerism and isomeric (diastereomeric) constellation, see Sect. 3.1.1) to appear, which are characteristic of these “soft” capsules. Another important feature of these capsules is the so-called Rebek’s rule postulating the encapsulation to proceed efficiently at the packing coefficient of the guest of approximately 55 % (see below).

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Authors and Affiliations

  1. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences and Gubkin Russian State University of Oil and Gas, Moscow, Russia

    Yan Voloshin

  2. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Moscow, Russia

    Irina Belaya

  3. Anorganisch Chemisches Institut Ruprecht-Karls-Univers. Heidelberg, Heidelberg, Germany

    Roland Krämer

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  1. Yan Voloshin
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  2. Irina Belaya
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  3. Roland Krämer
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Voloshin, Y., Belaya, I., Krämer, R. (2016). Encapsulation by Hydrogen-Bonded and Other Supramolecular Capsules. In: The Encapsulation Phenomenon. Springer, Cham. https://doi.org/10.1007/978-3-319-27738-7_3

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