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Management of Acute Diabetic Fractures of the Ankle

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Book cover The Surgical Management of the Diabetic Foot and Ankle

Abstract

Ankle fractures are so commonly seen and routinely treated that we fail to remember that the diabetic patient also presents with impaired healing of the wound and bone, vascular insufficiency, and neuropathy. This is because chronic hyperglycemia increases osteoclastic activity, decreases osteoblastic activity, impairs the ability of the red blood cell to deliver oxygen, and decreases the ability of fibroblasts from migrating and attaching to wounds. Overall, the incidence of adult ankle fractures is 100.8/100,000/per year with approximately 260,000 Americans per year sustaining an ankle, six percent of which are diabetics. Preoperatively, patients should have good neurovascular examinations along with an evaluation of their hemoglobin A1c. Preoperative evaluation combined with surgical techniques, specific for the diabetic pathology, is presented to provide optimal patient outcome for this patient population. Non-operative treatment is indicated for non-displaced fractures. All displaced fractures should be managed surgically with four options available: standard fixation, trans-syndesmotic, trans-articular or a combined technique. Major complications associated with managing these patients consist of failure of fixation, skin and wound problems, infections and the development of Charcot neuroarthropathy.

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References

  1. Vincent AM, Russell JW, Low P, Feldman EL. Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr Rev. 2004;25:612–28.

    Article  CAS  PubMed  Google Scholar 

  2. Paraskevas KI, Baker DM, Pompella A, Mikhailidis DP. Does diabetes mellitus play a role in restenosis and patency rates following lower extremity peripheral arterial revascularization? A critical overview. Ann Vasc Surg. 2008;22:481–91.

    Article  PubMed  Google Scholar 

  3. Stadelmann WK, Digenis AG, Tobin GR. Impediments to wound healing. Am J Surg. 1998;176(2A Suppl):39S–47.

    Article  CAS  PubMed  Google Scholar 

  4. Macey LR, Kana SM, Jingushi S, Terek RM, Borretos J, Bolander ME. Defects of early fracture-healing in experimental diabetes. J Bone Joint Surg Am. 1989;71:722–33.

    CAS  PubMed  Google Scholar 

  5. Weinberg E, Maymon T, Moses O, Weinreb M. Streptozotocin-induced diabetes in rats diminishes the size of the osteoprogenitor pool in bone marrow. Diabetes Res Clin Pract. 2014;103:35–41.

    Article  CAS  PubMed  Google Scholar 

  6. Loder RT. The influence of diabetes mellitus on the healing of closed fractures. Clin Orthop Relat Res. 1988;232:210–6.

    PubMed  Google Scholar 

  7. Boddenberg U. Healing time of foot and ankle fractures in patients with diabetes mellitus: literature review and report on own cases. Zentralbl Chir. 2004;129:453–9.

    Article  CAS  PubMed  Google Scholar 

  8. Ganesh SP, Pietrobon R, Cecílio WAC, Pan D, LightdaleN NJA. The impact of diabetes on patient outcomes after ankle fracture. J Bone Joint Surg Am. 2005;87:1712–8.

    Article  PubMed  Google Scholar 

  9. Flynn JM, Rodriguez-del Río F, Pizá PA. Closed ankle fractures in the diabetic patient. Foot Ankle Int. 2000;21:311–9.

    CAS  PubMed  Google Scholar 

  10. Carnevale V, Romagnoli E, D’Erasmo E. Skeletal involvement in patients with diabetes mellitus. Diabetes Metab Res Rev. 2004;20:196–204.

    Article  PubMed  Google Scholar 

  11. Jones KB, Maiers-Yeldon KA, Marsh JL, Zimmerman MB, Estin M, Saltzman CL. Ankle fractures in patients with diabetes mellitus. J Bone Joint Surg Br. 2005;87:489–95.

    Article  CAS  PubMed  Google Scholar 

  12. Centers for Disease Control and Prevention. National Diabetes Statistics Report: Estimates of Diabetes and Its Burden in the United States. Atlanta, GA: U.S. Department of Health and Human Services; 2014. http://www.cdc.gov/diabetes/pubs/statsreport14/national-diabetes-report-web.pdf.

    Google Scholar 

  13. Clark JL, Meiris DC. Building bridges: integrative solutions for managing complex comorbid conditions. Am J Med Qual. 2007;22:5–15.

    Article  Google Scholar 

  14. Ong KL, Cheung BM, Wong LY, Wat NM, Tan KC, Lam KS. Prevalence, treatment, and control of diagnosed diabetes in the U.S. National Health and Nutrition Examination Survey 199-2004. Ann Epidemiol. 2008;18:222–9.

    Article  PubMed  Google Scholar 

  15. Court-Brown CM, Caesar B. Epidemiology of adult fractures: a review. Injury. 2006;37:691–7.

    Article  PubMed  Google Scholar 

  16. Herbst SA, Jones KB, Saltzman CL. Pattern of diabetic neuropathic arthropathy associated with peripheral bone mineral density. J Bone Joint Surg Br. 2004;86:378–83.

    Article  CAS  PubMed  Google Scholar 

  17. Prisk VR, Wukich DK. Ankle fractures in diabetics. Foot Ankle Clin N Am. 2006;11:849863.

    Article  Google Scholar 

  18. Smieja M, Hunt DL, Edelman D, Etchells E, Cornuz J, Simel DL. Clinical examination for the detection of protective sensation in the feet of diabetic patients. International Cooperative Group for Clinical Examination Research. J Gen Intern Med. 1999;14:418–24.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Pham H, Armstrong DG, Harvey C, Harkless LB, Giurini JM, Veves A. Screening techniques to identify people at high risk for diabetic foot ulceration: a prospective multicenter trial. Diabetes Care. 2000;23:606–11.

    Article  CAS  PubMed  Google Scholar 

  20. Wukich DK, Lowery NJ, McMillen RI, Fryberg RG. Postoperative infection rates in foot and ankle surgery: a comparison of patients with and without diabetes mellitus. J Bone Joint Surg Am. 2010;92:287–95.

    Article  PubMed  Google Scholar 

  21. Novo S. Classification, epidemiology, risk factors, and natural history of peripheral artery disease. Diabetes Obes Metab. 2002;4 Suppl 2:S1–6.

    Article  PubMed  Google Scholar 

  22. American Diabetes Association. Peripheral arterial disease in people with diabetes. Diabet Care. 2003;26:3333–41.

    Article  Google Scholar 

  23. Høyer C, Sandermann J, Petersen LJ. The toe-brachial index in the diagnosis of peripheral artery disease. J Vasc Surg. 2013;58:231–8.

    Article  PubMed  Google Scholar 

  24. Liu J, Ludwig T, Ebraheim NA. Effect of the blood HbA1c level on surgical treatment outcomes of diabetics with ankle fractures. Orthop Surg. 2013;5:203–8.

    Article  PubMed  Google Scholar 

  25. Wukich DK, Crim BE, Frykberg RG, Rosario BL. Neuropathy and poorly controlled diabetes increase the rate of surgical site infection after foot and ankle surgery. J Bone Joint Surg Am. 2014;96:832–9.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Hoogwerf BJ, Sferra J, Bonley BG. Diabetes mellitus—overview. Foot Ankle Clin N Am. 2006;11:703–15.

    Article  Google Scholar 

  27. Chaudhary SB, Liporace FA, Gandhi A, Donley BG, Pinzur MS, Lin SS. Complications of ankle fractures in patients with diabetes. J Am Acad Orthop Surg. 2008;16:159–70.

    Article  PubMed  Google Scholar 

  28. Wukich DK, Kline AJ. Current concepts review. The management of ankle fractures in patients with diabetes. J Bone Joint Surg Am. 2008;90:1570–8.

    Article  PubMed  Google Scholar 

  29. McCormack RG, Leith JM. Ankle fractures in diabetics. Complications of surgical management. J Bone Joint Surg Br. 1998;80:689–92.

    Article  CAS  PubMed  Google Scholar 

  30. Jani MM, Ricci WM, Borrelli Jr J, Barrett SE, Johnson JE. A protocol for treatment of unstable ankle fractures using transarticular fixation in patients with diabetes mellitus and loss of protective sensation. Foot Ankle Int. 2003;24:838–44.

    PubMed  Google Scholar 

  31. Bozic V, Thordarson DB, Hertz J. Ankle fusion for definitive management of non-reconstructable pilon fractures. Foot Ankle Int. 2008;29:914–8.

    Article  PubMed  Google Scholar 

  32. SooHoo NF, Krenek L, Eagen MJ, Gurbani B, Ko CY, Zingmond DS. Complication rates following open reduction and internal fixation of ankle fractures. J Bone Joint Surg Am. 2009;91:1042–9.

    Article  PubMed  Google Scholar 

  33. Blotter RH, Connolly E, Wasan A, Chapman MW. Acute complications in the operative treatment of isolated ankle fractures in patients with diabetes mellitus. Foot Ankle Int. 1999;20:687–94.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Dolfi Herscovici Jr. D.O. .

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© 2016 Springer International Publishing Switzerland

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Herscovici, D., Scaduto, J.M. (2016). Management of Acute Diabetic Fractures of the Ankle. In: Herscovici, Jr., D. (eds) The Surgical Management of the Diabetic Foot and Ankle. Springer, Cham. https://doi.org/10.1007/978-3-319-27623-6_8

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  • DOI: https://doi.org/10.1007/978-3-319-27623-6_8

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-27621-2

  • Online ISBN: 978-3-319-27623-6

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