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Neurostimulation for the Management of Failed Back Surgery Syndrome (FBSS)

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Surgery of the Spine and Spinal Cord
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Abstract

The term failed back surgery syndrome (FBSS) is commonly used to describe patients who have ongoing chronic pain after surgery of the lumbar spine. Patients present with persisting spinal (low back or cervical) pain that may or may not radiate into the limb. This denomination is not correct. It feeds the impression as if spine surgery has not been carried out properly. After spine surgery, approximately 30 % of patients continue to have disabling postoperative persistent or recurrent back pain, with or without leg pain. This may be due to a lot of factors, but mainly due to improper surgery or to the FBSS. The correct description of FBSS has been postulated by Kumar et al. in 1998: “persistent or recurrent back and leg pain after lumbar spinal surgery where no indication of macroscopic pathology justifying re-operation can be demonstrate”. As such FBSS is not the same as unsuccessful surgery. The reasons for unsuccessful surgery are mostly a lack of correct diagnosis, incorrect surgical technique, and an important psychosocial distress of the patient (see also Chap. 23). FBSS can only be the result of spine surgery based on a proper diagnosis, executed correctly in a psychologically non-disturbed patient. Although in case of FBSS patients, the exact cause of the pain is commonly unknown, its nature is usually that of a neuropathic pain, often with peripheral and/or central sensitization (see also Chap. 22). The pain can be in the lower back (or cervical region) but is predominantly in the extremities. It is believed that the cause of FBSS is an intrinsic radiculopathy (peripheral sensitization) of a properly decompressed nerve root. Neuropathic low back pain is probably mainly the result of new but pathologic innervation of the disc, which runs concomitant with its (neo)vascularization upon degeneration or post-discectomy.

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References

  1. North RB, Ewend MG, Lawton MT, Kidd DH, Piantadosi S (1991) Failed back surgery syndrome: 5-year follow-up after spinal cord stimulator implantation. Neurosurgery 28:692–699

    Article  CAS  PubMed  Google Scholar 

  2. Segal R, Stacey BR, Rudy TE, Baser S, Markham J (1998) Spinal cord stimulation revisited. Neurol Res 20:391–396

    CAS  PubMed  Google Scholar 

  3. Waddell G, Kummel EG, Lotto WN, Graham JD, Hall H, McCulloch JA (1979) Failed lumbar disc surgery and repeat surgery following industrial injuries. J Bone Joint Surg Am 61:201–207

    CAS  PubMed  Google Scholar 

  4. North RB, Campbell JN, James CS, Conover-Walker MK, Wang H, Piantadosi S, Rybock JD, Long DM (1991) Failed back surgery syndrome: 5-year follow-up in 102 patients undergoing repeated operation. Neurosurgery 28:685–690; discussion 690–681

    Article  CAS  PubMed  Google Scholar 

  5. North RB, Kidd DH, Farrokhi F, Piantadosi SA (2005) Spinal cord stimulation versus repeated lumbosacral spine surgery for chronic pain: a randomized, controlled trial. Neurosurgery 56:98–106; discussion 106–107

    PubMed  Google Scholar 

  6. Kumar K, Toth C (1998) The role of spinal cord stimulation in the treatment of chronic pain postlaminectomy. Curr Rev Pain 2:85–85

    Article  Google Scholar 

  7. Wiesenfeld-Hallin Z, Aldskogius H, Grant G, Hao JX, Hokfelt T, Xu XJ (1997) Central inhibitory dysfunctions: mechanisms and clinical implications. Behav Brain Sci 20:420–425; discussion 435–513

    CAS  PubMed  Google Scholar 

  8. Ohnmeiss DD, Rashbaum RF (2001) Patient satisfaction with spinal cord stimulation for predominant complaints of chronic, intractable low back pain. Spine J 1:358–363

    Article  CAS  PubMed  Google Scholar 

  9. Bosscher HA, Heavner JE (2010) Incidence and severity of epidural fibrosis after back surgery: an endoscopic study. Pain Pract 10:18–24

    Article  PubMed  Google Scholar 

  10. Anderson SR (2000) A rationale for the treatment algorithm of failed back surgery syndrome. Curr Rev Pain 4:395–406

    Article  CAS  PubMed  Google Scholar 

  11. Borenstein D (1998) Epidemiology, etiology, diagnostic evaluation, and treatment of low back pain. Curr Opin Rheumatol 10:104–109

    Article  CAS  PubMed  Google Scholar 

  12. Bigos S, Müller G (2000) Primary care approach to acute and chronic back problems: definitions and care. In: Loeser JD (ed) Bonica’s management of pain, 3rd edn. Lippincott, Williams and Wilkins, London, pp 1549–1528

    Google Scholar 

  13. Onesti ST (2004) Failed back syndrome. Neurologist 10:259–264

    Article  PubMed  Google Scholar 

  14. Block A (2000) Psychological screening of spine surgery candidates: risk factors for poor outcome. In: Loeser JD (ed) Bonica’s management of pain, 3rd edn. Lippincott, Williams and Wilkins, London, pp 1509–1557

    Google Scholar 

  15. Voorhies RM, Jiang X, Thomas N (2007) Predicting outcome in the surgical treatment of lumbar radiculopathy using the pain drawing score, McGill short form pain questionnaire, and risk factors including psychosocial issues and axial joint pain. Spine J 7:516–524

    Article  PubMed  Google Scholar 

  16. Baron R (2006) Mechanisms of disease: neuropathic pain – a clinical perspective. Nat Clin Pract Neurol 2:95–106

    Article  PubMed  Google Scholar 

  17. Linderoth B, Foreman R (2006) Mechanisms of spinal cord stimulation in painful syndromes. Role of animal models. Pain Med 7:14–26

    Article  Google Scholar 

  18. Vaccaro AR, Silber JS (2001) Post-traumatic spinal deformity. Spine (Phila Pa 1976) 26:S111–S118

    Article  CAS  Google Scholar 

  19. Linderoth B (2000) Mechanisms of action of spinal cord stimulation in complex regional pain syndromes: present state of research and the future. In: Krames ES, Reig E (eds) Worldwide pain conference management of acute and chronic pain. Monduzzi Editore, Bologna, pp 621–628

    Google Scholar 

  20. North RB, Lanning A, Hessels R, Cutchis PN (1997) Spinal cord stimulation with percutaneous and plate electrodes: side effects and quantitative comparisons. Neurosurg Focus 2:e3

    Article  CAS  PubMed  Google Scholar 

  21. Melzack R, Wall PD (1965) Pain mechanisms: a new theory. Science 150:971–979

    Article  CAS  PubMed  Google Scholar 

  22. Foreman R, Linderoth B (2012) Neural mechanisms of spinal cord stimulation. Int Rev Neurobiol 107:87–113

    Article  PubMed  Google Scholar 

  23. Stiller CO, Cui JG, O’Connor WT, Brodin E, Meyerson BA, Linderoth B (1996) Release of gamma-aminobutyric acid in the dorsal horn and suppression of tactile allodynia by spinal cord stimulation in mononeuropathic rats. Neurosurgery 39:367–374; discussion 374–375

    Article  CAS  PubMed  Google Scholar 

  24. Cui JG, Meyerson BA, Sollevi A, Linderoth B (1998) Effect of spinal cord stimulation on tactile hypersensitivity in mononeuropathic rats is potentiated by simultaneous GABA(B) and adenosine receptor activation. Neurosci Lett 247:183–186

    Article  CAS  PubMed  Google Scholar 

  25. Guan Y (2012) Spinal cord stimulation: neurophysiological and neurochemical mechanisms of action. Curr Pain Headache Rep 16:217–225

    Article  PubMed  Google Scholar 

  26. Van Buyten JP, Al-Kaisy A, Smet I, Palmisani S, Smith T (2013) High-frequency spinal cord stimulation for the treatment of chronic back pain patients: results of a prospective multicenter European clinical study. Neuromodulation J Int Neuromodulation Soc 16:59–65; discussion 65–56

    Article  Google Scholar 

  27. Linderoth B, Meyerson B (2002) Spinal cord stimulation: mechanisms of action. In: Burchiel K (ed) Surgical management of pain. Thieme, New York, pp 505–526

    Google Scholar 

  28. Meyerson B, Linderoth B (2003) Spinal cord stimulation: mechanisms of action in neuropathic and ischemic pain. In: Simpson BA (ed) Electrical stimulation and the relief of pain. Elsevier Publishers, New York, pp 161–182 (chapter 111)

    Google Scholar 

  29. Linderoth B (2009) Spinal cord stimulation: a brief update on mechanisms of action. Eur J Pain 13:89–93

    Article  Google Scholar 

  30. Al-Kaisy A, Van Buyten JP, Smet I, Palmisani S, Pang D, Smith T (2014) Sustained effectiveness of 10 kHz high-frequency spinal cord stimulation for patients with chronic, low back pain: 24-month results of a prospective multicenter study. Pain Med 15:347–354

    Article  PubMed  Google Scholar 

  31. Kapural L, Yu C, Doust MW, et al (2015) Novel 10-kHz High-frequency Therapy (HF10 Therapy) Is Superior to Traditional Low-frequency Spinal Cord Stimulation for the Treatment of Chronic Back and Leg Pain: The SENZA-RCT Randomized Controlled Trial. Anesthesiology 123:851–860

    Google Scholar 

  32. De Ridder D, Vanneste S, Plazier M, van der Loo E, Menovsky T (2010) Burst spinal cord stimulation: toward paresthesia-free pain suppression. Neurosurgery 66:986–990

    Article  PubMed  Google Scholar 

  33. de Vos CC, Bom MJ, Vanneste S, Lenders MW, de Ridder D (2014) Burst spinal cord stimulation evaluated in patients with failed back surgery syndrome and painful diabetic neuropathy. Neuromodulation J Int Neuromodulation Soc 17:152–159

    Article  Google Scholar 

  34. Schu S, Slotty PJ, Bara G, von Knop M, Edgar D, Vesper J (2014) A prospective, randomised, double-blind, placebo-controlled study to examine the effectiveness of burst spinal cord stimulation patterns for the treatment of failed back surgery syndrome. Neuromodulation J Int Neuromodulation Soc 17:443–450

    Article  Google Scholar 

  35. Lind G, Meyerson BA, Winter J, Linderoth B (2003) Implantation of laminotomy electrodes for spinal cord stimulation in spinal anesthesia with intraoperative dorsal column activation. Neurosurgery 53:1150–1153; discussion 1153–1154

    Article  PubMed  Google Scholar 

  36. Kumar K, Lind G, Winter J, Gupta S, Bishop S, Linderoth B (2009) Spinal cord stimulation: placement of surgical leads via laminotomy – techniques and benefits. In: Krames E, Peckham PH, Rezai A (eds) Neuromodulation: journal of the international neuromodulation society. Academic/Elsevier, London

    Google Scholar 

  37. Papageorgiou AC, Croft PR, Ferry S, Jayson MI, Silman AJ (1995) Estimating the prevalence of low back pain in the general population. Evidence from the south manchester back pain survey. Spine (Phila Pa 1976) 20:1889–1894

    Article  CAS  Google Scholar 

  38. Turner JA, Loeser JD, Bell KG (1995) Spinal cord stimulation for chronic low back pain: a systematic literature synthesis. Neurosurgery 37:1088–1095; discussion 1095–1086

    Article  CAS  PubMed  Google Scholar 

  39. Mironer Y, Satterthwaite J, Lewis E, Haasis J, la Tourette P, Skoloff E, Diaz R (2008) Efficacy of a single, percutaneous, across midline, octrode lead using a “midline anchoring” technique in the treatment of chronic Low back and/or lower extremity pain: a retrospective study. Neuromodulation J Int Neuromodulation Soc 11:286–294

    Article  Google Scholar 

  40. North RB, Kidd DH, Lee MS, Piantodosi S (1994) A prospective, randomized study of spinal cord stimulation versus reoperation for failed back surgery syndrome: initial results. Stereotact Funct Neurosurg 62:267–272

    Article  CAS  PubMed  Google Scholar 

  41. Gybels J, Erdine S, Maeyaert J, Meyerson B, Winkelmuller W, Augustinsson L, Bonezzi C, Brasseur L, DeJongste M, Kupers R, Marchettini P, Muller-Schwefe G, Nitescu P, Plaghki L, Reig E, Spincemaille G, Thomson S, Tronnier V, Van Buyten JP (1998) Neuromodulation of pain. A consensus statement prepared in Brussels 16–18 January 1998 by the following task force of the European Federation of IASP Chapters (EFIC). Eur J Pain 2:203–209

    Article  CAS  PubMed  Google Scholar 

  42. Meyerson BA, Linderoth B (2000) Mechanisms of spinal cord stimulation in neuropathic pain. Neurol Res 22:285–292

    CAS  PubMed  Google Scholar 

  43. North RB (1991) Spinal cord stimulation for chronic, intractable pain: superiority of “multichannel” devices. Pain 44:119–130

    Article  CAS  PubMed  Google Scholar 

  44. Van Buyten JP, Van Zundert J, Vueghs P, Vanduffel L (2001) Efficacy of spinal cord stimulation: 10 years of experience in a pain centre in Belgium. Eur J Pain 5:299–307

    Article  PubMed  Google Scholar 

  45. Van de Kelft E, De La Porte C (1994) Spinal cord stimulation in failed back surgery syndrome. Qual Life Res 3:21–27

    Article  PubMed  Google Scholar 

  46. Taylor RS, Van Buyten JP, Buchser E (2005) Spinal cord stimulation for chronic back and leg pain and failed back surgery syndrome: a systematic review and analysis of prognostic factors. Spine 30:152–160

    Google Scholar 

  47. Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O’Callaghan J, Eisenberg E, Milbouw G, Buchser E, Fortini G, Richardson J, North RB (2007) Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndrome. Pain 132:179–188

    Article  PubMed  Google Scholar 

  48. Barolat G, Oakly J, Law J (2001) Spinal cord stimulation with a multiple electrode paddle lead is effective in treating intractable low back pain. Neuromodulation J Int Neuromodulation Soc 4:59–66

    Article  CAS  Google Scholar 

  49. Kapural L, Yu C, Doust MW, Gliner BE, Vallejo R, Sitzman BT, Amirdelfan K, Morgan DM, Brown LL, Yearwood TL, Bundschu R, Burton A, Yang T, Benyamin R, Burgher AH (2015) 188 randomized controlled clinical trial evaluating the safety and effectiveness of 10 kHz high-frequency and traditional low-frequency stimulation for the treatment of chronic back and leg pain: 18-month results. Neurosurgery 62(Suppl 1):228–229 (Clinical Neurosurgery)

    Article  Google Scholar 

  50. Bell GK, Kidd D, North RB (1997) Cost-effectiveness analysis of spinal cord stimulation in treatment of failed back surgery syndrome. J Pain Symptom Manag 13:286–295

    Article  CAS  Google Scholar 

  51. North RB, Kidd D, Shipley J, Taylor RS (2007) Spinal cord stimulation versus reoperation for failed back surgery syndrome: a cost effectiveness and cost utility analysis based on a randomized, controlled trial. Neurosurgery 61:361–368; discussion 368–369

    Article  PubMed  Google Scholar 

  52. Manca A, Kumar K, Taylor RS, Jacques L, Eldabe S, Meglio M, Molet J, Thomson S, O’Callaghan J, Eisenberg E, Milbouw G, Buchser E, Fortini G, Richardson J, Taylor RJ, Goeree R, Sculpher MJ (2008) Quality of life, resource consumption and costs of spinal cord stimulation versus conventional medical management in neuropathic pain patients with failed back surgery syndrome (PROCESS trial). Eur J Pain 12:1047–1058

    Article  PubMed  Google Scholar 

  53. Kemler MA, Furnee CA (2002) Economic evaluation of spinal cord stimulation for chronic reflex sympathetic dystrophy. Neurology 59:1203–1209

    Article  PubMed  Google Scholar 

  54. Taylor RS, Ryan J, O’Donnell R, Eldabe S, Kumar K, North RB (2010) The cost-effectiveness of spinal cord stimulation in the treatment of failed back surgery syndrome. Clin J Pain 26:463–469

    Article  PubMed  Google Scholar 

  55. Annemans L, Van Buyten J-P, Smith T, Al Kaisy A (2014) Cost Effectiveness of a novel 10 KHz High- Frequency Spinal Cord Stmulation System in Patients with Failed Back Surgery Syndrome (FBSS). J Long Term Eff Med Implants 24(2–3):173–183

    Google Scholar 

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Correspondence to Jean Pierre Van Buyten MD .

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Van Buyten, J.P. (2016). Neurostimulation for the Management of Failed Back Surgery Syndrome (FBSS). In: van de Kelft, E. (eds) Surgery of the Spine and Spinal Cord. Springer, Cham. https://doi.org/10.1007/978-3-319-27613-7_37

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  • DOI: https://doi.org/10.1007/978-3-319-27613-7_37

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