Abstract
For children with many conditions, splenectomy can cure the disease or effectively control the associated clinical symptoms. However, the risks associated with splenectomy such as overwhelming postsplenectomy sepsis are not trivial, and there is increasing recognition of other risks of splenectomy, such as thrombosis or vascular derangements. For select conditions, a partial splenectomy may effectively remove enough spleen to gain the desired clinical outcome while minimizing these risks. These are technically demanding operations that are nevertheless usually effective and well-tolerated.
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Bader-Meunier B, Gauthier F, Archambaud F, et al. Long-term evaluation of the beneficial effect of subtotal splenectomy for management of hereditary spherocytosis. Blood. 2001;97:399–403.
Bolton-Maggs PH, Langer JC, Iolascon A, et al. Guidelines for the diagnosis and management of hereditary spherocytosis – 2011 update. Br J Haematol. 2011;156:37–49.
Buesing KL, Tracy ET, Kiernan C, et al. Partial splenectomy for hereditary spherocytosis: a multi-institutional review. J Pediatr Surg. 2011;46:178–83.
Crary SE, Buchanan GR. Vascular complications after splenectomy for hematologic disorders. Blood. 2009;114:2861–8.
Davies JM, Lewis MPN, Wimperis J, et al. Review of guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen. Br J Haematol. 2011;155:308–17.
Gallagher PG. Red cell membrane disorders. Hematology Am Soc Hematol Educ Program. 2005;13:13–8.
Holdsworth R, Irving A, Cushieri A. Postsplenectomy sepsis and its mortality rate: actual versus perceived risks. Br J Surg. 1991;78:1031–8.
Price VE, Blanchette VS, Ford-Jones EL. The prevention and management of infections in children with asplenia or hyposplenia. Infect Dis Clin North Am. 2007;21:697–710.
Rice HE, Crary SE, Langer JC, et al. Comparative effectiveness of different types of splenectomy for children with congenital hemolytic anemias. J Pediatr. 2012;60:684–9.
Rice HE, Englum BR, Rothman J, et al. Clinical outcomes of splenectomy in children: report of the splenectomy in congenital hemolytic anemia (SICHA) registry. Am J Hematol. 2015;90:187–92.
Rodeghiero F, Stasi R, Gernsheimer T, et al. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura (ITP) of adults and children: report from an international working group. Blood. 2009;113:2386–93.
Thomsen RW, Schoonen WM, Farkas DK, et al. Risk for hospital contact with infection in patients with splenectomy: a population-based cohort study. Ann Intern Med. 2009;151:546–55.
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Tracy, E.T., Rice, H.E. (2017). Surgical Disorders of the Spleen. In: Mattei, P., Nichol, P., Rollins, II, M., Muratore, C. (eds) Fundamentals of Pediatric Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-27443-0_86
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DOI: https://doi.org/10.1007/978-3-319-27443-0_86
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