Abstract
Hodgkin lymphoma (HL) is the sixth most common type of cancer during childhood, accounting for approximately 5 % of all malignancies and half of all childhood lymphomas. HL is very rare in children under 5 years of age, whereas the incidence among patients younger than 15 years is 5.5 cases per million and for those aged 15–20 years reaches 12.1 cases per million [1–3]. A characteristic bimodal curve with an early peak during adolescence and a second peak in patients aged above 50 years old is well recognized.
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References
Gurney J, Bondy M (2006) Chapter 1. Epidemiology of childhood cancer. In: Pizzo AP, Poplack DG (eds) Principles and practice of pediatric oncology, 5th edn. Lippincott-Raven, Philadelphia, pp 1–13
Pourtsidis A, Doganis D, Baka M et al (2013) Differences between younger and older patients with childhood Hodgkin lymphoma. Pediatr Hematol Oncol 30:532–536
Pourtsidis A, Doganis D, Baka M et al (2012) Successful treatment in children with Hodgkin lymphoma in Greece; a 20-year experience in a single institution. Lymphoma 2012:Article ID 215868. doi:10.1155/2012/215868
Dinand V, Arya LS (2006) Epidemiology of childhood Hodgkin’s disease: is it different in developing countries? Indian Pediatr 43:141–147
Feldman A, Pittaluga S, Jaffe E (2006) Classification and histopathology of the lymphomas. In: Canellos G, Lister T, Young B (eds) The lymphomas, 2nd edn. Saunders Elsevier, Philadelphia, pp 2–25
Nievelstein R, Quarles van Ufford H, Kwee T et al (2012) Radiation exposure and mortality risk from CT and PET imaging of patients with malignant lymphoma. Eur Radiol 22:1946–1954
Furth C, Steffen IG, Amthauer H, Ruf J, Misch D, Schönberger S et al (2009) Early and late therapy response assessment with [18F]fluorodeoxyglucose positron emission tomography in pediatric Hodgkin’s lymphoma: analysis of a prospective multicenter trial. J Clin Oncol 27:4385–4391
Hudson M, Onciu M, Donaldson S (2006) Hodgkin’s disease. In: Pizzo P, Poplack D (eds) Principles and practise of pediatric oncology, 5th edn. Lippincott-Raven, Philadelphia, pp 695–721
Donaldson S, Link M, Weinstein H et al (2007) Final results of a prospective clinical trial with VAMP and low-dose involved-field radiation for children with low-risk Hodgkin’s disease. J Clin Oncol 25:332–337
Oguz A, Karadeniz C, Okur F et al (2005) Prognostic factors and treatment outcome in childhood Hodgkin disease. Pediatr Blood Cancer 45:670–675
Hudson M, Krasin M, Link M et al (2004) Risk-adapted, combined-modality therapy with VAMP/COP and response based, involved-field radiation for unfavorable pediatric Hodgkin’s disease. J Clin Oncol 22:4541–4550
Brusamolino E, Carella A (2007) Treatment of refractory and relapsed Hodgkin’s lymphoma: facts and perspectives. Haematologica 92:6–10
Bartlett N (2008) Modern treatment of Hodgkin lymphoma. Curr Opin Hematol 15:408–414
Hudson M, Donaldson S (1997) Chapter 21. Hodgkin’s disease. In: Pizzo P, Poplack D (eds) Principles and practice of pediatric oncology, 3rd edn. Lippincott-Raven Publishers, Philadelphia, pp 523–543
Kluge R, Körholz D (2011) Role of FDG-PET in staging and therapy of children with Hodgkin lymphoma. Klin Padiatr 223:315–319
Carbone PP, Kaplan HS, Musshoff K, Smithers DW, Tubiana M (1971) Report of the committee on Hodgkin’s disease staging classification. Cancer Res 31(11):1860
Lister TA, Crowther D, Sutcliffe SB, Glatstein E, Canellos GP, Young RC, Rosenberg SA, Coltman CA, Tubiana M (1989) Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin’s disease: Cotswolds meeting. J Clin Oncol 7(11):1630
Seth R, Puri K, Singh P, Selvam P, Kumar R (2012) The role of fluorodeoxyglucose positron emission tomography-computerized tomography in resolving therapeutic dilemmas in pediatric Hodgkin lymphoma. Indian J Nucl Med 27:141–144
Cheson BD, Pfistner B, Juweid ME, Gascoyne RD, Specht L, Horning SJ et al (2007) Revised response criteria for malignant lymphoma. J Clin Oncol 25:579–586
Rathore N, Eissa HM, Margolin JF et al (2012) Pediatric Hodgkin lymphoma: are we over-scanning our patients? Pediatr Hematol Oncol 29:415–423
Biasotti S, Garaventa A, Padovani P et al (2005) Role of active follow-up for early diagnosis of relapse after elective end of therapies. Pediatr Blood Cancer 45:781–786
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Doganis, D., Papaioannou, G.C., Prassopoulos, V.K. (2016). Hodgkin Lymphoma in Children. In: Andreou, J., Kosmidis, P., Gouliamos, A. (eds) PET/CT in Lymphomas. Springer, Cham. https://doi.org/10.1007/978-3-319-27380-8_18
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DOI: https://doi.org/10.1007/978-3-319-27380-8_18
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