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Enantioselective Gas Chromatography with Cyclodextrin in Odorant Analysis

  • Chapter
Springer Handbook of Odor

Part of the book series: Springer Handbooks ((SHB))

Abstract

This chapter concerns enantioselective gas-chromatography (GlossaryTerm

Es-GC

) with cyclodextrin derivatives as chiral stationary phases for chiral recognition of volatile odorants in the flavor and fragrance field. The text is divided into two main parts. The first one is more general and deals with enantiomers and odor and need for chiral recognition, evolution of chiral stationary phases for Es-GC since its beginning, followed by the history of cyclodextrins and their applications to enantioselective GlossaryTerm

GC

. It also includes some theoretical aspects of enantiomer separation with cyclodextrin derivatives and their influence on routine chiral recognition.

The second part concerns the strategy of chiral recognition in routine analysis with cyclodextrin derivatives as chiral stationary phases illustrated by examples with real natural product samples. This part describes enantiomer automatic identification or their excess or ratio determination in complex mixtures by enantioselective GC combined with mass spectrometry; in particular it deals with the potential of multidimensional techniques and of fast GC in chiral recognition and the role played by mass spectrometry. The last paragraph concerns the use of total analysis systems in chiral recognition.

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Abbreviations

CD:

cyclodextrin

ee:

enantiomeric excess

er:

enantiomeric ratio

Es-GC:

enantioselective gas chromatography

FID:

flame ionization detection

GC:

gas chromatography

HCC-HS:

high concentration capacity headspace

HPLC:

high performance liquid chromatography

HS-LPME:

headspace liquid-phase microextraction

HS-SPME:

headspace solid-phase microextraction

HS-STE:

headspace sorptive tape extraction

HS:

headspace

HSSE:

headspace sorptive extraction

IRMS:

isotope ratio mass spectrometry

IT:

ion trap

MS:

mass spectrometry

PDMS:

polydimethylsiloxane

RIA:

retention index allowance

RTL:

retention time locking

S-HS:

static headspace

TOF:

time-of-flight

UV–Vis:

ultraviolet-visible

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Authors and Affiliations

  1. Dept. of Drug Science and Technology, University of Torino, Via Pietro Giuria 9, 10125, Torino, Italy

    Cecilia Cagliero, Barbara Sgorbini, Chiara Cordero, Erica Liberto, Patrizia Rubiolo & Carlo Bicchi

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  1. Cecilia Cagliero
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  2. Barbara Sgorbini
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  3. Chiara Cordero
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  4. Erica Liberto
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  5. Patrizia Rubiolo
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  6. Carlo Bicchi
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Correspondence to Cecilia Cagliero .

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  1. Fraunhofer-Institut for Process Engineering and Packaging, Giggenhauser Str. 35, 85354, Freising, Germany

    Andrea Buettner

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Cagliero, C., Sgorbini, B., Cordero, C., Liberto, E., Rubiolo, P., Bicchi, C. (2017). Enantioselective Gas Chromatography with Cyclodextrin in Odorant Analysis. In: Buettner, A. (eds) Springer Handbook of Odor. Springer Handbooks. Springer, Cham. https://doi.org/10.1007/978-3-319-26932-0_19

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