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HIV-Associated Hodgkin Lymphoma

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Book cover HIV-associated Hematological Malignancies

Abstract

Hodgkin lymphoma (HL) is one of the most common non-AIDS-defining malignancies in patients infected with HIV. Unfavorable features such as higher frequency of advanced-stage disease and extranodal involvement are frequently encountered. Prior to the advent of combined antiretroviral therapy (cART), the prognosis of patients with HIV-HL was poor. However, with standard curative-intent therapy and modern cART, the outcome is similar to that reported in the general population. In patients with early favorable HL two cycles of ABVD followed by involved-field radiation (IF-RT) is considered standard of care. Patients with early unfavorable HL should receive four cycles of ABVD + IF-RT while six cycles of ABVD or six cycles of BEACOPP baseline should be given to patients with advanced HIV-HL.

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Authors and Affiliations

  1. Department of Hematology and Oncology, Red Cross Hospital, University of Munich, Munich, Germany

    Marcus Hentrich MD

  2. Division of Medical Oncology A, National Cancer Institute, Aviano, Italy

    Michele Spina

  3. Centre for Haemato-Oncology, St Bartholomew’s Hospital, Barts Cancer Institute, Queen Mary University of London, London, UK

    Silvia Montoto MD

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  1. Marcus Hentrich MD
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  2. Michele Spina
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Correspondence to Marcus Hentrich MD .

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Editors and Affiliations

  1. Department of Hematology and Oncology, Red Cross Hospital, Uni of Munich, Munich, Germany

    Marcus Hentrich

  2. Dept. of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA

    Stefan K. Barta

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Hentrich, M., Spina, M., Montoto, S. (2016). HIV-Associated Hodgkin Lymphoma. In: Hentrich, M., Barta, S. (eds) HIV-associated Hematological Malignancies. Springer, Cham. https://doi.org/10.1007/978-3-319-26857-6_9

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