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Chemotherapy and Interactions with Combination Antiretroviral Therapy

  • Nicolas MounierEmail author
  • Michelle A. Rudek
Chapter

Abstract

Combination antiretroviral therapy (cART) has markedly reduced morbidity and mortality of AIDS-related complications in patients with HIV. Despite the overall success of cART, hematological malignancies remain a common source of morbidity and mortality. In this chapter, we discuss the management of cART in relation to antineoplastic agents and potential pharmacological interactions between cART and antineoplastic agents and consider how to combine cART and antineoplastic agents in patients with HIV.

Keywords

Vinca Alkaloid Drug Interaction Potential CYP450 Isozyme cART Regimen Unconjugated Hyperbilirubinemia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of Onco-HematologyArchet HospitalNiceFrance
  2. 2.The Sidney Kimmel Comprehensive Cancer CenterJohns Hopkins UniversityBaltimoreUSA

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