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Macular Dystrophies: Management and Interventions

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Macular Dystrophies

Abstract

Inherited macular dystrophies comprise a highly heterogeneous group of diseases characterized by irreversible loss of central vision as a result of atrophy of the macula and underlying retinal pigment epithelium. Despite significant progress in understanding molecular bases of these diseases, there are still no preventive or curative treatments. This chapter discusses vision restoration strategies and focuses on innovative therapies for inherited macular diseases that are currently under development and evaluation, e.g., gene therapy, retinal prosthesis, and optogenetics.

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Authors and Affiliations

  1. Institut de la Vision, Sorbonne Universités, UPMC University Paris 06, UMR_S 968, INSERM U968, CNRS UMR_7210, 17 rue Moreau, Paris, 75012, France

    Katia Marazova PhD & José-Alain Sahel MD

  2. Centre Hospitalier National d’Ophtalmologie des Quinze-Vingts, DHU Sight Again, INSERM-DHOS CIC 1423, Paris, France

    José-Alain Sahel MD

Authors
  1. Katia Marazova PhD
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  2. José-Alain Sahel MD
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Correspondence to José-Alain Sahel MD .

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Editors and Affiliations

  1. University Paris Est Créteil, Créteil, France

    Giuseppe Querques

  2. Ophthalmology, University Paris Est Créteil, Créteil, France

    Eric H. Souied

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Marazova, K., Sahel, JA. (2016). Macular Dystrophies: Management and Interventions. In: Querques, G., Souied, E. (eds) Macular Dystrophies. Springer, Cham. https://doi.org/10.1007/978-3-319-26621-3_11

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  • DOI: https://doi.org/10.1007/978-3-319-26621-3_11

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