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Pathophysiology of Lesions in Coronary Bypass

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Coronary Graft Failure

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Abstract

Considering the importance of myocardial revascularization surgery in the context of the twenty-first century, there has been a need to explore the pathophysiology of injuries that affect graft bridges. A qualitative analysis of these factors that directly or indirectly influence the failure of grafts in the postoperative period of coronary artery bypass grafting (CABG) is an approach that this chapter aims to address in an enlightening way. Among the predictive factors are ethnicity, advanced age, smoking, dyslipidemias, systemic arterial hypertension, diabetes mellitus (DM), renal insufficiency, and previous myocardial infarction. Considering the high incidence rates of postoperative complications of myocardial revascularization surgery (MRS), we aim to analyze the reasons for the low patency of certain grafts compared with others, and to determine the possible factors responsible for the appearance of lesions in bypass grafts. Therefore, on the basis of a broad literature review concerning those issues, we aim to clarify the pathophysiology of lesions affecting coronary bypass grafts.

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Authors and Affiliations

  1. Unilago School of Medicine, Sao Jose Rio Preto, São Paulo, Brazil

    Edmo Atique Gabriel PhD

  2. Unilago School of Medicine, União das faculdades dos Grandes Lagos, Mirassol, São Paulo, Brazil

    Letícia Oliveira MD

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  1. Edmo Atique Gabriel PhD
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Correspondence to Edmo Atique Gabriel PhD .

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Editors and Affiliations

  1. Cardiology, Army's Center for Cardiovascular Di, Bucharest, Romania

    Ion C. Ţintoiu

  2. Department of Surgery, Chinese University of Hong Kong, Sha Tin, Hong Kong

    Malcolm John Underwood

  3. University Fribourg, Hospital HFR Fribourg, Fribourg, Fribourg, Switzerland

    Stephane Pierre Cook

  4. Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan

    Hironori Kitabata

  5. University Medical Center, Texas Tech Univ. Health Science Center, EL PASO, Texas, USA

    Aamer Abbas

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Gabriel, E.A., Oliveira, L. (2016). Pathophysiology of Lesions in Coronary Bypass. In: Ţintoiu, I., Underwood, M., Cook, S., Kitabata, H., Abbas, A. (eds) Coronary Graft Failure. Springer, Cham. https://doi.org/10.1007/978-3-319-26515-5_27

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