Skip to main content

Multivessel Disease, Risk of Graft Failure

  • Chapter
  • First Online:
  • 1016 Accesses

Abstract

Multivessel disease (MVD) is a challange for both interventional cardiologists and cardiovascular surgeons. Despite all the remarkable progress of modern medicine, this condition frequently requires surgical myocardial revascularization in the drug-eluting stent era. Coronary artery bypass grafting is known to improve survival. However, in patients with MVD, the fate of the graft is negatively influenced by a cumulation of risk factors. The use of multiple conduits with specific long-term patencies, the technical aspects regarding the complexity of the procedure including personal technical skills but also institutional facilities and associated comorbidities that promote accelerated atherosclerosis lead to an increased risk of graft failure in patients with MVD.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Hueb W, Lopes N, Gersh B, et al. Ten-year follow-up survival of the Medicine, Angioplasty or Surgery Study (MASS II). A randomized controlled clinical trial of 3 therapeutic strategies for multivessel coronary artery disease. Circulation. 2010;122:949–57.

    Article  PubMed  Google Scholar 

  2. Sipahi I, Akay MH, Dagdelen S, et al. Coronary artery bypass grafting vs percutaneous coronary intervention and long-term mortality and morbidity in multivessel disease: meta-analysis of randomized clinical trials of the arterial grafting and stenting era. JAMA Intern Med. 2014;174(2):223–30.

    Article  PubMed  Google Scholar 

  3. Garcia S, Sandoval Y, Roukoz H, et al. Outcomes after complete versus incomplete revascularization of patients with multivessel coronary artery disease: a meta-analysis of 89,883 patients enrolled in randomized clinical trials and observational studies. JACC. 2013;62(16):1421–31.

    Article  PubMed  Google Scholar 

  4. Tonino PA, De Bruyne B, Pijls NH, et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med. 2009;360:213–24.

    Article  CAS  PubMed  Google Scholar 

  5. De Bruyne B. Multivessel disease from reasonably incomplete to functionally complete revascularization. Circulation. 2012;125:2557–9.

    Article  PubMed  Google Scholar 

  6. Windecker S, Kolh P, Alfonso F, et al. 2014 ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J. 2014;35:2541–619.

    Article  PubMed  Google Scholar 

  7. Tatoulis J, Buxton B, Fuller J. Patencies of 2,127 arterial to coronary conduits over 15 years. Ann Thorac Surg. 2004;77:93–101.

    Article  PubMed  Google Scholar 

  8. Taggart DP. Current status of arterial grafts for coronary artery bypass grafting. Am Cardiothorac Surg. 2013;2(4):427–30.

    Google Scholar 

  9. Locker C, Schaff H, Dearani J, et al. Multiple arterial grafts improve late survival of patients undergoing coronary artery bypass graft surgery. Analysis of 8,622 patients with multivessel disease. Circulation. 2012;126:1023–30.

    Article  PubMed  Google Scholar 

  10. Lytle BW, Blackstone EH, Sabik JF, et al. The effect of bilateral internal thoracic artery grafting on survival during 20 postoperative years. Ann Thorac Surg. 2004;78:2005–12.

    Article  PubMed  Google Scholar 

  11. Galbut DL, Kurlansky PA, Traad EA, et al. Bilateral internal thoracic artery grafting improves long-term survival in patients with reduced ejection fraction: a propensity-matched study with 30-year follow-up. J Thorac Cardiovasc Surg. 2012;143:844–53.

    Article  PubMed  Google Scholar 

  12. Benedetto U, Angeloni E, Refice S, et al. Radial artery versus saphenous vein graft patency: meta-analysis of randomized controlled trials. J Thorac Cardiovasc Surg. 2010;139:229–31.

    Article  PubMed  Google Scholar 

  13. Athanasiou T, Saso S, Rao C, et al. Radial artery versus saphenous vein conduits for coronary artery bypass surgery: forty years of competition-which conduit offers better patency? A systematic review and meta-analysis. Eur J Cardiothorac Surg. 2011;40:208–20.

    Article  PubMed  Google Scholar 

  14. Hu X, Zhao Q. Systematic comparison of the effectiveness of radial artery and saphenous vein or right internal thoracic artery coronary bypass grafts in non-left anterior descending coronary arteries. J Zhejiang Univ Sci B. 2011;12:273–9.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Cao C, Manganas C, Horton M, et al. Angiographic outcomes of radial artery versus saphenous vein in coronary artery bypass graft surgery: a meta-analysis of randomized controlled trials. J Thorac Cardiovasc Surg. 2013;146:255–61.

    Article  PubMed  Google Scholar 

  16. Benedetto U, Raja SG, Albanese A, et al. Searching for the second best graft for coronary artery bypass surgery: a network meta-analysis of randomized controlled trials. Eur J Cardiothorac Surg. 2015;47:59–65.

    Google Scholar 

  17. Rankin JS, Tuttle RH, Wechsler AS, et al. Techniques and benefits of multiple internal mammary artery bypass at 20 years of follow-up. Ann Thorac Surg. 2007;83:1008–14.

    Article  PubMed  Google Scholar 

  18. Kurlansky PA, Traad EA, Dorman MJ, et al. Thirty-year follow-up defines survival benefit for second internal mammary artery in propensity-matched groups. Ann Thorac Surg. 2010;90:101–8.

    Article  PubMed  Google Scholar 

  19. Tatoulis J, Buxton BF, Fuller JA. The right internal thoracic artery: the forgotten conduit-5,766 patients and 991 angiograms. Ann Thorac Surg. 2011;92:9–15.

    Article  PubMed  Google Scholar 

  20. Taggart DP, Altman DG, Gray AM, et al. Randomized trial to compare bilateral vs. single internal mammary coronary artery bypass grafting: 1-year results of the Arterial Revascularization Trial (ART). Eur Heart J. 2010;31:2470–81.

    Article  PubMed  Google Scholar 

  21. Al-Sabti HA, Al Kindi A, Al Rasadi K, et al. Saphenous vein graft vs. radial artery graft searching for the best second coronary artery bypass graft. J Saudi Heart Assoc. 2013;25(4):247–54.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Fitzgibbon GM, Kafka HP, Leach AJ, et al. Coronary bypass graft fate and patient outcome: angiographic follow-up of 5,065 grafts related to survival and reoperation in 1,388 patients during 25 years. J Am Coll Cardiol. 1996;28:616–26.

    Article  CAS  PubMed  Google Scholar 

  23. Buxton BF, Ruengsakulrach P, Fuller J, et al. The right internal thoracic artery graft-benefits of grafting the left coronary system and native vessels with a high grade stenosis. Eur J Cardiothorac Surg. 2000;18:255–61.

    Article  CAS  PubMed  Google Scholar 

  24. De Paulis R, de Notaris S, Scaffa R, et al. The effect of bilateral internal thoracic artery harvesting on superficial and deep sternal infection: The role of skeletonization. J Thorac Cardiovasc Surg. 2005;129:536–43.

    Article  PubMed  Google Scholar 

  25. Maniar HS, Sundt TM, Barner HB, et al. Effect of target stenosis and location on radial artery graft patency. J Thorac Cardiovasc Surg. 2002;123:45–52.

    Article  PubMed  Google Scholar 

  26. Pijls NH, Fearon WF, Tonino PA, et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention in patients with multivessel coronary artery disease: 2 –year follow-up of the FAME (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) study. J Am Coll Cardiol. 2010;56(3):177–84.

    Article  PubMed  Google Scholar 

  27. Harskamp RE, Alexander JH, Schulte PJ, et al. Vein graft preservation solutions, patency, and outcomes after coronary artery bypass graft surgery: follow-up from the PREVENT IV randomized clinical trial. JAMA Surg. 2014;149(8):798–805.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Anghel L, Arsenescu Georgescu C. What is hiding the diabetes in the new left bundle branch block patients? Acta Endocrinol (Buc). 2014;10(3):425–34.

    Article  Google Scholar 

  29. Pleşoianu CE, Arsenescu Georgescu C. Heart-ridden diabetes mellitus. Rom J Art Creat. 2013;1(2):238–60.

    Google Scholar 

  30. Lima EG, Hueb W, Garcia RM, et al. Impact of diabetes on 10-year outcomes of patients with multivessel coronary artery disease in the Medicine, Angioplasty, or Surgery Study II (MASS II) trial. Am Heart J. 2013;166(2):250–7.

    Article  PubMed  Google Scholar 

  31. De Luca G, Schaffer A, Verdoia M, et al. Meta–analysis of 14 trials comparing bypass grafting vs. drug-eluting stents in diabetic patients with multivessel coronary artery disease. Nutr Metab Cardiovasc Dis. 2014;24(4):344–54.

    Article  PubMed  Google Scholar 

  32. Chikwe J, Castillo JG, Rahmanian PB, et al. The impact of moderate–to-end–stage renal failure on outcomes after coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth. 2010;24(4):574–9.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C˘at˘alina Arsenescu Georgescu MD, PhD, FESC .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Georgescu, C.A., Plesoianu, C.E. (2016). Multivessel Disease, Risk of Graft Failure. In: Ţintoiu, I., Underwood, M., Cook, S., Kitabata, H., Abbas, A. (eds) Coronary Graft Failure. Springer, Cham. https://doi.org/10.1007/978-3-319-26515-5_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-26515-5_14

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-26513-1

  • Online ISBN: 978-3-319-26515-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics