Abstract
While the chromosome number was still being debated, the structure and function of DNA is spectacularly revealed. Finding the structure of DNA was, of course, going to be a spectacular achievement, but in many ways, it was a more straightforward process of discovery than finding the chromosome number. The chemical formula was already well known, but the structure was not until Watson and Crick revealed it. Strangely, pivotal though this information was, the structure of DNA did little to progress our knowledge of chromosomes.
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References
Avery OT, MacLeod CM, McCarty M (1944) Studies on the chemical nature of the substance inducing transformation of pneumococcal types induction of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus type III. J Exp Med 79(2):137–158
Crick FHC (1966) Codon-anticodon pairing: the wobble hypothesis. J Mol Biol 19(2):548–555
Crick F, Barnett L, Brenner S, Watts-Tobin RJ (1961) General nature of the genetic code for proteins. Nature 192:1227–1232
Meselson M, Stahl FW (1958) The replication of DNA in Escherichia coli. Proc Natl Acad Sci 44(7):671–682
Nirenberg MW, Matthaei JH (1961) The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polyribonucleotides. Proc Natl Acad Sci 47(10):1588–1602
Popper K (1934) Reprint (1959) Logic of scientific discovery. Basic Books, New York
Popper KR (1982) Logik der Forschung, vol. 4. JCB Mohr (Paul Siebeck), Tübingen
Watson JD, Crick FH (1953a) Molecular structure of nucleic acids. Nature 171(4356):737–738
Watson JD, Crick FH (1953b) The structure of DNA. In: Cold spring harbor symposia on quantitative biology 18. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp 123–131
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Wall, W.J. (2016). The Implications of DNA Structure. In: The Search for Human Chromosomes. Springer, Cham. https://doi.org/10.1007/978-3-319-26336-6_6
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DOI: https://doi.org/10.1007/978-3-319-26336-6_6
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