Abstract
Water and solutes are transported through three different mechanisms: (1) ultrafiltration, (2) convection, and (3) diffusion. Ultrafiltration is the movement of fluid through a semipermeable membrane driven by a pressure gradient. This transport mechanism is used in slow continuous ultrafiltration (SCUF), continuous veno-venous hemofiltration (CVVH), continuous veno-venous dialysis (CVVHD), and continuous veno-venous hemodialfiltration (CVVHDF). Convection transport mechanism is the removal of solutes, especially middle and large molecules, along with a large volume of fluid simultaneously. Convection transport mechanism is used in CVVH and CVVHDF. Diffusion is the removal of small molecules by concentration gradient across a semipermeable membrane. This transport is used in CVVHD and CVVHDF.
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Assadi, F., Sharbaf, F.G. (2016). Water and Solute Movements: Basic Physiology. In: Pediatric Continuous Renal Replacement Therapy. Springer, Cham. https://doi.org/10.1007/978-3-319-26202-4_2
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DOI: https://doi.org/10.1007/978-3-319-26202-4_2
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