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Paget’s Disease of the Breast

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Breast Disease

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Abstract

Paget’s disease of the breast is a rare breast tumor that was first identified by Sir James Paget in 1874. It is characterized by eczema-form changes accompanied with erosion and ulceration of the nipple and areolar epidermis. It is mostly correlated with ductal carcinoma in situ (DCIS); additionally, it can be accompanied by invasive ductal carcinoma (IDC). The diagnosis is determined upon microscopically observing Paget cells in a skin biopsy. The width of the lesion is evaluated via mammography and MRI in patients for whom breast-preserving surgery is planned. Depending on the extent of the lesion, sentinel lymph node biopsy and axillary curettage for those having axillary metastases are the treatment alternatives to breast-preserving surgery or mastectomy.

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Author information

Authors and Affiliations

  1. Breast Unit, Department of General Surgery, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey

    Abdullah İğci MD, FACS

  2. Department of General Surgery, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey

    Nihat Aksakal MD & Enver Özkurt MD

Authors
  1. Abdullah İğci MD, FACS
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  2. Nihat Aksakal MD
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  3. Enver Özkurt MD
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Corresponding author

Correspondence to Abdullah İğci MD, FACS .

Editor information

Editors and Affiliations

  1. Inst of Oncology,Ist Tıp Fak, Istanbul University, Istanbul, Turkey

    Adnan Aydiner

  2. General Surgery, Istanbul Univ Istanbul Fac of Med, Istanbul, Turkey

    Abdullah İgci

  3. Breast Surgery,, Magee-Womens Hospital, Pittsburg, USA

    Atilla Soran

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© 2016 Springer International Publishing Switzerland

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İğci, A., Aksakal, N., Özkurt, E. (2016). Paget’s Disease of the Breast. In: Aydiner, A., İgci, A., Soran, A. (eds) Breast Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-26012-9_25

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  • DOI: https://doi.org/10.1007/978-3-319-26012-9_25

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-26010-5

  • Online ISBN: 978-3-319-26012-9

  • eBook Packages: MedicineMedicine (R0)

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