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Systemic Therapy for Locally Advanced Breast Cancer

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Breast Disease

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Abstract

Neoadjuvant therapy refers to the systemic treatment of breast cancer prior to definitive surgical therapy. Neoadjuvant therapy is administered with the objective of improving surgical outcomes in patients with breast cancer for whom a primary surgical approach is technically not feasible and for patients with operable breast cancer who desire breast conservation but for whom either a mastectomy is required or a partial mastectomy would result in a poor cosmetic outcome. In addition, neoadjuvant chemotherapy is appropriate for patients with HER2-positive or triple-negative breast cancer who are most likely to have a good locoregional response to treatment, regardless of the size of their breast cancer at presentation.

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Author information

Authors and Affiliations

  1. Department of Medical Oncology, Memorial Hospital, Istanbul, Turkey

    Serkan Keskin MD

  2. Department of Medical Oncology, Istanbul University Istanbul Medical Faculty, Institute of Oncology, Istanbul, Turkey

    Adnan Aydiner MD

Authors
  1. Serkan Keskin MD
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  2. Adnan Aydiner MD
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Correspondence to Adnan Aydiner MD .

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Editors and Affiliations

  1. Inst of Oncology,Ist Tıp Fak, Istanbul University, Istanbul, Turkey

    Adnan Aydiner

  2. General Surgery, Istanbul Univ Istanbul Fac of Med, Istanbul, Turkey

    Abdullah İgci

  3. Breast Surgery,, Magee-Womens Hospital, Pittsburg, USA

    Atilla Soran

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Keskin, S., Aydiner, A. (2016). Systemic Therapy for Locally Advanced Breast Cancer. In: Aydiner, A., İgci, A., Soran, A. (eds) Breast Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-26012-9_15

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  • DOI: https://doi.org/10.1007/978-3-319-26012-9_15

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