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Mucoadhesive Polymers and Ocular Lubricants

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Pharmacology of Ocular Therapeutics

Abstract

Dry Eye Disease (DED) is defined as a multifactorial condition that results in discomfort, visual disturbance, tear film instability and damage to the ocular surface. It is characterized by the increased osmolarity of the tear film and inflammation of the ocular surface. Tear film stability is maintained by the coordinated functions of the outer lipid monolayer with its critical composition and the contents of aqueous interface. This chapter discusses the structure and function attributing to tear film integrity, mucoadhesive polymers used in tear substitutes/lubricants, tear secretagogues agents, anti-inflammatory immunosuppressants, and use of autologous serum, umbilical cord serum for the management of dry eye.

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Authors and Affiliations

  1. Ocular Pharmacology and Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India

    Thirumurthy Velpandian BPharm, MS(Pharmacol), PhD & Laxmi Moksha M. Pharm

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  1. Thirumurthy Velpandian BPharm, MS(Pharmacol), PhD
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  2. Laxmi Moksha M. Pharm
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Correspondence to Thirumurthy Velpandian BPharm, MS(Pharmacol), PhD .

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Editors and Affiliations

  1. Ocular Pharmacology and Pharmacy, Dr. RP Centre for Ophthalmic Sciences, New Delhi, India

    Thirumurthy Velpandian

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Velpandian, T., Moksha, L. (2016). Mucoadhesive Polymers and Ocular Lubricants. In: Velpandian, T. (eds) Pharmacology of Ocular Therapeutics. Adis, Cham. https://doi.org/10.1007/978-3-319-25498-2_10

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