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Viral Transport and Interaction with the Host Cytoskeleton

  • Manfred HeinleinEmail author
Chapter

Abstract

Viruses depend on host cell functions for replication and for spreading their genomes between cells and throughout the organism. The spread of viruses in plants relies on the ability of virus-encoded movement proteins (MPs) and interacting host components to facilitate the transport of the infectious viral genomes through plasmodesmata (PD), the gatable cytoplasmic cell wall channels through which adjacent cells are connected. Studies in the last 20 years have provided insights into the role of membranes and the dynamic cytoskeleton in the cell-to-cell movement of viruses. Using tobacco mosaic virus (TMV) as an example, this article highlights the specific roles of the actin and microtubule cytoskeletons in supporting the endoplasmic reticulum (ER)-associated assembly and trafficking of viral protein:RNA complexes and their targeting to PD.

Keywords

Tobacco mosaic virus Viral replication complex Movement protein Plasmodesmata Microtubules Actin Myosin Endoplasmic reticulum 

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© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Department of Integrative VirologyIBMP-CNRSStrasbourgFrance
  2. 2.Botany, Department of Environmental SciencesUniversity of BaselBaselSwitzerland

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