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Sugar and Glycerol Transport in Saccharomyces cerevisiae

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Yeast Membrane Transport

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 892))

Abstract

In Saccharomyces cerevisiae the process of transport of sugar substrates into the cell comprises a complex network of transporters and interacting regulatory mechanisms. Members of the large family of hexose (HXT) transporters display uptake efficiencies consistent with their environmental expression and play physiological roles in addition to feeding the glycolytic pathway. Multiple glucose-inducing and glucose-independent mechanisms serve to regulate expression of the sugar transporters in yeast assuring that expression levels and transporter activity are coordinated with cellular metabolism and energy needs. The expression of sugar transport activity is modulated by other nutritional and environmental factors that may override glucose-generated signals. Transporter expression and activity is regulated transcriptionally, post-transcriptionally and post-translationally. Recent studies have expanded upon this suite of regulatory mechanisms to include transcriptional expression fine tuning mediated by antisense RNA and prion-based regulation of transcription. Much remains to be learned about cell biology from the continued analysis of this dynamic process of substrate acquisition.

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Authors and Affiliations

  1. Department of Viticulture and Enology, University of California, Davis, CA, 95616, USA

    Linda F. Bisson, Qingwen Fan & Gordon A. Walker

Authors
  1. Linda F. Bisson
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  2. Qingwen Fan
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  3. Gordon A. Walker
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Correspondence to Linda F. Bisson .

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Editors and Affiliations

  1. Dept. of Microbiology, University of Córdoba, Córdoba, Spain

    José Ramos

  2. Department of Membrane Transport, Institute of Physiology, The Czech Academy of Sciences, Prague, Czech Republic

    Hana Sychrová

  3. Department of Mathematics and Technology, University of Applied Sciences, Koblenz, Remagen, Germany

    Maik Kschischo

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Bisson, L.F., Fan, Q., Walker, G.A. (2016). Sugar and Glycerol Transport in Saccharomyces cerevisiae . In: Ramos, J., Sychrová, H., Kschischo, M. (eds) Yeast Membrane Transport. Advances in Experimental Medicine and Biology, vol 892. Springer, Cham. https://doi.org/10.1007/978-3-319-25304-6_6

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