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Multimodal Imaging in Glioma Surgery

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Intraoperative Ultrasound (IOUS) in Neurosurgery

Abstract

In this chapter, the authors present current possibilities of intraoperative visualization of brain gliomas. These tumors are often macroscopically similar to the normal brain but typically well visualized by magnetic resonance imaging (MRI). Therefore, neuronavigation based on preoperative MRI is often used in order to localize glioma tissue. However, the accuracy of neuronavigation is limited due to the brain shift, and after some tumor debulking, it becomes unreliable. Intraoperative imaging techniques – intraoperative MRI and intraoperative ultrasound – represent a solution to this problem as these modalities enable an update of the neuronavigation data during the surgical procedure. In malignant gliomas, utilization of fluorescent agents is another possibility of intraoperative tumor tissue visualization. Benefits and pitfalls of aforementioned methods are discussed, with special emphasis on intraoperative ultrasound.

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Authors and Affiliations

  1. Department of Neurosurgery, Comenius University Faculty of Medicine, University Hospital Bratislava, Limbova 5, Bratislava, Slovakia

    Andrej Šteňo MD, PhD

  2. Department of Neurosurgery, University of Milano-Bicocca, San Gerardo University Hospital, Monza, Italy

    Carlo Giussani & Matteo Riva

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  1. Andrej Šteňo MD, PhD
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  2. Carlo Giussani
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  3. Matteo Riva
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Correspondence to Andrej Šteňo MD, PhD .

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Editors and Affiliations

  1. Fondazione IRCCS Istituto Neurologico C. Besta, Milano, Italy

    Francesco Prada

  2. UO Radiologia Oncologica, Humanitas Univ. and Research Hospital UO Radiologia Oncologica, Busto Arsizio, Italy

    Luigi Solbiati

  3. UO Radiologia, Ospedale Valduce, Como, Como, Italy

    Alberto Martegani

  4. Istituto Neurologico C. Besta, Fondazione IRCCS, Milano, Italy

    Francesco DiMeco

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Šteňo, A., Giussani, C., Riva, M. (2016). Multimodal Imaging in Glioma Surgery. In: Prada, F., Solbiati, L., Martegani, A., DiMeco, F. (eds) Intraoperative Ultrasound (IOUS) in Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-25268-1_8

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