Skip to main content

Andrologic Sequelae in Prostatitis Patients

  • Chapter
  • First Online:
Prostatitis and Its Management

Abstract

Of the four categories of prostatitis, chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most prevalent. CP/CPPS is also the form of prostatitis that has been most associated with andrologic sequelae. These complications include decreased testosterone, erectile dysfunction, painful ejaculation, and premature ejaculation. The prevalence of these symptoms in patients with CP/CPPS is high and plays a significant role in the morbidity of patients. As such, a sexual function assessment is an important part of evaluating any patient with pelvic or perineal pain. Treatment strategies that have addressed sexual dysfunction include testosterone replacement therapy, alpha-adrenergic blockers, and PDE5s. This chapter will discuss the association of prostatitis with endocrine abnormalities and sexual dysfunction, with a focus on pathophysiology and treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Yunda IF, Imshinetskaya LP (1977) Testosterone excretion in chronic prostatitis. Andrologia 9:89–94

    Article  CAS  PubMed  Google Scholar 

  2. Pontari MA, Ruggieri MR (2004) Mechanisms in prostatitis/chronic pelvic pain syndrome. J Urol 172:839–845

    Article  PubMed Central  PubMed  Google Scholar 

  3. Jia Y, Liu X, Yan J et al (2015) The alteration of inflammatory markers and apoptosis on chronic prostatitis induced by estrogen and androgen. Int Urol Nephrol 47:39–46

    Article  CAS  PubMed  Google Scholar 

  4. Meng J, Mostaghel EA, Vakar-Lopez F et al (2011) Testosterone regulates tight junction proteins and influences prostatic autoimmune responses. Horm Cancer 2:145–156

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  5. Pang R, Lu J, Zhou X et al (2015) MP25-02 testosterone replacement therapy for hypogonadal patients with chronic prostatitis/chronic pelvic pain syndrome. J Urol 193, e285

    Article  Google Scholar 

  6. Tuncel A, Akbulut Z, Atan A et al (2006) Common symptoms in men with prostatic inflammation. Int Urol Nephrol 38:583–586

    Article  PubMed  Google Scholar 

  7. Liang C-Z, Zhang X-J, Hao Z-Y et al (2004) Prevalence of sexual dysfunction in Chinese men with chronic prostatitis. BJU Int 93:568–570

    Article  PubMed  Google Scholar 

  8. Gonen M, Kalkan M, Cenker A et al (2005) Prevalence of premature ejaculation in Turkish men with chronic pelvic pain syndrome. J Androl 26:601–603

    Article  PubMed  Google Scholar 

  9. Lee SWH, Liong ML, Yuen KH et al (2008) Adverse impact of sexual dysfunction in chronic prostatitis/chronic pelvic pain syndrome. Urology 71:79–84

    Article  PubMed  Google Scholar 

  10. Trinchieri A, Magri V, Cariani L et al (2007) Prevalence of sexual dysfunction in men with chronic prostatitis/chronic pelvic pain syndrome. Arch Ital Urol Androl Organo Uff Soc Ital Ecogr Urol E Nefrol Assoc Ric Urol 79:67–70

    Google Scholar 

  11. Shoskes DA (2012) The challenge of erectile dysfunction in the man with chronic prostatitis/chronic pelvic pain syndrome. Curr Urol Rep 13:263–267

    Article  PubMed  Google Scholar 

  12. Hao Z-Y, Li H-J, Wang Z-P et al (2011) The prevalence of erectile dysfunction and its relation to chronic prostatitis in Chinese men. J Androl 32:496–501

    Article  PubMed  Google Scholar 

  13. Chung S-D, Keller JJ, Lin H-C (2012) A case-control study on the association between chronic prostatitis/chronic pelvic pain syndrome and erectile dysfunction. BJU Int 110:726–730

    Article  PubMed  Google Scholar 

  14. Guay AT (2006) Testosterone and erectile physiology. Aging Male: Off J Int Soc Study Aging Male 9:201–206

    Article  CAS  Google Scholar 

  15. Shoskes DA, Prots D, Karns J et al (2011) Greater endothelial dysfunction and arterial stiffness in men with chronic prostatitis/chronic pelvic pain syndrome--a possible link to cardiovascular disease. J Urol 186:907–910

    Article  PubMed  Google Scholar 

  16. Shoskes DA, Berger R, Elmi A et al (2008) Muscle tenderness in men with chronic prostatitis/chronic pelvic pain syndrome: the chronic prostatitis cohort study. J Urol 179:556–560

    Article  PubMed Central  PubMed  Google Scholar 

  17. Screponi E, Carosa E, Di Stasi SM et al (2001) Prevalence of chronic prostatitis in men with premature ejaculation. Urology 58:198–202

    Article  CAS  PubMed  Google Scholar 

  18. Mo M-Q, Long L-L, Xie W-L et al (2014) Sexual dysfunctions and psychological disorders associated with type IIIa chronic prostatitis: a clinical survey in China. Int Urol Nephrol 46:2255–2261

    Article  PubMed  Google Scholar 

  19. Delavierre D, Sibert L, Rigaud J et al (2014) Painful ejaculation. Prog En Urol J Assoc Fr Urol Société Fr Urol 24:414–420

    Article  CAS  Google Scholar 

  20. Tran CN, Shoskes DA (2013) Sexual dysfunction in chronic prostatitis/chronic pelvic pain syndrome. World J Urol 31:741–746

    Article  PubMed  Google Scholar 

  21. Nickel JC, Elhilali M, Emberton M et al (2006) The beneficial effect of alfuzosin 10 mg once daily in “real-life” practice on lower urinary tract symptoms (LUTS), quality of life and sexual dysfunction in men with LUTS and painful ejaculation. BJU Int 97:1242–1246

    Article  CAS  PubMed  Google Scholar 

  22. Grimsley SJS, Khan MH, Jones GE (2007) Mechanism of phosphodiesterase 5 inhibitor relief of prostatitis symptoms. Med Hypotheses 69:25–26

    Article  CAS  PubMed  Google Scholar 

  23. Kong DH, Yun CJ, Park HJ et al (2014) The efficacy of mirodenafil for chronic prostatitis/chronic pelvic pain syndrome in middle-aged males. World J Mens Health 32:145–150

    Article  PubMed Central  Google Scholar 

  24. Cantoro U, Catanzariti F, Lacetera V et al (2013) Comparison of tamsulosin vs tamsulosin/sildenafil effectiveness in the treatment of erectile dysfunction in patients affected by type III chronic prostatitis. Arch Ital Urol Androl Organo Uff Soc Ital Ecogr Urol E Nefrol Assoc Ric Urol 85:109–112

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Vladimir Mouraviev .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Syed, J., Mouraviev, V. (2016). Andrologic Sequelae in Prostatitis Patients. In: Cai, T., Bjerklund Johansen, T. (eds) Prostatitis and Its Management. Springer, Cham. https://doi.org/10.1007/978-3-319-25175-2_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-25175-2_12

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-25173-8

  • Online ISBN: 978-3-319-25175-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics