A Two-Color Interacting Random Balls Model for Co-localization Analysis of Proteins

  • F. LavancierEmail author
  • C. Kervrann
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9389)


A model of two-type (or two-color) interacting random balls is introduced. Each colored random set is a union of random balls and the interaction relies on the volume of the intersection between the two random sets. This model is motivated by the detection and quantification of co-localization between two proteins. Simulation and inference are discussed. Since all individual balls cannot been identified, e.g. a ball may contain another one, standard methods of inference as likelihood or pseudolikelihood are not available and we apply the Takacs-Fiksel method with a specific choice of test functions.


Reference Model Point Process Yellow Fluorescence Protein Poisson Point Process Inference Procedure 
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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Inria, Centre Rennes Bretagne AtlantiqueRennesFrance
  2. 2.University of NantesNantesFrance

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