A Variety of Saccharide Binding-Sites



This chapter is devoted to discussion of protein binding–sites for saccharides for two main reasons. One is sentimental and self-serving and deals with J.B. Sumner who accidentally isolated concanavalin A when he proved in the twenties of the last century that enzymes are proteins (reference to Sumner is in Chap.  1). Concanavalin A is a protein where this author can mention his own contribution to the understanding of its structure and, in particular, its binding site for glucose and mannose. The other reason is lac-operon repressor that played such a crucial role in molecular biology and eventually provided a description in atomic detail of its interaction with DNA. A short summary of saccharide structure and nomenclature introduces this chapter. It describes as well a cellulose-binding protein that facilitates hydrolysis of crystalline cellulose by cellulases.


Identical Monomer Repressor Molecule Met84 Mutant Protein Heat Stability Residue Form Hydrogen Bond 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.CaesareaIsrael

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