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The Physiology of Microalgae pp 591–598Cite as

Algae Genome-Scale Reconstruction, Modelling and Applications

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Part of the book series: Developments in Applied Phycology ((DAPH,volume 6))

Abstract

Driven by revolutionary advances in high-throughput omics technologies, genome-scale metabolic reconstructions are a common denominator in systems biology and are available for a wide range of organisms. The constraint modelling formulation approach derived from the metabolic reconstructions have been successfully used to a number of applications including: metabolic engineering, biofuel research, genome functional annotation, omics data integration and in particular global pathway analysis. Recent advances have been made on plant and algae genome-scale metabolic reconstruction. In this book chapter we present the genome-scale reconstructions based on Chlamydomonas reinhardtii along with modelling formulation. We also give a few examples of the use of genome-scale models to algae biotechnological applications.

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Author information

Authors and Affiliations

  1. Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Building 75, Corner of College and Cooper Road, Brisbane, QLD, 4072, Australia

    Cristiana G. O. Dal’Molin & Lars K. Nielsen

Authors
  1. Cristiana G. O. Dal’Molin
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  2. Lars K. Nielsen
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Corresponding author

Correspondence to Cristiana G. O. Dal’Molin .

Editor information

Editors and Affiliations

  1. School of Veterinary and Life Sciences, Murdoch University, Algae R&D Centre, Murdoch, West Australia, Australia

    Michael A. Borowitzka

  2. School of Biological Sciences, Monash University, Clayton, Victoria, Australia

    John Beardall

  3. Division of Plant Biology, University of Dundee at the James Hutton, Dundee, United Kingdom

    John A. Raven

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© 2016 Springer International Publishing Switzerland

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Dal’Molin, C.G.O., Nielsen, L.K. (2016). Algae Genome-Scale Reconstruction, Modelling and Applications. In: Borowitzka, M., Beardall, J., Raven, J. (eds) The Physiology of Microalgae. Developments in Applied Phycology, vol 6. Springer, Cham. https://doi.org/10.1007/978-3-319-24945-2_22

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