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Optical Coherence Tomography of Vascular Disorders, Malformations, and Tumors

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Optical Coherence Tomography

Abstract

Optical coherence tomography (OCT), in conjunction with clinical examination, has become an important imaging modality to aid in both the diagnosis and treatment of ocular disorders. In this chapter, specific OCT findings of a variety of vascular diseases of the retina, choroid, and optic nerve are described through real clinical cases.

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References

  1. Wallow IH, Danis RP, Bindley C, Neider M. Cystoid macular degeneration in experimental branch retinal vein occlusion. Ophthalmology. 1998;95:1371–9.

    Article  Google Scholar 

  2. Sekiruyo T, Iida T, Sakai E, et al. Fundus autofluorescence and optical coherence tomography findings in branch retinal vein occlusion. J Ophthalmol. 2012;2012:638064.

    Google Scholar 

  3. Shroff D, Mehta DK, Arora R, et al. Natural history of macular status in recent-onset branch retinal vein occlusion: an optical coherence tomography study. Int Ophthalmol. 2008;28(4):261–8.

    Article  PubMed  Google Scholar 

  4. Spaide RF, Lee JK, Klancnik JM, Gross NE. Optical coherence tomography of branch retinal vein occlusion. Retina. 2003;23(3):343–7.

    Article  PubMed  Google Scholar 

  5. Kang HM, Chung EJ, Kim YM, Koh HJ. Spectral-domain optical coherence tomography (SD-OCT) patterns and response to intravitreal bevacizumab therapy in macular edema associated with branch retinal vein occlusion. Graefs Ach Clin Exp Ophthalmol. 2013;251(2):501–8.

    Article  CAS  Google Scholar 

  6. Kim CS, Shin KS, Lee HJ, Jo YJ, Kim JY. Sectoral retinal nerve fiber layer thinning in branch retinal vein occlusion. Retina. 2014;34(3):525–30.

    Google Scholar 

  7. Castro LV, Yeung L, Castro LC, et al. Correlation between spectral domain optical coherence tomography findings and visual outcomes in central retinal vein occlusion. Clin Ophthalmol. 2001;5:299–305.

    Google Scholar 

  8. Martinet V, Guigui B, Glacet-Bernard A, et al. Macular edema in central retinal vein occlusion: correlation between optical coherence tomography, angiography, and visual acuity. Int Ophthalmol. 2012;32(4):369–77.

    Article  PubMed  Google Scholar 

  9. Rosenfeld PJ, Fung AE, Puliafito CA. Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin) for macular edema from central retinal vein occlusion. Ophthalmic Surg Lasers Imaging. 2005;36(4):336–9.

    PubMed  Google Scholar 

  10. Cella W, Avila M. Optical coherence tomography as a means of evaluating acute ischaemic retinopathy in branch retinal artery occlusion. Acta Ophtalmol Scand. 2007;85:799–801.

    Article  Google Scholar 

  11. Karacorlu M, Ozdemir H, Arf KS. Optical coherence tomography findings in branch retinal artery occlusion. Eur J Ophthalmol. 2006;16(2):352–3.

    CAS  PubMed  Google Scholar 

  12. Shah VA, Wallace B, Sabetes NR. Spectral domain optical coherence tomography findings of acute branch retinal artery occlusion from calcific embolus. Indian J Ophthalmol. 2010;58(6):523–4.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Chu YK, Hong YT, Byeon SH, Kwon OW. In vivo detection of acute ischemic damages in retinal arterial occlusion with optical coherence tomography. Retina. 2013;33(10):2110–7.

    Article  PubMed  Google Scholar 

  14. Falkenberry SM, Ip MS, Blodi BA, Gunther JB. Optical coherence tomography findings in central retinal artery occlusion. Ophthalmic Surg Lasers Imaging. 2006;37(6):502–5.

    PubMed  Google Scholar 

  15. Chen SN, Hwang JF, Chen YT. Macular thickness measurements in central retinal artery occlusion by optical coherence tomography. Retina. 2011;31(4):730–7.

    Article  PubMed  Google Scholar 

  16. Kothari MT, Maiti A. Ophthalmic artery occlusion: a cause of unilateral visual loss following spine surgery. Indian J Ophthalmol. 2007;55(5):401–2.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Gaudric A, Coscas G, Bird AC. Choroidal ischemia. Am J Ophthalmol. 1982;94(4):489–98.

    Article  CAS  PubMed  Google Scholar 

  18. Kopsachilis N, Pefkianaki M, Marinescu A, Sivaprasad S. Giant cell arteritis presenting as choroidal infarction. Case Rep Ophthalmol Med. 2013;2013:597398.

    PubMed  PubMed Central  Google Scholar 

  19. Iida T, Spaide RF, Kantor J. Retinal and choroidal arterial occlusion in Wegener’s granulomatosis. Am J Ophthalmol. 2002;133:151–2.

    Article  PubMed  Google Scholar 

  20. Viestenz A, Kuchle M. Choroidal ischaemic infarction following ocular contusion with small framed spectacles: Hutchinson-Siegrist-Neubauer- syndrome. Br J Ophthalmol. 2002;86(11):1319.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Contreras I, Noval S, Rebolleda G, Munoz-Negrete FJ. Follow-up of nonarteritic anterior ischemic optic neuropathy with optical coherence tomography. Ophthalmology. 2007;114(12):2338–44.

    Article  PubMed  Google Scholar 

  22. Tsujikawa A, Sakamoto A, Ota M, et al. Retinal structural changes associated with retinal arterial macroaneurysm examined with optical coherence tomography. Retina. 2009;29(6):782–92.

    Article  PubMed  Google Scholar 

  23. Lee EK, Woo SJ, Ahn A, Park KH. Morphologic characteristics of retinal arterial macroaneurysm and its regression pattern on spectral-domain optical coherence tomography. Retina. 2011;31(10):2095–101.

    Article  PubMed  Google Scholar 

  24. Goldenberg D, Soiberman U, Loewenstein A, Goldstein M. Heidelberg spectral-domain optical coherence tomographic findings in retinal arterial macroaneurysm. Retina. 2012;32(5):990–5.

    Article  PubMed  Google Scholar 

  25. Takahashi K, Kishi S. Serous macular detachment associated with retinal arterial macroaneurysm. Jpn J Ophthalmol. 2006;50(5):460–4.

    Article  PubMed  Google Scholar 

  26. Savar A, Vavvas D. Optical coherence tomography appearance of a retinal artery macroaneurysm. Ophthalmic Surg Lasers Imaging. 2009;40(4):403–4.

    Article  PubMed  Google Scholar 

  27. Horgan N, Shields CL, Mashayekhi A, Shields JA. Classification and treatment of radiation maculopathy. Curr Opin Ophthalmol. 2010;21:233–8.

    Article  PubMed  Google Scholar 

  28. Hong KH, Chang SD. A case of radiation retinopathy of the left eye after radiation therapy of right brain metastasis. Korean J Ophthalmol. 2009;23(2):114–7.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Levitz LM. The use of optical coherence tomography to determine the severity of radiation retinopathy. Ophthalmic Surg Lasers Imaging. 2005;36(5):410–1.

    PubMed  Google Scholar 

  30. Shah SU, Shields CL, Bianciotto CG, Iturralde J, et al. Intravitreal bevacizumab at 4-month intervals for prevention of macular edema after plaque radiotherapy of uveal melanoma. Ophthalmology. 2014;121(1):269–75.

    Article  PubMed  Google Scholar 

  31. Purtscher O. Noch unbekannte befunde nach Schadeltrauma. Ber Dtsch Ophthalmol Ges. 1910;36:294–301.

    Google Scholar 

  32. Agrawal A, McKibbon MA. Purtscher’s and Purtscher-like retinopathies: a review. Surv Ophthalmol. 2006;51:129–36.

    Article  PubMed  Google Scholar 

  33. Agrawal A, McKibbin M. Purtscher’s retinopathy: epidemiology, clinical features, and outcome. Br J Ophthalmol. 2007;91(11):1456–9.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Lauer AK, Klein ML, Koverik D, Palmer EA. Hemolytic uremic syndrome associated with Purtscher-like retinopathy. Arch Ophthalmol. 1998;116(8):1119–20.

    CAS  PubMed  Google Scholar 

  35. Paunescu LA, Ko TH, Duker JS, et al. Idiopathic juxtafoveal retinal telangiectasis: New findings by ultrahigh-resolution optical coherence tomography. Ophthalmology. 2006;113:48–57.

    Article  PubMed  Google Scholar 

  36. Cohen SM, Cohen ML, El-Jabali F, Paulter SE. Optical coherence tomography findings in nonproliferative group 2a idiopathic juxtafoveal retinal telangiectasis. Retina. 2007;27:59–66.

    Article  PubMed  Google Scholar 

  37. Sanchez JG, Garcia RA, Wu L, et al. Optical coherence tomography characteristics of group 2A idiopathic parafoveal telangiectasis. Retina. 2007;27:1214–20.

    Article  PubMed  Google Scholar 

  38. Shukla D, Naresh KB, Kim R. Optical coherence tomography findings in valsalva retinopathy. Am J Ophthalmol. 2005;140(1):134–6.

    Article  PubMed  Google Scholar 

  39. Ho LY, Abdelghani WM. Valsalva retinopathy associated with the choking game. Semin Ophthalmol. 2007;22(2):63–4.

    Article  PubMed  Google Scholar 

  40. Zou M, Gao S, Zhang J, Zhang M. Persistent unsealed internal limiting membrane after Nd:YAG laser treatment for valsalva retinopathy. BMC Ophthalmol. 2013;13:15.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Park KA, Oh SY. Analysis of spectral-domain optical coherence tomography in preterm children: retinal layer thickness and choroidal thickness profiles. Invest Ophthalmol Vis Sci. 2012;53(11):7201–7.

    Article  PubMed  Google Scholar 

  42. Lee AC, Maldonado RS, Sarin N, et al. Macular features from spectral domain optical coherence tomography as an adjunct to indirect ophthalmoscopy in retinopathy of prematurity. Retina. 2011;31(8):1470–82.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Recchia FM, Recchia CC. Foveal dysplasia evident by optical coherence tomography in patients with a history of retinopathy of prematurity. Retina. 2007;27(9):1221–6.

    Article  PubMed  Google Scholar 

  44. Dubis AM, Subramaniam CD, Godara P, et al. Subclinical macular findings in infants screened for retinopathy of prematurity with spectral-domain optical coherence tomography. Ophthalmology. 2003;120(8):1665–71.

    Article  Google Scholar 

  45. Day S, Maldonado R, Toth C. Preretinal and intraretinal exudates in familial exudative vitreoretinopathy. Retina. 2011;31(1):193–4.

    Article  Google Scholar 

  46. Shimouchi A, Takahashi A, Nagaoka T, Ishibazawa A, Yoshida A. Vitreomacular interface in patients with familial vitreoretinopathy. Int Ophthalmol. 2013;33(6):711–5.

    Article  PubMed  Google Scholar 

  47. Otani T, Yasuda K, Aizawa N, et al. Over 10 years follow-up of Coats’ disease in adulthood. Clin Ophthalmol. 2011;5:1729–32.

    PubMed  PubMed Central  Google Scholar 

  48. Henry CR, Berrocal AM, Hess DJ, Murray TG. Intraoperative spectral-domain optical coherence tomography in coats’ disease. Ophthalmic Surg Lasers Imaging. 2012;26(43):e80–4.

    Google Scholar 

  49. Kamppeter B, Jonas JB. Central serous chorioretinopathy imaged by optical coherence tomography. Arch Ophthalmol. 2003;121(5):742–3.

    Article  PubMed  Google Scholar 

  50. Montero JA, Ruiz-Moreno JM. Optical coherence tomography characterization of idiopathic central serous chorioretinopathy. Br J Ophthalmol. 2005;89(5):562–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  51. Nicholson B, Noble J, Forooghian F, Meyerle C. Central serous chorioretinopathy: update on pathophysiology and treatment. Surv Ophthalmol. 2013;58(2):103–26.

    Article  PubMed  PubMed Central  Google Scholar 

  52. Yang L, Jonas JB, Wenmin W. Optical coherence tomography-assisted enhanced depth imaging of central serous chorioretinopathy. Invest Ophthalmol Vis Sci. 2013;54(7):4659–65.

    Article  PubMed  Google Scholar 

  53. Ojima Y, Hangai M, Sakamoto A, et al. Improved visualization of polypoidal choroidal vasculopathy lesions using spectral-domain optical coherence tomography. Retina. 2009;29(1):52–9.

    Article  PubMed  Google Scholar 

  54. Nagase S, Miura M, Makita S, et al. High-penetration optical coherence tomography with enhanced depth imaging of polypoidal choroidal vasculopathy. Ophthalmic Surg Lasers Imaging. 2012;9(43):e5–9.

    Google Scholar 

  55. Sayanagi K, Gomi F, Ikuno Y, et al. Comparison of spectral-domain and high-penetrance OCT for observing morphologic changes in age-related macular degeneration and polypoidal choroidal vasculopathy. Graefes Arch Clin Exp Ophthalmol. 2014;252(1):3–9.

    Article  PubMed  Google Scholar 

  56. Andrade RE, Farah ME, Costa RA, Belfort R. Optical coherence tomography findings in macular cavernous hemangioma. Acta Ophthalmol Scand. 2004;83:267–8.

    Article  Google Scholar 

  57. Shields CL, Ma M, Shields JA. Review of optical coherence tomography for intraocular tumors. Curr Opin Ophthalmol. 2005;16(3):141–54.

    Article  PubMed  Google Scholar 

  58. Heimann H, Imor F, Damato B. Imaging of retinal and choroidal vascular tumours. Eye (Lond). 2013;27(2):208–16. doi:10.1038/eye.2012.251. Epub 2012 Nov 30.

    Article  CAS  Google Scholar 

  59. Shields CL, Mashayekhi A, Luo CK, Materin MA, Shields JA. Optical coherence tomography in children: analysis of 44 eyes with intraocular tumors and simulating conditions. J Pediatr Ophthalmol Strabismus. 2004;41(6):338–44.

    PubMed  Google Scholar 

  60. Chalam KV, Murthy RK, Gupta SK, Brar VS. Spectral domain optical coherence tomography guided photodynamic therapy for choroidal hemangioma: a case report. Cases J. 2009;2:8778–82.

    Article  PubMed  PubMed Central  Google Scholar 

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Acknowledgments

Dr. Carol L. Shields, MD

Dr. Jerry Shields, MD

Dr. William Benson, MD

Dr. Ehsan Rahimy, MD

Dr. Robert Sergott, MD

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Correspondence to Margaret A. Greven MD .

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Greven, M.A., Greven, C.M. (2016). Optical Coherence Tomography of Vascular Disorders, Malformations, and Tumors. In: Girach, A., Sergott, R. (eds) Optical Coherence Tomography. Springer, Cham. https://doi.org/10.1007/978-3-319-24817-2_4

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  • DOI: https://doi.org/10.1007/978-3-319-24817-2_4

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