Abstract
Lifestyle medicine, emphasizing prevention as well as therapy, plays a central role in the understanding and treatment of gastrointestinal (GI) illnesses. This chapter will focus upon specific GI diseases associated with clinical symptoms related to disturbed immune function. Attention will be directed to the pathophysiologic underpinning of the disease process and the role of lifestyle applications preventing or ameliorating the illness. Such consideration will be given to GI reflux disease, peptic ulcer and gastritis, gall bladder disease, pancreatitis, Celiac disease, irritable bowel syndrome, and inflammatory bowel diseases.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Abbreviations
- ADHD:
-
Attention deficit hyperactivity disorder
- BMI:
-
Body Mass Index
- CD:
-
Crohn’s disease
- CMV:
-
Cytomegalovirus
- DNA:
-
Deoxyribonucleic acid
- EKG:
-
Electrocardiogram
- FISH:
-
Fluorescence in situ hybridization
- FODMAPs:
-
Fermentable oligo-, di- and mono-saccharides and polyols
- GERD:
-
Gastroesophageal reflux disease
- GI:
-
Gastrointestinal
- HIV:
-
Human immunodeficiency virus
- IBDs:
-
Inflammatory bowel diseases
- IBS:
-
Irritable bowel syndrome
- LES:
-
Lower esophageal sphincter
- NCGS:
-
Non-celiac gluten sensitivity
- NSAIDs:
-
Nonsteroidal anti-inflammatory agents
- n-3 FA:
-
Omega-3 fatty acids
- n-6 FA:
-
Omega-6 fatty acids
- PCR:
-
Polymerase chain reaction
- PUFA:
-
Polyunsaturated fatty acids
- RD:
-
Registered dietitian
- RNA:
-
Ribonucleic acid
- SCFA:
-
Short-chain fatty acids
- tTG:
-
Tissue transglutaminase
- tTG IgA:
-
Tissue transglutaminase immunoglobulin A
- tLESRs:
-
Transient lower esophageal sphincter relaxations
- T-RELP:
-
Terminal restriction fragment length polymorphism
- UC:
-
Ulcerative colitis
- UDCA:
-
Ursodeoxycholic acid
References
El-Serag HB, Ergun GA, Pandolfino J, et al. Obesity increases oesophageal acid exposure. Gut. 2007;56:749–55.
Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984;2:1311–5.
Lee SA, Kang D, Shim KN, et al. Effect of diet and Helicobacter pylori infection to the risk of early gastric cancer. J Epidemiol. 2003;13:162–8.
Allison MC, Howaston AG, Torrance CJ, et al., Gastrointestinal damage associated with the use of non-steroidal anti-inflammatory drugs. N Engl J Med. 1992;327:749–54.
Everhart JE, Khare M, Hill M, Maurer KR. Prevalence and ethnic differences in gall bladder disease in the United States. Gastroenterology. 1999;117:632–9.
Heaton KW, Braddon FE, Mountford RA, et al. Symptomatic and silent gallstones in the community. Gut. 1991;32:316–20.
Ransohoff DF, Gracie WA, Wolfenson LB, Neuhauser D. Prophylactic cholecystectomy or expectant management for silent gallstones. A decision analysis to assess survival. Ann Int Med. 1983;99:199–204.
Shaffer EA. Gallstone disease: epidemiology of gallbladder stone disease. Best Pract Res Clin Gastroenterol. 2006;20:981–96.
Badalov N, Baradarian R, Iswara K, et al. Drug-induced pancreatitis: an evidence-based review. Clin Gastroenterol Hepatol. 2007;5:648–61.
Forsmark CE, Baillie J. AGA Institute Councl Practice and Economics Committee, AGA Institute Governing Board. AGA Institute technical review on acute pancreatitis. Gastroenterology. 2007;132:2022.
Otsuki M, Tashiro M. Chronic pancreatitis and pancreatic cancer, lifestyle-related diseases. Intern Med. 2007;46:109–13.
Rostom A, Murray JA, Kagnoff ME. American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology. 2006;131:l981–2002.
Mansueto P, Seidita A, D’Alcamo A, Carroccio A. Non-celiac gluten sensitivity: literature review. J Am Coll Nutr. 2014;33(1):39–54.
Brandt LJ, Chey WD, et al. American College of Gastroenterology Task Force on Irritable Bowel Syndrome, An evidence-based position statement on the management of irritable bowel syndrome. Am J Gastroenterol. 2009;104 Suppl 1:S1.
Chey WY, Jin HO, Lee MH, et al. Colonic motility abnormality in patients with irritable bowel syndrome. Am J Gastroenterol. 2001;96:1499–506.
Liebregts T, Adam B, Bredack C, et al. Immune activation in patients with irritable bowel syndrome. Gastroenterology. 2007;132:913–20.
Wang LH, Fang XC, Pan GZ. Bacillary dysentery as a causative factor of irritable bowel syndrome and its pathogenesis. Gut. 2004;53:1096–101.
Jeffery IB, O’Toole PW, Ohman L, et al. An irritable bowel subtype defined by species specific alterations in faecal microbiota. Gut. 2012;61:997–1006.
Chey WD. The role of food in the functional gastrointestinal disorders: introduction to a manuscript series. Am J Gastroenterol. 2013;108:694–7.
Gibson PR, Shepherd SJ. Food choice as a key management strategy for functional gastrointestinal symptoms. Am J Gastroenterol. 2012;107:657–66.
Amre AK, D’souza S, Morgan K, Seidman G, et al. Imbalances in dietary consumption of fatty acids, vegetables, and fruits are associated with risk for Crohn’s disease in children. Am J Gastroenterol. 2007;102:2016–25.
Hou JK, Abraham B, El-Serag H. Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature. Am J Gastroenterol. 2011;106:563–73.
Nagalingam NA, Lynch SV. Role of microbiota in inflammatory bowel diseases. Inflamm Bowel Dis. 2012;18:968–80.
Sekirov I, Russell SL, Atunes CM, Finlay BB. Gut microbiota in health and disease. Physiol Rev. 2010;90:859–904.
Tannock GW. New Perceptions of the gut microbiota: implications for future research. Gastroenterol Clin N Am. 2005;41:361–82.
Chatterjess S, Kar P, Das T, et al. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and bifidobacterium BB-12 for prevention of antibiotic-associated diarrhea. J Assoc Physicians India. 2013;61:708–12.
Abbas Z, Yakoob J, Jafri W, et al. Cytokine and clinical response to Saccharomyces boulardii therapy in diarrhea-dominant irritable bowel syndrome: a randomized trial. Eur J Gastroenterol Hepatol. 2014;26:630–9.
Bajaj JS, Heuman DM, Hylemon PB, et al. Randomised clinical trial: lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis. Ailment Pharmacol Ther. 2014;39:1113–25.
Aoki T, Asahara T, Matsumoto K, et al. Effects of the continuous intake of a milk drink containing Lactobacillus casei strain Shirota on abdominal symptoms, fecal microbiota, and metabolites in gastrectomized subjects. Scand J Gastroenterol. 2014;49:552–63.
Hegar B, Hutapea EI, Advani N, et al. A double-blind placebo-controlled randomized trial on probiotics in small bowel bacterial overgrowth in children treated with omeprazole. J Pediatr. 2013;89:381–7.
Shao F, Xin FZ, Yang CG, et al. The impact of microbial immune enteral nutrition on the patients with acute radiation enteritis in bowel function and immune status. Cell Biochem Biophys. 2014;69:357–61.
Virk A, Mandrekar J, Berbari EF, et al. A randomized, double blind, placebo-controlled trial of an oral symbiotic (AKSB) for prevention of travelers’ diarrhea. J Travel Med. 2013;20:88–94.
Woodward GA, Encarnacion B, Downey JR, et al. Probiotics improve outcomes after Roux-en-Y gastric bypass surgery: a prospective randomized trial. J Gastrointest Surg. 2009;13:1198–204.
Mekkes MC, Weenen TC, Brummer RJ, et al. The development of probiotic treatment in obesity: a review. Benef Microbes. 2014;5:19–28.
Gomes AC, Bueno AA, de Souza RG, et al. Gut microbiota, probiotics and diabetes. Nutr J. 2014;13:60. doi:10.1186/1475-2891-13-60.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Friedman, G. (2016). Gastroenterology Disease and Lifestyle Medicine. In: Mechanick, J., Kushner, R. (eds) Lifestyle Medicine. Springer, Cham. https://doi.org/10.1007/978-3-319-24687-1_30
Download citation
DOI: https://doi.org/10.1007/978-3-319-24687-1_30
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-24685-7
Online ISBN: 978-3-319-24687-1
eBook Packages: MedicineMedicine (R0)