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Cerebrovascular Involvement in Neurobrucellosis and Mycotic Aneurysms

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Neurobrucellosis

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Abstract

Cerebrovascular manifestations are uncommon features of brucellosis especially as the presenting feature. The major mechanisms of stroke in neurobrucellosis are mycotic aneurysm, embolism from cardiac vegetations, and Brucella-associated vasculitis. Spread of inflammation from adjacent meninges may lead to cerebral venous sinus thrombosis. Common clinical presentation includes stroke, transient ischemic attack, seizures, and symptoms of increased intracranial pressure along with features of meningeal irritation and systemic features. Neurotuberculosis, primary central nervous system lymphoma, demyelination, neurosyphilis, and vasculitis are the common differential diagnoses. There are no evidence-based guidelines for the management of cerebrovascular complications of neurobrucellosis. The usual clinical practice is medical management followed by surgical/endovascular treatment if required.

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Abbreviations

BA:

Basilar artery

CNS:

Central nervous system

CSF:

Cerebrospinal fluid

CVT:

Cerebral venous sinus thrombosis

ICH:

Intracerebral hemorrhage

MCA:

Middle cerebral artery

SAH:

Subarachnoid hemorrhage

TIA:

Transient ischemic attack

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Author information

Authors and Affiliations

  1. Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

    Dheeraj Khurana MD, Roopa Rajan MD & Venugopalan Y. Vishnu MD

  2. Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey

    Ahmet Tuncay Turgut MD

Authors
  1. Dheeraj Khurana MD
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  2. Roopa Rajan MD
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  3. Ahmet Tuncay Turgut MD
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  4. Venugopalan Y. Vishnu MD
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Corresponding author

Correspondence to Dheeraj Khurana MD .

Editor information

Editors and Affiliations

  1. Department of Neurosurgery, Adnan Menderes University School of Medicine, Aydin, Turkey

    Mehmet Turgut

  2. Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon

    Fuad Sami Haddad

  3. School of Medicine and Surgery, University of Naples Federico II School of Medicine and Surgery, Naples, Italy

    Oreste de Divitiis

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Khurana, D., Rajan, R., Turgut, A.T., Vishnu, V.Y. (2016). Cerebrovascular Involvement in Neurobrucellosis and Mycotic Aneurysms. In: Turgut, M., Haddad, F., de Divitiis, O. (eds) Neurobrucellosis. Springer, Cham. https://doi.org/10.1007/978-3-319-24639-0_9

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  • DOI: https://doi.org/10.1007/978-3-319-24639-0_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-24637-6

  • Online ISBN: 978-3-319-24639-0

  • eBook Packages: MedicineMedicine (R0)

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