Abstract
A thorough search of the literature reveals a total of 21 cases of brain Brucella abscess and brucelloma. In this chapter, these were reviewed and tabulated and their incidence, the ways of brain invasion, and their distribution as to sex, age, lateralization, localization, multiplicity, size, signs and symptoms, laboratory findings, and pathology were discussed.
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Abbreviations
- ESR:
-
Erythrocyte sedimentation rate
- CNS:
-
Central nervous system
- CSF:
-
Cerebrospinal fluid
- CT:
-
Computed tomography
- MRI:
-
Magnetic resonance imaging
- STA:
-
Serum tube agglutination
References
Al-Eissa YA (1993) Unusual suppurative complications of brucellosis in children. Acta Paediatr 82:987–992
Al Deeb SM, Yaqub BA, Sharif HS, Phadke JG (1989) Neurobrucellosis: clinical characteristics, diagnosis and outcome. Neurology 39:498–501
Al-Freihi HM, Al-Mohaya SA, Al-Mohsen MA, Ibrahim EM, Al-Souhaibani MO, Twum-Danso K, Idrissi HY (1986) Brucellosis in Saudi Arabia: diverse manifestations of an important cause of pyrexial illness. Ann Saudi Med 6:95–99
Al-Sous MW, Bohlega S, Al-Kawi MZ, Alwatban J, McLean DR (2004) Neurobrucellosis: clinical and neuroimaging correlation. AJNR Am J Neuroradiol 25:395–401
Ariza J, Gudiol F, Pallares R, Rufi G, Fernandez-Viladrich P (1985) Comparative trial of rifampin-doxycycline versus tetracycline-streptomycin in the therapy of human brucellosis. Antimicrob Agents Chemother 28:548–551
Ayala-Gaytán JJ, Ortegon-Baqueiro H, de la Maza M (1989) Brucella melitensis cerebellar abscess. J Infect Dis 160:730–732
Benjamin B, Annobil SH (1992) Childhood brucellosis in southwestern Saudi Arabia: a 5-year experience. J Trop Pediatr 38:167–172
Budnik I, Fuchs I, Shelef I, Krymko H, Greenberg D (2012) Case report: unusual presentations of pediatric neurobrucellosis. Am J Trop Med Hyg 86:258–260
Carrasco-Moro R, Pedrosa-Sánchez M, Garcia Navarrete E, Pascual-Garvi JM, Minervini-MarÃn M, Sola RG (2006) Refractory epilepsy as the presenting symptom of a brucellar brain abscess. Revista NeurologÃa 43:729–732
Ceran N, Turkoglu R, Erdem I, Inan A, Engin D, Tireli H, Goktas P (2011) Neurobrucellosis: clinical, diagnostic, therapeutic features and outcome. Unusual clinical presentations in an endemic region. Braz J Infect Dis 15:52–59
Cooper CW (1991) The epidemiology of human brucellosis in a well defined urban population in Saudi Arabia. J Trop Med Hyg 94:416–422
Demiroğlu YZ, Turunç T, Karaca S, Arlıer Z, Alışkan H, Colakoğlu S, Arslan H (2011) Neurological involvement in brucellosis; clinical classification, treatment and results. Mikrobiyol Bul 45:401–410
Galanakis E, Bourantas KL, Leveidiotou S, Lapatsanis PD (1996) Childhood brucellosis in north-western Greece: a retrospective analysis. Eur J Pediatr 155:1–6
Gul HC, Erdem H, Bek S (2009) Overview of neurobrucellosis: a pooled analysis of 187 cases. Int J Infect Dis 13:e339–e343
Gul HC, Erdem H, Gorenek L, Ozdag MF, Kalpakci Y, Avci IY, Besirbellioglu BA, Eyigum CP (2008) Management of neurobrucellocis: an assessment of 11 cases. Intern Med 47:995–1001
Gündes S, Meric M, Willke A, Erdenlig S, Koc K (2004) A case of intracranial abscess due to Brucella melitensis. Int J Infect Dis 8:379–381
Gür A, Geyik MF, Dikici B, Nas K, Cevik R, Sarac J, Hosoglu S (2003) Complications of brucellosis in different age groups: a study of 283 cases in southeastern Anatolia of Turkey. Yonsei Med J 44:33–44
Guven T, Ugurlu K, Ergonul O, Celikbas AK, Gök SE, Comoglu S, Baykam N, Dokuzoguz B (2013) Neurobrucellosis: clinical and diagnostic features. Clin Infect Dis 56:1407–1412
Guvenc H, Kocabay K, Okten A, Bektas S (1989) Brucellosis in a child complicated with multiple brain abscesses. Scand J Infect Dis 21:333–336
Haddad FS, Bitar E, Haddad GF (2006) A rare, late complication in a hemispherectomized patient: a brucella abscess in the contra lateral hemisphere. Pan Arab J Neurosurg 10:70–74
Haddad FS, Fahl M, Haddad SF (1989) Brucellar spondylitis: review of 21 cases. J Med Liban 37:4–8
Haji-Abdolbagi M, Rasooli-Nejad M, Jafari S, Hasibi M, Soudbakhsh A (2008) Clinical and laboratory findings in neurobrucellosis: review of 31 cases. Arch Iran Med 11:21–25
Hatipoglu CA, Yetkin A, Ertem GT, Tulek N (2004) Unusual clinical presentations of brucellosis. Scand J Infect Dis 36:695–698
Kalelioğlu M, Ceylan S, Koksal I, Kuzeyli K, Akturk F (1990) Brain abscess caused by Brucella abortus and Staphylococcus aureus in a child. Infection 18:386–387
Keihani-Douste Z, Daneshjou K, Ghasemi M (2006) A quadriplegic child with multiple brain abscesses: case report of neurobrucellosis. Med Sci Monit 12:CS119–CS122
Khuri-Bulos N, Daoud AH, Azab SM (1993) Treatment of childhood brucellosis: results of a prospective trial on 113 children. Pediatr Infect Dis J 12:377–381
Kizilkilic O, Turunc T, Yildirim T, Demiroglu YZ, Hurcan C, Uncu H (2005) Successful medical treatment of intracranial abscess caused by Brucella spp. J Infect 51:77–80
Koc K (2006) Brucellar brain abscess and bilateral arachnoid cysts, unilaterally complicated by subdural haematoma. J Clin Neurosci 13:485–487
Kochar DK, Agarwal N, Jain N, Sharma BV, Rastogi A, Meena CB (2000) Clinical profile of neurobrucellosis-a report on 12 cases from Bikaner (North-West India). J Assoc Physicians India 48:376–380
Lubani MM, Dudin KI, Araj GF, Manandhar DS, Rashid FY (1989) Neurobrucellosis in children. Pediatr Infect Dis J 8:79–82
Martınez-Chamorro E, Muñoz A, Esparza J, Muñoz MJ, Giangaspro E (2002) Case report; focal cerebral involvement by neurobrucellosis: pathological and MRI findings. Eur J Radiol 43:28–30
Miguel PS, Fernandez G, Vasallo FJ, Hortas M, Lorenzo JR, Rodriguez I, Ortiz-Rey JA, Anton I (2006) Neurobrucellosis mimicking cerebral tumor: case report and literature review. Clin Neurol Neurosurg 108:404–406
Santini C, Baiocchi P, Berardelli A, Venditti M, Serra P (1994) A case of brain abscess due to Brucella melitensis. Clin Infect Dis 19:977–978
Sohn AH, Probert WS, Glaser CA, Gupta N, Bollen AW, Wong JD, Grace EM, McDonald WC (2003) Human neurobrucellosis with intracerebral granuloma caused by a marine mammal Brucella spp. Emerg Infect Dis 9:485–488
Solmaz Ç, Mustafa H, Melda S (2010) Brucellar brain abscess in a child. J Pediatr Inf 4:89–91
Stranjalis G, Singounas E, Boutsikakis I, Saroglou G (2000) Chronic intracerebral Brucella abscess. Case illustration. J Neurosurg 92:189
Tanir G, Tufekci SB, Tuygun N (2009) Presentation, complications, and treatment outcome of brucellosis in Turkish children. Pediatr Int 51:114–119
Tonekaboni SH, Karimi A, Armin S, Khase LA, Sabertehrani AS (2009) Neurobrucellosis: a partially treatable cause of vision loss. Pediatr Neurol 40:401–403
Trifiletti RR, Restivo DA, Pavone P, Guifrida S, Parano E (2000) Diabetes insipidus in neurobrucellosis. Clin Neurol Neurosurg 102:163
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Haddad, F.S. (2016). Brucella Abscess and Granuloma of the Brain. In: Turgut, M., Haddad, F., de Divitiis, O. (eds) Neurobrucellosis. Springer, Cham. https://doi.org/10.1007/978-3-319-24639-0_7
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