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Joint Involvement in Systemic Lupus Erythematosus

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Connective Tissue Disease

Part of the book series: Rare Diseases of the Immune System ((RDIS))

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Abstract

Articular involvement is very frequent in systemic lupus erythematosus (SLE): in up to 50 % of patients with SLE, joint involvement is the first manifestation of the disease, whereas during the course of SLE, it is almost always present. Articular signs include arthralgia and/or arthritis. Arthralgia, which is defined as the presence of joint pain in the absence of clear synovitis, erosion, or deformities, is very frequent both at the onset and during the course of the disease. Arthritis in the course of SLE can be acute, subacute, and/or chronic and is often detected in up to 90 % of the cases.

This chapter will review joint involvement in SLE, focusing on classification, diagnosis, and treatment.

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Authors and Affiliations

  1. CMID – Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network of Rare Diseases of Piedmont and Aosta Valley, Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Giovanni Bosco Hospital, University of Turin, Turin, 10154, Italy

    Daniela Rossi & Vittorio Modena

  2. Division of Rheumatology, Department of Locomotor System, ASL3 Genovese, Genoa, Italy

    G. Bianchi

  3. Department of Rheumatology, Mauriziano Hospital, Turin, 10128, Italy

    Raffaele Pellerito

  4. CMID – Center of Research of Immunopathology and Rare Diseases, Coordinating Center of the Network of Rare Diseases of Piedmont and Aosta Valley, Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Giovanni Bosco Hospital, and University of Turin, Turin, 10154, Italy

    Dario Roccatello

  5. SCDU Nephrology and Dialysis, Giovanni Bosco Hospital, and University of Turin, Turin, Italy

    Dario Roccatello

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  1. Daniela Rossi
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  2. Vittorio Modena
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  3. G. Bianchi
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  4. Raffaele Pellerito
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  5. Dario Roccatello
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Correspondence to Vittorio Modena .

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Editors and Affiliations

  1. Giovanni Bosco Hospital, Center of Immunopathology/Rare Dise, Torino, Torino, Italy

    Dario Roccatello

  2. University of Florence, Florence, Italy

    Lorenzo Emmi

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Rossi, D., Modena, V., Bianchi, G., Pellerito, R., Roccatello, D. (2016). Joint Involvement in Systemic Lupus Erythematosus. In: Roccatello, D., Emmi, L. (eds) Connective Tissue Disease. Rare Diseases of the Immune System. Springer, Cham. https://doi.org/10.1007/978-3-319-24535-5_6

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