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Patient Selection for Hypofractionated Whole Breast Radiation Therapy for Treatment of Early-Stage Breast Cancer

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Abstract

Hypofractionated whole breast irradiation (HWBI) has been firmly established as a standard of care for postlumpectomy radiation for early-stage breast cancer, based in large part on the favorable 10-year results of prospective randomized trials from Canada and the United Kingdom. In the United States and other countries, the question now is no longer whether or not to do hypofractionation, but rather to which patients this should be offered instead of conventional fractionation. This chapter will review the criteria for patient selection to be used for the inclusion and exclusion of patients for whole breast hypofractionation in clinical practice today.

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Authors and Affiliations

  1. Department of Radiation Oncology, Perelman Center for Advanced Medicine, Perelman School of Medicine of the University of Pennsylvania, TRC 4 West 3400 Civic Center Blvd, Philadelphia, PA, 19104, USA

    Gary M. Freedman MD

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  1. Gary M. Freedman MD
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Correspondence to Gary M. Freedman MD .

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Editors and Affiliations

  1. Department of Radiation Oncology, Virginia Commonwealth Univ Sch. Medicine Department of Radiation Oncology, RICHMOND, Virginia, USA

    Douglas W Arthur

  2. Michigan Healthcare Professionals, 21st Century Oncology Michigan Healthcare Professionals, Farmington Hills, Michigan, USA

    Frank A. Vicini

  3. Dept. Rad Oncol, Tufts Univ. School Med, Alpert Medical School Brown University Dept. Rad Oncol, Tufts Univ. School Med, BOSTON, Massachusetts, USA

    David E. Wazer

  4. Dept. of Radiation Oncology, Rutgers Can State Univ. New Jer Sch. Med Dept. of Radiation Oncology, NEW BRUNSWICK, New Jersey, USA

    Atif J. Khan

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Freedman, G.M. (2016). Patient Selection for Hypofractionated Whole Breast Radiation Therapy for Treatment of Early-Stage Breast Cancer. In: Arthur, D., Vicini, F., Wazer, D., Khan, A. (eds) Short Course Breast Radiotherapy. Springer, Cham. https://doi.org/10.1007/978-3-319-24388-7_8

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