Abstract
Drug-induced pemphigoid and drug-induced linear IgA disease can be difficult to differentiate from bullous pemphigoid (BP), mucous membrane pemphigoid (MMP), and linear IgA disease (LAD) because of only minor differences in clinical, histopathologic, and immunopathologic features. However, differentiation can be of major importance because of a different approach, treatment, and outcome. Diagnosis is mainly based on the time relation between start of the suspected drug(s) and onset of the lesions. Drug-induced BP and drug-induced LAD tend to be self-limiting after withdrawal of the culprit drug.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Lo Schiavo A, Ruocco E, Brancaccio G, Caccavale S, Ruocco V, Wolf R. Bullous pemphigoid: etiology, pathogenesis, and inducing factors: facts and controversies. Clin Dermatol. 2013;31(4):391–9.
Stavropoulos PG, Soura E, Antoniou C. Drug-induced pemphigoid: a review of the literature. J Eur Acad Dermatol Venereol. 2014;28(9):1133–40.
Bastuji-Garin S, Joly P, Picard-Dahan C, Bernard P, Vaillant L, Pauwels C, Salagnac V, Lok C, Roujeau JC. Drugs associated with bullous pemphigoid. A case-control study. Arch Dermatol. 1996;132(3):272–6.
Vassileva S. Drug-induced pemphigoid: bullous and cicatricial. Clin Dermatol. 1998;16(3):379–87.
Chanal J, Ingen-Housz-Oro S, Ortonne N, Duong TA, Thomas M, Valeyrie-Allanore L, Lebrun-Vignes B, André C, Roujeau JC, Chosidow O, Wolkenstein P. Linear IgA bullous dermatosis: comparison between the drug-induced and spontaneous forms. Br J Dermatol. 2013;169(5):1041–8.
Fortuna G, Salas-Alanis JC, Guidetti E, Marinkovich MP. A critical reappraisal of the current data on drug-induced linear immunoglobulin A bullous dermatosis: a real and separate nosological entity? J Am Acad Dermatol. 2012;66(6):988–94.
Camilleri M, Pace JL. Drug-induced linear immunoglobulin-A bullous dermatosis. Clin Dermatol. 1998;16(3):389–91.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Kardaun, S.H., Meijer, J.M. (2016). Drug-Induced Pemphigoid and Linear IgA Disease. In: Jonkman, M. (eds) Autoimmune Bullous Diseases. Springer, Cham. https://doi.org/10.1007/978-3-319-23754-1_19
Download citation
DOI: https://doi.org/10.1007/978-3-319-23754-1_19
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-23753-4
Online ISBN: 978-3-319-23754-1
eBook Packages: MedicineMedicine (R0)