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Narcolepsy pp 129–146Cite as

Hypersomnias Other Than Narcolepsy: Differential Diagnosis

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Abstract

Hypersomnias other than narcolepsy represent the largest number of hypersomnias. According to the International Classification of Sleep Disorders, Third Edition, they include sleep-related breathing disorders, mainly the obstructive sleep apnea syndrome (OSAS), and central disorders of hypersomnolence, e.g., idiopathic hypersomnia, Kleine–Levin syndrome (KLS), hypersomnia due to a medical disorder, hypersomnia due to medication or substance, hypersomnia associated with a psychiatric disorder, and insufficient sleep syndrome.

In this chapter, we will start by giving some necessary definitions, then consider the sequence of clinical and laboratory investigations leading to the differential diagnosis of hypersomnia, and finally review the individual hypersomnias with the emphasis put on clinical features, laboratory findings, and pathophysiology in regard to the continuous development of the latter.

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  1. Department of Neurology, Gui de Chauliac Hospital, 80, Avenue Augustin Fliche, 34295, Montpellier Cedex 5, France

    Michel Billiard MD

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  1. Montefiore Medical Center Narcolepsy Institute, Bronx, New York, USA

    Meeta Goswami

  2. Montefiore Hospital Sleep-Wake Disorders Center, Bronx, New York, USA

    Michael J. Thorpy

  3. Somnogen Canada Inc, President and Chief Executive Officer, Toronto, Ontario, Canada

    S.R. Pandi-Perumal

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Billiard, M. (2016). Hypersomnias Other Than Narcolepsy: Differential Diagnosis. In: Goswami, M., Thorpy, M., Pandi-Perumal, S. (eds) Narcolepsy. Springer, Cham. https://doi.org/10.1007/978-3-319-23739-8_10

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