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Multimodal Imaging in Uveitis pp 25–36Cite as

Indocyanine Green Angiography in Uveitis

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Abstract

The visualization of the choroidal vasculature with the use of indocyanine green angiography (ICGA) has led to an improved understanding of choroid involving uveitic entities and their pathogenesis. ICGA has also emerged as having an important role in the diagnosis and follow-up of uveitic diseases, as well as in evaluating the full extent of choriocapillaris and choroidal stromal involvement in these diseases. This chapter reviews ICGA findings in the different chorioretinal uveitic diseases.

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References

  1. Stanga PE, Lim JI, Hamilton P. Indocyanine green angiography in chorioretinal diseases: indications and interpretation: an evidence-based update. Ophthalmology. 2003;110(1):15–21. quiz 22

    Article  PubMed  Google Scholar 

  2. Desmettre T, Devoisselle JM, Mordon S. Fluorescence properties and metabolic features of indocyanine green (ICG) as related to angiography. Surv Ophthalmol. 2000;45(1):15–27.

    Article  CAS  PubMed  Google Scholar 

  3. Herbort CP, Mantovani A, Papadia M. Use of indocyanine green angiography in uveitis. Int Ophthalmol Clin. 2012;52(4):13–31.

    Article  PubMed  Google Scholar 

  4. Cao JH, Silpa-Archa S, Freitas-Neto CA, Foster CS. Birdshot chorioretinitis lesions on indocyanine green angiography as an indicator of disease activity. Retina. 2016;36(9):1751–7.

    Article  PubMed  Google Scholar 

  5. Yannuzzi LA. Indocyanine green angiography: a perspective on use in the clinical setting. Am J Ophthalmol. 2011;151(5):745–751.e1.

    Article  PubMed  Google Scholar 

  6. Silpa-Archa S, Silpa-Archa N, Preble JM, Foster CS. Vogt-Koyanagi-Harada syndrome: perspectives for immunogenetics, multimodal imaging, and therapeutic options. Autoimmun Rev. 2016;15(8):809–19.

    Article  CAS  PubMed  Google Scholar 

  7. Abouammoh MA, Gupta V, Hemachandran S, Herbort CP, Abu El-Asrar AM. Indocyanine green angiographic findings in initial-onset acute Vogt-Koyanagi-Harada disease. Acta Ophthalmol. 2016;94(6):573–8.

    Article  PubMed  Google Scholar 

  8. Knecht PB, Mantovani A, Herbort CP. Indocyanine green angiography-guided management of Vogt-Koyanagi-Harada disease: differentiation between choroidal scars and active lesions. Int Ophthalmol. 2013;33(5):571–7.

    Article  PubMed  Google Scholar 

  9. Takemoto Y, Namba K, Mizuuchi K, et al. Choroidal circulation impairment during the anterior recurrence of Vogt-Koyanagi-Harada disease confirmed with indocyanine green angiography and laser speckle flowgraphy. Acta Ophthalmol. 2016;94(7):e629–36.

    Article  PubMed  Google Scholar 

  10. Chang GC, Young LH. Sympathetic ophthalmia. Semin Ophthalmol. 2011;26(4-5):316–20.

    Article  PubMed  Google Scholar 

  11. Mahajan S, Invernizzi A, Agrawal R, Biswas J, Rao NA, Gupta V. Multimodal imaging in sympathetic ophthalmia. Ocul Immunol Inflamm. 2017;25:152–9.

    Article  PubMed  Google Scholar 

  12. Modi YS, Epstein A, Bhaleeya S, Harbour JW, Albini T. Multimodal imaging of sarcoid choroidal granulomas. J Ophthalmic Inflamm Infect. 2013;3(1):58.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Levinson RD, Brezin A, Rothova A, Accorinti M, Holland GN. Research criteria for the diagnosis of birdshot chorioretinopathy: results of an international consensus conference. Am J Ophthalmol. 2006;141(1):185–7.

    Article  PubMed  Google Scholar 

  14. Reddy AK, Gonzalez MA, Henry CR, Yeh S, Sobrin L, Albini TA. Diagnostic sensitivity of indocyanine green angiography for birdshot chorioretinopathy. JAMA Ophthalmol. 2015;133(7):840–3.

    Article  PubMed  Google Scholar 

  15. Gass JD. Acute posterior multifocal placoid pigment epitheliopathy. Arch Ophthalmol. 1968;80(2):177–85.

    Article  CAS  PubMed  Google Scholar 

  16. Deutman AF, Oosterhuis JA, Boen-Tan TN, Aan de Kerk AL. Acute posterior multifocal placoid pigment epitheliopathy. Pigment epitheliopathy of choriocapillaritis. Br J Ophthalmol. 1972;56(12):863–74.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Schneider U, Inhoffen W, Gelisken F. Indocyanine green angiography in a case of unilateral recurrent posterior acute multifocal placoid pigment epitheliopathy. Acta Ophthalmol Scand. 2003;81(1):72–5.

    Article  PubMed  Google Scholar 

  18. Mrejen S, Sarraf D, Chexal S, Wald K, Freund KB. Choroidal involvement in acute posterior multifocal placoid pigment epitheliopathy. Ophthalmic Surg Lasers Imaging Retina. 2016;47(1):20–6.

    Article  PubMed  Google Scholar 

  19. Jampol LM, Sieving PA, Pugh D, Fishman GA, Gilbert H. Multiple evanescent white dot syndrome. I Clinical findings. Arch Ophthalmol. 1984;102(5):671–4.

    Article  CAS  PubMed  Google Scholar 

  20. Marsiglia M, Gallego-Pinazo R, Cunha de Souza E, et al. Expanded clinical spectrum of multiple evanescent white dot syndrome with multimodal imaging. Retina. 2016;36(1):64–74.

    Article  PubMed  Google Scholar 

  21. Gross NE, Yannuzzi LA, Freund KB, Spaide RF, Amato GP, Sigal R. Multiple evanescent white dot syndrome. Arch Ophthalmol. 2006;124(4):493–500.

    Article  PubMed  Google Scholar 

  22. Pichi F, Srvivastava SK, Chexal S, et al. En face optical coherence tomography and optical coherence tomography angiography of multiple evanescent white dot syndrome: new insights into pathogenesis. Retina. 2016;36(Suppl 1):S178–88.

    Article  PubMed  Google Scholar 

  23. Gaudric A, Mrejen S. Why the dots are black only in the late phase of the indocyanine green angiography in multiple evanescent white dot syndrome. Retin Cases Brief Rep. 2017;11(Suppl 1):S81–5.

    Article  PubMed  Google Scholar 

  24. Thorne JE, Wittenberg S, Jabs DA, et al. Multifocal choroiditis with panuveitis incidence of ocular complications and of loss of visual acuity. Ophthalmology. 2006;113(12):2310–6.

    Article  PubMed  Google Scholar 

  25. Ahnood D, Madhusudhan S, Tsaloumas MD, Waheed NK, Keane PA, Denniston AK. Punctate inner choroidopathy: a review. Surv Ophthalmol. 2017;62(2):113–126. doi: https://doi.org/10.1016/j.survophthal.2016.10.003. Epub 2016 Oct 15. Review. PubMed PMID: 27751823.

  26. Spaide RF, Goldberg N, Freund KB. Redefining multifocal choroiditis and panuveitis and punctate inner choroidopathy through multimodal imaging. Retina. 2013;33(7):1315–24.

    Article  PubMed  Google Scholar 

  27. Vadalà M, Lodato G, Cillino S. Multifocal choroiditis: indocyanine green angiographic features. Ophthalmologica. 2001;215(1):16–21.

    Article  PubMed  Google Scholar 

  28. Nazari Khanamiri H, Rao NA. Serpiginous choroiditis and infectious multifocal serpiginoid choroiditis. Surv Ophthalmol. 2013;58(3):203–32.

    Article  PubMed  Google Scholar 

  29. Giovannini A, Mariotti C, Ripa E, Scassellati-Sforzolini B. Indocyanine green angiographic findings in serpiginous choroidopathy. Br J Ophthalmol. 1996;80(6):536–40.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. El Ameen A, Herbort CP Jr. Serpiginous choroiditis imaged by optical coherence tomography angiography. Retin Cases Brief Rep. 2016. doi: https://doi.org/10.1097/ICB.0000000000000512. [Epub ahead of print]. PubMed PMID: 28033230.

  31. Carreño E, Fernandez-Sanz G, Sim DA, et al. Multimodal imaging of macular serpiginous choroidopathy from acute presentation to quiescence. Ophthalmic Surg Lasers Imaging Retina. 2015;46(2):266–70.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. National Eye Institute, National Institutes of Health, Bethesda, Maryland, 20892, USA

    Shilpa Kodati MD

  2. Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, 33136, USA

    Samuel P. Burke BA & Thomas A. Albini MD

Authors
  1. Shilpa Kodati MD
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  2. Samuel P. Burke BA
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  3. Thomas A. Albini MD
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Corresponding author

Correspondence to Thomas A. Albini MD .

Editor information

Editors and Affiliations

  1. National Eye Institute National Institutes of Health, Bethesda, Maryland, USA

    H. Nida Sen

  2. Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama, USA

    Russell W. Read

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Kodati, S., Burke, S.P., Albini, T.A. (2018). Indocyanine Green Angiography in Uveitis. In: Sen, H., Read, R. (eds) Multimodal Imaging in Uveitis. Springer, Cham. https://doi.org/10.1007/978-3-319-23690-2_2

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  • DOI: https://doi.org/10.1007/978-3-319-23690-2_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-23689-6

  • Online ISBN: 978-3-319-23690-2

  • eBook Packages: MedicineMedicine (R0)

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